Antimicrobial and antibiofilm properties of novel arylosulfonamide derivates towards multidrug-resistant and biofilm-forming Staphylococcus epidermidis strains

2018/31/N/NZ6/03339

Keywords

Descriptors

  • NZ6_4: Bakteriologia

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Uniwersytet Jagielloński- Collegium Medicum, Collegium Medicum; Wydział Farmaceutyczny

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Iwona Danuta Skiba-Kurek

Number of co-investigators in the project: 3

Call

PRELUDIUM 16 – announced on 2018-09-14

Amount awarded
209 200 PLN
Project start date
2019-07-11
Project end date
2022-07-10
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Laptop. Cost: 5 000 PLN
  2. Loża z laminarnym nawiewem jałowego powietrza II klasy bezpieczeństwa. Cost: 25 000 PLN

Information in the final report

Publication in academic press/journals (4)

  1. Synergistic ROS-Associated Antimicrobial Activity of Silver Nanoparticles and Gentamicin Against Staphylococcus epidermidis

    Authors:
    Paulina Mazur, Iwona Skiba-Kurek, Paulina Mrowiec, Elżbieta Karczewska, Ryszard Drożdż
    Academic press:
    International Journal of Nanomedicine (year: 2020, volume: 15, pages: 3551-3562), Publisher: Dove Press
    Status:
    Published
    DOI:
    10.2147/IJN.S246484 – link to the publication
  2. Evaluation of Biofilm Formation and Prevalence of Multidrug-Resistant Strains of Staphylococcus epidermidis Isolated from Neonates with Sepsis in Southern Poland

    Authors:
    Iwona Skiba-Kurek, Paweł Nowak, Joanna Empel, Magdalena Tomczak, Joanna Klepacka, Iwona Sowa-Sierant, Iwona Żak, Bartosz Pomierny, Elżbieta Karczewska
    Academic press:
    Pathogens (year: 2021, volume: 10, pages: 46038), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/pathogens10070877 – link to the publication
  3. Design, synthesis and activity against Staphylococcus epidermidis of 5‐chloro‐2‐ or 5‐chloro‐4‐methyl‐9H‐xanthen‐9‐one and some of its derivatives

    Authors:
    Gabriela Mazur, Iwona Skiba-Kurek, Elżbieta Karczewska, Katarzyna Pańczyk-Straszak, Joanna Jaworska, Anna M. Waszkielewicz
    Academic press:
    Chemical Biology & Drug Design (year: 2021, volume: 97, pages: 674-685), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1111/cbdd.13803 – link to the publication
  4. Improving Activity of New Arylurea Agents against Multidrug-Resistant and Biofilm-Producing Staphylococcus epidermidis

    Authors:
    Vittorio Canale, Iwona Skiba-Kurek, Karolina Klesiewicz, Monika Papież, Marlena Ropek, Bartosz Pomierny, Kamil Piska, Paulina Koczurkiewicz-Adamczyk, Joanna Empel, Elżbieta Karczewska, Paweł Zajdel
    Status:
    Accepted for publication

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Graphic design and implementation: Jakub Piotrowski