Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The anti-inflammatory effect of vitamin K - Mechanism of action

2018/31/N/NZ7/03900

Keywords:

vitamin K anti-inflammatory effect

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology
  • NZ3_1: Cell biology
  • NZ3_2: Cell physiology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński, Jagiellońskie Centrum Rozwoju Leków (JCET)

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Kierońska-Rudek 

Number of co-investigators in the project: 2

Call: PRELUDIUM 16 - announced on 2018-09-14

Amount awarded: 210 000 PLN

Project start date (Y-m-d): 2019-07-11

Project end date (Y-m-d): 2023-07-10

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Vorteks (1 400 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (3)
  1. Rapid reversal of phylloquinone deficiency-induced endothelial dysfunction by phylloquinone administration in hyaluronan-based nanocapsules
    Authors:
    Anna Kieronska-Rudek,, Agnieszka Kij, Anna Bar, Magdalena Sternak, Justyna Bednorz3,4, Małgorzata Janik-Hazuka3, Renata B. Kostogrys, Magdalena Franczyk-Żarów, Szczepan Zapotoczny, Stefan Chlopicki
    Academic press:
    International Journal of Nanomedicine , Wydawca: Dove Press
    Status:
    Submitted
    DOI:
    brak - link to the publication
  2. Exogenous Vitamins K Exert Anti-Inflammatory Effects Dissociated from Their Role as Substrates for Synthesis of Endogenous MK-4 in Murine Macrophages Cell Line
    Authors:
    Anna Kieronska-Rudek, Agnieszka Kij, Patrycja Kaczara, Anna Tworzydlo, Marek Napiorkowski, Katarzyna Sidoryk, Stefan Chlopicki,
    Academic press:
    Cells (rok: 2021, tom: 10, strony: 1571), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells10071571 - link to the publication
  1. Senolitic activity of vitamin K in endothelial cells and vascular smooth muscle cells
    Authors:
    Anna Kieronska-Rudek , Anna Kurpinska , Agnieszka Kij , Agnieszka Panek , Monika Pietrowska , Catherine M. Shanahan , Stefan Chlopicki
    Conference:
    28th Kraków Conference on Endothelium and 10th Cardiovascular Research Days (rok: 2022, ), Wydawca: Jagiellońskie Centrum Rozwoju Leków (JCET)
    Data:
    konferencja 12-14.12.2022
    Status:
    Published
  2. Senolityczne działanie witaminy K na śródbłonek.
    Authors:
    ANNA KIEROŃSKA-RUDEK
    Conference:
    XI Konferencja Doktorantów Uniwersytetu Jagiellońskiego -Collegium Medicum (rok: 2021, ), Wydawca: Uniwersytet Jagielloński
    Data:
    konferencja 22.05.2021
    Status:
    Published
  3. Role of endogenous vitamin MK-4 in the pharmacological action of exogenous vitamins K
    Authors:
    Anna Kierońska-Rudek, Agnieszka Kij, Stefan Chłopicki
    Conference:
    The 6th International Vitamins Conference (rok: 2021, ), Wydawca: DTU - National Food Institute
    Data:
    konferencja 22-24.09.2021
    Status:
    Published

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