Projects funded by the NCN
Targeting microRNA-378 in a mice model of Duchenne muscular dystrophy - a weapon against hallmark symptoms of the disease?
2018/31/N/NZ4/02500
Keywords:
Duchenne muscular dystrophy microRNA-378 fisetin
Descriptors:
- NZ4_11: Metabolism
Panel:
NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution :
Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii
woj. małopolskie
Principal investigator (from the host institution):
Number of co-investigators in the project: 3
Call: PRELUDIUM 16 - announced on 2018-09-14
Amount awarded: 140 000 PLN
Project start date (Y-m-d): 2019-07-11
Project end date (Y-m-d): 2021-07-10
Project duration:: 24 months (the same as in the proposal)
Project status: Project settled
Project description
Download the project description in a pdf file
Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
- Publication in academic press/journals (3)
- Lack of miR-378 attenuates muscular dystrophy in mdx miceAuthors:Paulina Podkalicka, Olga Mucha, Iwona Bronisz-Budzyńska, Magdalena Kozakowska, Katarzyna Pietraszek-Gremplewicz, Anna Cetnarowska, Urszula Głowniak-Kwitek, Karolina Bukowska-Strakova, Maciej Cieśla, Maria Kulecka, Jerzy Ostrowski, Michał Mikuła, Anna Potulska-Chromik, Anna Kostera-Pruszczyk, Alicja Józkowicz, Agnieszka Łoboda, Józef DulakAcademic press:JCI Insight (rok: 2020, tom: 5, strony: e135576), Wydawca: American Society for Clinical InvestigationStatus:PublishedDOI:10.1172/jci.insight.135576 - link to the publication
- Molekularne mechanizmy dystrofii mięśniowej Duchenne'a i nowe możliwości terapeutyczneAuthors:Paulina Podkalicka, Małgorzata Myszka, Józef Dulak, Agnieszka ŁobodaAcademic press:Postępy biochemii (rok: 2022, tom: 68, strony: 109-122), Wydawca: Warszawa : Panstwowe Wydawnictwo NaukoweStatus:PublishedDOI:10.18388/pb.2021_428 - link to the publication
- miR‑378 afects metabolic disturbances in the mdx model of Duchenne muscular dystrophyAuthors:Paulina Podkalicka, Olga Mucha, Katarzyna Kaziród, Krzysztof Szade, Jacek Stępniewski, Liudmyla Ivanishchuk, Hirofumi Hirao, Ewelina Pośpiech, Alicja Józkowicz, Jerzy W. Kupiec‑Weglinski, Józef Dulak, Agnieszka ŁobodaAcademic press:Scientific Reports (rok: 2022, tom: 12, strony: 3945), Wydawca: Nature Publishing GroupStatus:PublishedDOI:10.1038/s41598-022-07868-z - link to the publication