The study of the interaction between the siloxanes (silicones) and the human skin structure as well as evaluation their effects.
2018/31/B/NZ7/02801
Keywords
Descriptors
- NZ7_14: Farmacja, farmakoterapia, farmakologia
- NZ7_15: Toksykologia
Panel
NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology
Host institution
Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny
Voivodeship: pomorskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 6
Call
OPUS 16 – announced on 2018-09-14
- Amount awarded
- 896 760 PLN
- Project start date
- 2019-07-26
- Project end date
- 2024-07-25
- Project duration
- 60 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (5)
-
Comparative study of the percutaneous permeation and bioaccumulation of the controversial cyclic siloxane using frozen-thawed and nonfrozen ex vivo human skin
- Authors:
- Krystyna Mojsiewicz-Pieńkowska, Dominika Krenczkowska, Dagmara Bazar, Bartosz Wielgomas, Krzysztof Cal, Michał Kaliszan
- Academic press:
- Toxicology in vitro (year: 2022, volume: 82, pages: 46031), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.tiv.2022.105379 – link to the publication
-
Development of Safrinium dyes for new applications: fuorescent staining of bacteria, human kidney cells, and the horny layer of the epidermis
- Authors:
- FEDOROWICZ JOANNA, BAZAR DAGMARA, Brankiewicz Wioletta, Kapica Hanna, CIURA KRZESIMIR, Zalewska-Piątek Beata, Piątek Rafał, CAL KRZYSZTOF, MOJSIEWICZ-PIEŃKOWSKA KRYSTYNA, SĄCZEWSKI JAROSŁAW
- Academic press:
- Scientifc Reports (year: 2022, volume: 12, pages: 46038), Publisher: Springer Nature
- Status:
- Published
- DOI:
- 10.1038/s41598-022-19262-w – link to the publication
-
Evidence of Skin Barrier Damage by Cyclic Siloxanes (Silicones)—Using Digital Holographic Microscopy
- Authors:
- Krystyna Mojsiewicz-Pieńkowska, Ewa Stachowska, Dominika Krenczkowska, Dagmara Bazar, Frans Meijer
- Academic press:
- International Journal of Molecular Sciences (year: 2020, volume: 21, 6375, pages: 46071), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/ijms21176375 – link to the publication
-
Investigating the free volumes as nanospaces in human stratum corneum lipid bilayers using positron annihilation lifetime spectroscopy (PALS)
- Authors:
- Mojsiewicz-Pieńkowska Krystyna, Bazar Dagmara, Filipecki Jacek, Chamerski Kordian
- Academic press:
- International Journal of Molecular Science (year: 2024, volume: vol. 25, nr 12, ID 6472, pages: 46039), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/ijms25126472 – link to the publication
-
Ex vivo human skin is not a barrier for cyclic siloxanes (cyclic silicones): evidence of diffusion, bioaccumulation, and risk of dermal absorption using a new validated GC-FID procedure
- Authors:
- Krenczkowska Dominika, Mojsiewicz-Pieńkowska Krystyna, Wielgomas Bartosz, Bazar Dagmara, Jankowski Zbigniew
- Academic press:
- Pharmaceutics (year: 2020, volume: 12, 586, pages: 46045), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/pharmaceutics12060586 – link to the publication