Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

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The mechanisms of recognition and matchmaking of small noncoding RNAs and regulated mRNAs by the ProQ protein in Escherichia coli.

2018/31/B/NZ1/02612

Keywords:

ProQ Hfq noncoding RNA in bacteria RNA-protein interactions RNA chaperone proteins

Descriptors:

  • NZ1_2:
  • NZ1_1:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Mikołaj Olejniczak 

Number of co-investigators in the project: 4

Call: OPUS 16 - announced on 2018-09-14

Amount awarded: 1 095 040 PLN

Project start date (Y-m-d): 2019-07-09

Project end date (Y-m-d): 2024-03-08

Project duration:: 56 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Biochemical and genetic dissection of the RNA-binding surface of the FinO domain of Escherichia coli ProQ
    Authors:
    Ewa M. Stein, Suxuan Wang, Katherine G. Dailey, Chandra M. Gravel, Shiying Wang, Mikołaj Olejniczak, Katherine E. Berry
    Academic press:
    RNA (rok: 2023, tom: 29, strony: 1772-1791), Wydawca: COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
    Status:
    Published
    DOI:
    10.1261/rna.079697.123 - link to the publication
  2. Bacteriophage-encoded 24B_1 molecule resembles herpesviral microRNAs and plays a crucial role in the development of both the virus and its host
    Authors:
    Sylwia Bloch, Natalia Lewandowska, Joanna Zwolenkiewicz, Paulina Mach, Aleksandra Łukasiak, Mikołaj Olejniczak, Logan W. Donaldson, Grzegorz Węgrzyn, Bożena Nejman-Faleńczyk
    Academic press:
    PLOS ONE (rok: 2023, tom: 18, strony: e0296038), Wydawca: PUBLIC LIBRARY SCIENCE
    Status:
    Published
    DOI:
    10.1371/journal.pone.0296038 - link to the publication
  3. KH domain proteins: Another family of bacterial RNA matchmakers?
    Authors:
    Mikolaj Olejniczak, Xiaofang Jiang, Maciej M. Basczok, Gisela Storz
    Academic press:
    Molecular Microbiology (rok: 2022, tom: 117, strony: 45949), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1111/mmi.14842 - link to the publication
  4. Determinants of RNA recognition by the FinO domain of the Escherichia coli ProQ protein
    Authors:
    Ewa M. Stein, Joanna Kwiatkowska, Maciej M. Basczok, Chandra M. Gravel, Katherine E. Berry, Mikołaj Olejniczak
    Academic press:
    Nucleic Acids Research (rok: 2020, tom: 48, strony: 7502-7519), Wydawca: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gkaa497 - link to the publication