The effect of phloroglucinol on the development of insulin resistance in non-alc

The effect of phloroglucinol on the development of insulin resistance in non-alcoholic fatty liver disease (NAFLD).

2018/31/N/NZ7/03242

Keywords

Descriptors

NZ7_14: Farmacja, farmakoterapia, farmakologia
NZ4_11: Metabolizm
NZ4_6: Endokrynologia

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim

Voivodeship: podlaskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Krzysztof Drygalski

Number of co-investigators in the project: 3

Call

PRELUDIUM 16 – announced on 2018-09-14

Amount awarded: 210 000 PLN
Project start date: 2019-07-08
Project end date: 2022-07-07
Project duration: 36 months (the same as in the proposal)
Project status: Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

Sonifikator - homogenizator ultradźwiękowy.

Information in the final report

Publication in academic press/journals (2)

Phloroglucinol prevents albumin glycation as well as diminishes ROS production, glycooxidative damage, nitrosative stress and inflammation in hepatocytes treated with high glucose

Authors:
Krzysztof Drygalski, Eliza Fereniec, Anna Zalewska, Adam Krętowski, Małgorzata Żendzian-Piotrowska, Mateusz Maciejczyk

Academic press:
Biomedicine & Pharmacotherapy (year: 2021, volume: 142, pages: 111958), Publisher: Elsevier

Status:
Published

DOI:
10.1016/j.biopha.2021.111958 – link to the publication
Phloroglucinol Strengthens the Antioxidant Barrier and Reduces Oxidative/Nitrosative Stress in Nonalcoholic Fatty Liver Disease (NAFLD)

Authors:
Krzysztof Drygalski, Katarzyna Siewko, Andrzej Chomentowski, Cezary Odrzygóźdź, Anna Zalewska, Adam Krętowski, Mateusz Maciejczyk

Academic press:
Oxidative Medicine and Cellular Longevity (year: 2021, volume: 2021, pages: 18), Publisher: Hindawi

Status:
Published

DOI:
10.1155/2021/8872702 – link to the publication

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