Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Multi-omics profiling of circulating myeloid-derived suppressor cells (cMDSCs) in epithelial ovarian cancer

2018/31/N/NZ2/02338

Keywords:

cMDSCs epithelial ovarian cancer liquid biopsy multi-omics analysis

Descriptors:

  • NZ2_2: Genomics, transcriptomics, epigenomics
  • NZ2_6: Immunogenetics
  • NZ6_2: Clinical immunology

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet Medyczny w Lublinie, Wydział Lekarski

woj. lubelskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Karolina Okła 

Number of co-investigators in the project: 3

Call: PRELUDIUM 16 - announced on 2018-09-14

Amount awarded: 209 986 PLN

Project start date (Y-m-d): 2019-09-09

Project end date (Y-m-d): 2023-09-08

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Myeloid-derived suppressor cells (MDSCs) in ovarian cancer - looking back and forward.
    Authors:
    Karolina Okła
    Academic press:
    Cells (rok: 2023, tom: vol. 12 nr 14, [art. nr] 1912, strony: s. 1-12), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells12141912 - link to the publication
  2. Accumulation of blood‑circulating PD‑L1‑expressing M‑MDSCs and monocytes/ macrophages in pretreatment ovarian cancer patients is associated with soluble PD‑L1
    Authors:
    Karolina Okła , Alicja Rajtak, Arkadiusz Czerwonka, Marcin Bobiński, Anna Wawruszak, Rafał Tarkowski, Wiesława Bednarek, Justyna Szumiło, Jan Kotarski
    Academic press:
    Journal of Translational Medicine (rok: 2020, tom: 18, strony: 220), Wydawca: BMC Part of Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12967-020-02389-7 - link to the publication
  3. Integration of local and systemic immunity in ovarian cancer: Implications for immunotherapy
    Authors:
    Alicja Rajtak, Marta Ostrowska-Leśko, Klaudia Żak, Rafał Tarkowski, Jan Kotarski, Karolina Okła
    Academic press:
    Frontiers in Immunology (rok: 2022, tom: 13, strony: 1018256), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fimmu.2022.1018256 - link to the publication
  4. Clinical Relevance of Mortalin in Ovarian Cancer Patients
    Authors:
    Alicja Alicja Rajtak, Arkadiusz Czerwonka, Michael Pitter, Jan Kotarski, Karolina Okła
    Academic press:
    Cells (rok: 2023, tom: 12, strony: 701), Wydawca: MDPI
    Status:
    Published
    DOI:
    https://www.mdpi.com/2073-4409/12/5/701 - link to the publication

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