Beyond simple TCR depletion model: How MHC class and sex affect trade-offs constraining MHC gene number evolution?
2019/32/C/NZ8/00440
Keywords
Descriptors
- NZ8_001: Biologia ewolucyjna
- NZ6_003: Immunologia zwierząt
Panel
NZ8 – Evolutionary and environmental biology: evolution, ecology, population biology, biodiversity, biogeography
Host institution
Uniwersytet Jagielloński, Wydział Biologii
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 2
Call
SONATINA 3 – announced on 2018-12-14
- Amount awarded
- 899 416 PLN
- Project start date
- 2019-11-29
- Project end date
- 2024-05-28
- Project duration
- 54 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (4)
-
Cross-reactivity of T cell-specific antibodies in the bank vole (Myodes glareolus)
- Authors:
- Magdalena Migalska, Kazimierz Węglarczyk, Renata Mężyk-Kopeć, Katarzyna Baliga-Klimczyk, Joanna Homa
- Academic press:
- Journal of Immunological Methods (year: 2023, volume: 520, pages: 113524), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.jim.2023.113524 – link to the publication
-
Long term patterns of association between MHC and helminth burdens in the bank vole support Red Queen dynamics
- Authors:
- Magdalena Migalska, Karolina Przesmycka, Mohammed Alsarraf, Anna Bajer, Jolanta Behnke-Borowczyk, Maciej Grzybek, Jerzy M. Behnke, Jacek Radwan
- Academic press:
- Molecular Ecology (year: 2022, volume: 31 (12), pages: 3400-3415), Publisher: Wiley-Blackwell
- Status:
- Published
- DOI:
- 10.1111/mec.16486 – link to the publication
-
Coevolution between MHC class I and Antigen Processing Genes in salamanders
- Authors:
- Gemma Palomar, Katarzyna Dudek, Magdalena Migalska, J W Arntzen, G Francesco Ficetola, Dušan Jelić, Elizabeth Jockusch, Inigo Martínez-Solano, Masatoshi Matsunami, H Bradley Shaffer, Judit Vörös, Bruce Waldman, Ben Wielstra, Wiesław Babik
- Academic press:
- Molecular Biology and Evolution (year: 2021, volume: 38, pages: 5092–5106), Publisher: Oxford University Press
- Status:
- Published
- DOI:
- 10.1093/molbev/msab237 – link to the publication
-
Evolutionary trade-offs constraining the MHC gene expansion: beyond simple TCR depletion model
- Authors:
- Magdalena Migalska, Kazimierz Węglarczyk, katarzyna Dudek, Joanna Homa
- Academic press:
- Frontiers in Immunology (year: 2024, volume: 14 - 2023, pages: 1240723), Publisher: Frontiers
- Status:
- Published
- DOI:
- 10.3389/fimmu.2023.1240723 – link to the publication