Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Polyphenols from raspberries and their metabolites as factors regulating mechanisms of nonalcoholic fatty liver disease

2018/31/D/NZ9/02196

Keywords:

polyphenolic compounds microbiota activity lipid and glucose metabolism bile acids mechanisms of liver metabolic disorders rats

Descriptors:

  • NZ9_7: Nutrition and food sciences

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk

woj. warmińsko-mazurskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Bartosz Fotschki 

Number of co-investigators in the project: 4

Call: SONATA 14 - announced on 2018-09-14

Amount awarded: 1 295 260 PLN

Project start date (Y-m-d): 2019-06-18

Project end date (Y-m-d): 2023-06-17

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Termostat blokowy.
  2. Systemy gradientowy HPLC z autosamplerem sprzężony z detektorem SPD-M20A DAD (300 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Prebiotics together with raspberry polyphenolic extract mitigate the development of nonalcoholic fatty liver diseases in Zucker rats
    Authors:
    Bartosz Fotschki, Michał Sójka, Monika Kosmala, Jerzy Juśkiewicz
    Academic press:
    Nutrients (rok: 2023, tom: 15(2), strony: 3115 (1-15)), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nu15143115 - link to the publication
  2. Dose-Related Regulatory Effect of Raspberry Polyphenolic Extract on Cecal Microbiota Activity, Lipid Metabolism and Inflammation in Rats Fed a Diet Rich in Saturated Fats
    Authors:
    Bartosz Fotschki, Ewelina Cholewińska, Katarzyna Ognik, Michał Sójka, Joanna Milala, Joanna Fotschki, Wiesław Wiczkowski, Jerzy Juśkiewicz
    Academic press:
    Nutrients (rok: 2023, tom: 15(2), strony: 354 (1-15)), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nu15020354 - link to the publication
  3. Fructo-oligosaccharides and pectins enhance beneficial effects of raspberry polyphenols in rats with nonalcoholic fatty liver
    Authors:
    Bartosz Fotschki, Jerzy Juśkiewicz Adam Jurgoński, Michał Sójka
    Academic press:
    Nutrients (rok: 2021, tom: 13, strony: 833), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nu13030833 - link to the publication
  4. Stimulation of the intestinal microbiota with prebiotics enhances hepatic levels of dietary polyphenolic compounds, lipid metabolism and antioxidant status in healthy rats
    Authors:
    Bartosz Fotschki, Wiesław Wiczkowski, Tomasz Sawicki, Michał Sójka, Kamil Myszczyński, Katarzyna Ognik, Jerzy Juśkiewicz1
    Academic press:
    Food Research International (rok: 2022, tom: 160, strony: 111754), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.foodres.2022.111754 - link to the publication

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