The mechanisms of recognition and matchmaking of small noncoding RNAs and regulated mRNAs by the ProQ protein in Escherichia coli.

2018/31/B/NZ1/02612

Keywords

Descriptors

  • NZ1_2: Biochemia
  • NZ1_1: Biologia molekularna

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Mikołaj Olejniczak

Number of co-investigators in the project: 4

Call

OPUS 16 – announced on 2018-09-14

Amount awarded
1 095 040 PLN
Project start date
2019-07-09
Project end date
2024-03-08
Project duration
56 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (4)

  1. Biochemical and genetic dissection of the RNA-binding surface of the FinO domain of Escherichia coli ProQ

    Authors:
    Ewa M. Stein, Suxuan Wang, Katherine G. Dailey, Chandra M. Gravel, Shiying Wang, Mikołaj Olejniczak, Katherine E. Berry
    Academic press:
    RNA (year: 2023, volume: 29, pages: 1772-1791), Publisher: COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
    Status:
    Published
    DOI:
    10.1261/rna.079697.123 – link to the publication
  2. Determinants of RNA recognition by the FinO domain of the Escherichia coli ProQ protein

    Authors:
    Ewa M. Stein, Joanna Kwiatkowska, Maciej M. Basczok, Chandra M. Gravel, Katherine E. Berry, Mikołaj Olejniczak
    Academic press:
    Nucleic Acids Research (year: 2020, volume: 48, pages: 7502-7519), Publisher: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gkaa497 – link to the publication
  3. KH domain proteins: Another family of bacterial RNA matchmakers?

    Authors:
    Mikolaj Olejniczak, Xiaofang Jiang, Maciej M. Basczok, Gisela Storz
    Academic press:
    Molecular Microbiology (year: 2022, volume: 117, pages: 46314), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1111/mmi.14842 – link to the publication
  4. Bacteriophage-encoded 24B_1 molecule resembles herpesviral microRNAs and plays a crucial role in the development of both the virus and its host

    Authors:
    Sylwia Bloch, Natalia Lewandowska, Joanna Zwolenkiewicz, Paulina Mach, Aleksandra Łukasiak, Mikołaj Olejniczak, Logan W. Donaldson, Grzegorz Węgrzyn, Bożena Nejman-Faleńczyk
    Academic press:
    PLOS ONE (year: 2023, volume: 18, pages: e0296038), Publisher: PUBLIC LIBRARY SCIENCE
    Status:
    Published
    DOI:
    10.1371/journal.pone.0296038 – link to the publication

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