Targeting microRNA-378 in a mice model of Duchenne muscular dystrophy - a weapon against hallmark symptoms of the disease?
2018/31/N/NZ4/02500
Keywords
Descriptors
- NZ4_11: Metabolizm
Panel
NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution
Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii
Voivodeship: małopolskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 3
Call
PRELUDIUM 16 – announced on 2018-09-14
- Amount awarded
- 140 000 PLN
- Project start date
- 2019-07-11
- Project end date
- 2021-07-10
- Project duration
- 24 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (3)
-
Lack of miR-378 attenuates muscular dystrophy in mdx mice
- Authors:
- Paulina Podkalicka, Olga Mucha, Iwona Bronisz-Budzyńska, Magdalena Kozakowska, Katarzyna Pietraszek-Gremplewicz, Anna Cetnarowska, Urszula Głowniak-Kwitek, Karolina Bukowska-Strakova, Maciej Cieśla, Maria Kulecka, Jerzy Ostrowski, Michał Mikuła, Anna Potulska-Chromik, Anna Kostera-Pruszczyk, Alicja Józkowicz, Agnieszka Łoboda, Józef Dulak
- Academic press:
- JCI Insight (year: 2020, volume: 5, pages: e135576), Publisher: American Society for Clinical Investigation
- Status:
- Published
- DOI:
- 10.1172/jci.insight.135576 – link to the publication
-
miR‑378 afects metabolic disturbances in the mdx model of Duchenne muscular dystrophy
- Authors:
- Paulina Podkalicka, Olga Mucha, Katarzyna Kaziród, Krzysztof Szade, Jacek Stępniewski, Liudmyla Ivanishchuk, Hirofumi Hirao, Ewelina Pośpiech, Alicja Józkowicz, Jerzy W. Kupiec‑Weglinski, Józef Dulak, Agnieszka Łoboda
- Academic press:
- Scientific Reports (year: 2022, volume: 12, pages: 3945), Publisher: Nature Publishing Group
- Status:
- Published
- DOI:
- 10.1038/s41598-022-07868-z – link to the publication
-
Molekularne mechanizmy dystrofii mięśniowej Duchenne'a i nowe możliwości terapeutyczne
- Authors:
- Paulina Podkalicka, Małgorzata Myszka, Józef Dulak, Agnieszka Łoboda
- Academic press:
- Postępy biochemii (year: 2022, volume: 68, pages: 109-122), Publisher: Warszawa : Panstwowe Wydawnictwo Naukowe
- Status:
- Published
- DOI:
- 10.18388/pb.2021_428 – link to the publication