Zastosowanie metod uczenia maszynowego i symulacji molekularnych w badaniu zależności pomiędzy sekwencją, strukturą a funkcją białek

2019/32/T/NZ1/00323

Descriptors

  • NZ2_007: Bioinformatyka
  • NZ2_008: Biologia obliczeniowa
  • NZ1_004: Biologia strukturalna

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Instytut Biologii Doświadczalnej im. M. Nenckiego PAN

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Jan Marcin Ludwiczak

Number of co-investigators in the project: 2

Call

ETIUDA 7 – announced on 2018-12-14

Amount awarded
125 840 PLN
Project start date
2019-10-01
Project end date
2020-09-30
Project duration
12 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (5)

  1. β-sheet breakers with consecutive phenylalanines: Insights into mechanism of dissolution of β-amyloid fibrils

    Authors:
    A. Jarmuła, J. Ludwiczak, D. Stępkowski
    Academic press:
    Proteins: Structure, Function, and Bioinformatics (year: 2021, volume: 89, pages: 762-780), Publisher: Wiley Periodicals LLC
    Status:
    Published
    DOI:
    10.1002/prot.26057 – link to the publication
  2. Revealing biophysical properties of KfrA-type proteins as a novel class of cytoskeletal, coiled-coil plasmid-encoded proteins

    Authors:
    M. Adamczyk, E. Lewicka, R. Szatkowska, H. Nieznanska, J. Ludwiczak, M. Jasiński, S. Dunin-Horkawicz, E. Sitkiewicz, B. Swiderska, G. Goch, G. Jagura-Burdzy
    Academic press:
    BMC Microbiology (year: 2021, volume: 21, pages: 32), Publisher: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s12866-020-02079-w – link to the publication
  3. Self-analysis of repeat proteins reveals evolutionarily conserved patterns

    Authors:
    M. Merski, K. Młynarczyk, J. Ludwiczak, J. Skrzeczkowski, S. Dunin-Horkawicz, MW. Górna
    Academic press:
    BMC Bioinformatics (year: 2020, volume: 21, pages: 179-196), Publisher: BioMed Central
    Status:
    Published
    DOI:
    10.1186/s12859-020-3493-y – link to the publication
  4. C8J_1298, a bifunctional thiol oxidoreductase of Campylobacter jejuni, affects Dsb (disulfide bond) network functioning

    Authors:
    A. Banaś, K. Bocian-Ostrzycka, M. Plichta, S. Dunin-Horkawicz, J. Ludwiczak, J. Płaczkiewicz, E. Jagusztyn-Krynicka
    Academic press:
    PLOS One (year: 2020, volume: 15, pages: e0230366), Publisher: Public Library of Science
    Status:
    Published
    DOI:
    10.1371/journal.pone.0230366 – link to the publication
  5. A library of coiled-coil domains: from regular bundles to peculiar twists

    Authors:
    K. Szczepaniak, A. Bukala, A.M. da Silva Neto, J. Ludwiczak, S. Dunin-Horkawicz
    Academic press:
    Bioinformatics (year: 2020, volume: 36, pages: 5368-5376), Publisher: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/bioinformatics/btaa1041 – link to the publication

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Graphic design and implementation: Jakub Piotrowski