The role of the MOTS-c mitochondrial peptide in the functioning of the pancreas and adipose tissue

2018/31/D/NZ4/01121

Keywords

Descriptors

  • NZ4_2: Fizjologia
  • NZ4_6: Endokrynologia
  • NZ4_11: Metabolizm

Panel

NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution

Uniwersytet Przyrodniczy w Poznaniu, Wydział Medycyny Weterynaryjnej i Nauk o Zwierzętach

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Maciej Sassek

Number of co-investigators in the project: 6

Call

SONATA 14 – announced on 2018-09-14

Amount awarded
952 820 PLN
Project start date
2019-07-24
Project end date
2025-07-23
Project duration
72 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (5)

  1. MOTS-c Impact on Muscle Cell Differentiation and Metabolism Across Fiber Types

    Authors:
    Natalia Leciejewska, Ewa Pruszyńska-Oszmałek, Paweł Kołodziejski, Dawid Szczepankiewicz, Leszek Nogowski, Maciej Sassek
    Academic press:
    Cellular Physiology and Biochemistry (year: 2025, volume: 21;59(1), pages: 34-46), Publisher: Springer
    Status:
    Published
    DOI:
    10.33594/000000755 – link to the publication
  2. MOTS-c modulates pancreatic islet function in rats and pigs in vitro

    Authors:
    Jakub Bień, Ewa Pruszynska-Oszmalek, Paweł Kolodziejski, Natalia Leciejewska, Dawid Szczepankiewicz, Emilia Grzęda, Maciej Sassek
    Academic press:
    Histohemistry and cell biology (year: 2025, volume: 6;163(1):64, pages: 163-164), Publisher: Springer
    Status:
    Published
    DOI:
    10.1007/s00418-025-02391-4 – link to the publication
  3. The Role of Peptide Hormones Discovered in the 21st Century in the Regulation of Adipose Tissue Functions

    Authors:
    Paweł A Kołodziejski, Ewa Pruszyńska-Oszmałek, Tatiana Wojciechowicz, Maciej Sassek, Natalia Leciejewska, Mariami Jasaszwili, Maria Billert, Emilian Małek, Dawid Szczepankiewicz, Magdalena Misiewicz-Mielnik, Iwona Hertig, Leszek Nogowski, Krzysztof W Nowak, Mathias Z Strowski, Marek Skrzypski
    Academic press:
    Genes (Basel) (year: 2021, volume: 17;12(5):756, pages: 756), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/genes12050756 – link to the publication
  4. MOTS-c regulates pancreatic alpha and beta cell functions in vitro

    Authors:
    Jakub Bień, Ewa Pruszyńska-Oszmałek, Paweł Kołodziejski, Natalia Leciejewska, Dawid Szczepankiewicz, Maciej Sassek
    Academic press:
    Histohemistry and cell biology (year: 2024, volume: 161(6), pages: 449-460), Publisher: Springer
    Status:
    Published
  5. Changes in MOTS-c Level in the Blood of Pregnant Women with Metabolic Disorders

    Authors:
    Małgorzata Wojciechowska, Ewa Pruszyńska-Oszmałek, Paweł A Kołodziejski, Hanna Krauss, Natalia Leciejewska, Dawid Szczepankiewicz, Jakub Bień, Marek Skrzypski, Maciej Wilczak, Maciej Sassek
    Academic press:
    Biology (year: 2021, volume: 10, pages: 1032), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/biology10101032 – link to the publication

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