Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Studies on the immunomodulatory effects of bactriophjages on functions of immune cells

2018/31/B/NZ6/03999

Keywords:

bacteriophages immune cells function gene expression cytokine production

Descriptors:

  • NZ6_5: Virology
  • NZ6_1: Adaptive and innate immunity
  • NZ6_2: Clinical immunology

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Ryszard Międzybrodzki 

Number of co-investigators in the project: 9

Call: OPUS 16 - announced on 2018-09-14

Amount awarded: 1 499 000 PLN

Project start date (Y-m-d): 2019-09-11

Project end date (Y-m-d): 2024-09-10

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Therapeutic Perspectives and Mechanistic Insights of Phage Therapy in Allotransplantation
    Authors:
    Kenneth J Dery, Andrzej Górski, Ryszard Międzybrodzki, Douglas G Farmer, Jerzy W Kupiec-Weglinski
    Academic press:
    Transplantation , Wydawca: Wolters Kluwer
    Status:
    Accepted for publication
    DOI:
    10.1097/TP.0000000000003565 - link to the publication
  2. Pharmacokinetic and pharmacodynamic obstacles for phage therapy from the perspective of clinical practice
    Authors:
    Ryszard Międzybrodzki, Hubert Kasprzak, Sławomir Letkiewicz, Paweł Rogóż, Maciej Żaczek, Jamon Thomas, Andrzej Górski
    Academic press:
    Clinical Infectious Diseases (rok: 2023, tom: 77 (Supplement 5), strony: S395-S400), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/cid/ciad516 - link to the publication
  3. The effects of T4 and A5/80 phages on the expression of immunologically important genes in differentiated Caco-2 cells
    Authors:
    Borysowski J, Międzybrodzki R, Przybylski M, Owczarek B, Weber-Dąbrowska B, Górski A.
    Academic press:
    Postępy Med. Hig. Dośw. (rok: 2020, tom: 74, strony: 371-376), Wydawca: Index Copernicus International
    Status:
    Published
    DOI:
    10.5604/01.3001.0014.3919 - link to the publication
  4. Therapeutic phages as modulators of the immune response: practical implications
    Authors:
    Andrzej Górski, Ryszard Międzybrodzki, Ewa Jończyk-Matysiak, Monika Kniotek, and Sławomir Letkiewicz
    Academic press:
    Clinical Infectious Diseases (rok: 2023, tom: 77 (Supplement 5), strony: S433-S439), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/cid/ciad483 - link to the publication

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