Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Antimicrobial and antibiofilm properties of novel arylosulfonamide derivates towards multidrug-resistant and biofilm-forming Staphylococcus epidermidis strains

2018/31/N/NZ6/03339

Keywords:

Staphylococcus epidermidis antibiotic resistance biofilm MIC antibacterial activity of compounds

Descriptors:

  • NZ6_4: Bacteriology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński - Collegium Medicum, Collegium Medicum, Wydział Farmaceutyczny

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Iwona Skiba-Kurek 

Number of co-investigators in the project: 3

Call: PRELUDIUM 16 - announced on 2018-09-14

Amount awarded: 209 200 PLN

Project start date (Y-m-d): 2019-07-11

Project end date (Y-m-d): 2022-07-10

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Laptop (5 000 PLN)
  2. Loża z laminarnym nawiewem jałowego powietrza II klasy bezpieczeństwa (25 000 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  1. Design, synthesis and activity against Staphylococcus epidermidis of 5‐chloro‐2‐ or 5‐chloro‐4‐methyl‐9H‐xanthen‐9‐one and some of its derivatives
    Authors:
    Gabriela Mazur, Iwona Skiba-Kurek, Elżbieta Karczewska, Katarzyna Pańczyk-Straszak, Joanna Jaworska, Anna M. Waszkielewicz
    Academic press:
    Chemical Biology & Drug Design (rok: 2021, tom: 97, strony: 674-685), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/cbdd.13803 - link to the publication
  2. Evaluation of Biofilm Formation and Prevalence of Multidrug-Resistant Strains of Staphylococcus epidermidis Isolated from Neonates with Sepsis in Southern Poland
    Authors:
    Iwona Skiba-Kurek, Paweł Nowak, Joanna Empel, Magdalena Tomczak, Joanna Klepacka, Iwona Sowa-Sierant, Iwona Żak, Bartosz Pomierny, Elżbieta Karczewska
    Academic press:
    Pathogens (rok: 2021, tom: 10, strony: 45307), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pathogens10070877 - link to the publication
  3. Improving Activity of New Arylurea Agents against Multidrug-Resistant and Biofilm-Producing Staphylococcus epidermidis
    Authors:
    Vittorio Canale, Iwona Skiba-Kurek, Karolina Klesiewicz, Monika Papież, Marlena Ropek, Bartosz Pomierny, Kamil Piska, Paulina Koczurkiewicz-Adamczyk, Joanna Empel, Elżbieta Karczewska, Paweł Zajdel
    Academic press:
    ACS Medicinal Chemistry Letters (rok: 2024, tom: bd, strony: bd), Wydawca: American Chemical Society
    Status:
    Accepted for publication
    DOI:
    10.1021/acsmedchemlett.3c00536 - link to the publication
  4. Synergistic ROS-Associated Antimicrobial Activity of Silver Nanoparticles and Gentamicin Against Staphylococcus epidermidis
    Authors:
    Paulina Mazur, Iwona Skiba-Kurek, Paulina Mrowiec, Elżbieta Karczewska, Ryszard Drożdż
    Academic press:
    International Journal of Nanomedicine (rok: 2020, tom: 15, strony: 3551-3562), Wydawca: Dove Press
    Status:
    Published
    DOI:
    10.2147/IJN.S246484 - link to the publication

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