Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Search and characterization of bladder cancer biomarkers

2018/31/D/ST4/00109

Keywords:

mass spectrometry mass spectrometry imaging cancer biomarkers

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST4_8: Organic chemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Politechnika Rzeszowska im. Ignacego Łukasiewicza, Wydział Chemiczny

woj. podkarpackie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Joanna Nizioł 

Number of co-investigators in the project: 8

Call: SONATA 14 - announced on 2018-09-14

Amount awarded: 646 480 PLN

Project start date (Y-m-d): 2019-10-01

Project end date (Y-m-d): 2023-09-30

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Kriostat wolnostojący Leica CM1520.
  2. Zamrażarka niskotemperaturowa do -80 st.C (33 000 PLN)

Information in the final report

  • Publication in academic press/journals (12)
  • Articles in post-conference publications (1)
  1. Infrared pulsed fiber laser-produced silver-109-nanoparticles for laser desorption/ionization mass spectrometry of amino acids
    Authors:
    Aneta Płaza-Altamer, Kołodziej, Artur, Joanna Nizioł, Tomasz Ruman
    Academic press:
    Journal of Mass Spectrometry (rok: 2022, tom: 57, strony: e4815), Wydawca: Wiley Analytical Science
    Status:
    Published
    DOI:
    10.1002/jms.4815 - link to the publication
  2. Laser Ablation Synthesis in Solution and Nebulization of Silver-109 Nanoparticles for Mass Spectrometry and Mass Spectrometry Imaging
    Authors:
    Aneta Płaza, Artur Kołodziej, Joanna Nizioł, Tomasz Ruman
    Academic press:
    Measurement Science Au (rok: 2021, tom: 2, strony: 14–22), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acsmeasuresciau.1c00020 - link to the publication
  3. Targeted and untargeted urinary metabolic profiling of bladder cancer
    Authors:
    Krzysztof Ossoliński, Tomasz Ruman, Valérie Copié, Brian P. Tripet, Artur Kołodziej, Aneta Płaza-Altamer, Anna Ossolińska, Tadeusz Ossoliński, Anna Nieczaj, Joanna Nizioł
    Academic press:
    Journal of Pharmaceutical and Biomedical Analysis (rok: 2023, tom: 233, strony: 115473), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jpba.2023.115473 - link to the publication
  4. Untargeted ultra‑high‑resolution mass spectrometry metabolomic profling of blood serum in bladder cancer
    Authors:
    Joanna Nizioł, Krzysztof Ossoliński, Aneta Płaza-Altamer, Artur Kołodziej, Anna Ossolińska, Tadeusz Ossoliński, Tomasz Ruman
    Academic press:
    Scientific Reports (rok: 2022, tom: 12, strony: 15156), Wydawca: Nature Portfolio
    Status:
    Published
    DOI:
    10.1038/s41598-022-19576-9 - link to the publication
  5. Untargeted Metabolomics of Bladder Tissue using Liquid Chromatography and Quadrupole Time-of-Flight Mass Spectrometry for Cancer Biomarker Detection
    Authors:
    Joanna Nizioł, Krzysztof Ossoliński, Aneta Płaza-Altamer, Artur Kołodziej, Anna Ossolińska, Tadeusz Ossoliński, Zuzanna Krupa, Tomasz Ruman
    Academic press:
    Journal of Pharmaceutical and Biomedical Analysis (rok: 2024, ), Wydawca: Elsevier
    Status:
    Accepted for publication
    DOI:
    brak - link to the publication
  6. Monoisotopic silver nanoparticles-based mass spectrometry imaging of human bladder cancer tissue: Biomarker discovery
    Authors:
    Krzysztof Ossoliński, Tomasz Ruman, Tadeusz Ossoliński, Anna Ossolińska, Adrian Arendowski, Artur Kołodziej, Aneta Płaza Joanna Nizioł
    Academic press:
    Advances in Medical Sciences (rok: 2023, tom: 68, strony: 38-45), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.advms.2022.12.002 - link to the publication
  7. Metabolomic and elemental profiling of blood serum in bladder cancer
    Authors:
    Krzysztof Ossoliński, Tomasz Ruman, Valérie Copié, Brian P. Tripet, Leonardo B. Nogueira, Katiane O.P.C. Nogueira, Artur Kołodziej, Aneta Płaza-Altamer, Anna Ossolińska, Tadeusz Ossoliński and Joanna Nizioł
    Academic press:
    Journal of Pharmaceutical Analysis (rok: 2022, tom: 12, strony: 889-900), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jpha.2022.08.004 - link to the publication
  8. Untargeted urinary metabolomics for bladder cancer biomarker screening with ultrahigh-resolution mass spectrometry
    Authors:
    Joanna NIzioł, Krzysztof Ossoliński, Aneta Płaza-Altamer, Artur Kołodziej, Anna Ossolińska, Tadeusz Ossoliński, Anna Nieczaj, Tomasz Ruman,
    Academic press:
    Scientific Reports (rok: 2023, tom: 13, strony: 9802), Wydawca: Nature Portfolio
    Status:
    Published
    DOI:
    10.1038/s41598-023-36874-y - link to the publication
  9. Aneta Płaza-Altamer, Artur Kołodziej, Joanna Nizioł, Tomasz Ruman Laser generated gold nanoparticles for mass spectrometry of low molecular weight compounds
    Authors:
    Aneta Płaza-Altamer, Artur Kołodziej, Joanna Nizioł, Tomasz Ruman
    Academic press:
    Chemical Technology and Biotechnology (rok: 2022, tom: 1, strony: 61-69), Wydawca: Politechnika Rzeszowska im. Ignacego Łukasiewicza
    Status:
    Published
    DOI:
    10.7862/rc.2022.1 - link to the publication
  10. Infrared pulsed fiber laser-produced silver-109-nanoparticles for laser desorption/ionization mass spectrometry of 3-hydroxycarboxylic acids
    Authors:
    Kołodziej, Artur, Aneta Płaza-Altamer, Joanna Nizioł, Tomasz Ruman
    Academic press:
    Rapid Communications in Mass Spectrometry (rok: 2022, tom: 36, strony: e9375), Wydawca: Wiley Analytical Science
    Status:
    Published
    DOI:
    10.1002/rcm.9375 - link to the publication
  11. Infrared pulsed fiber laser-produced silver-109-nanoparticles for laser desorption/ionization mass spectrometry of carboxylic acids
    Authors:
    Artur Kołodziej, Aneta Płaza-Altamer, Joanna Nizioł, Tomasz Ruman
    Academic press:
    nternational Journal of Mass Spectrometry (rok: 2022, tom: 474, strony: 116816), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ijms.2022.116816 - link to the publication
  12. Metabolomic profiling of human bladder tissue extracts
    Authors:
    Krzysztof Ossoliński, Tomasz Ruman, Valérie Copié, Brian P. Tripet, Artur Kołodziej, Aneta Płaza-Altamer, Anna Ossolińska, Tadeusz Ossoliński, Zuzanna Krupa, Joanna Nizioł*
    Academic press:
    Metabolomics (rok: 2024, ), Wydawca: Springer
    Status:
    Accepted for publication
    DOI:
    brak - link to the publication
  1. Analiza metabolomiczna surowicy krwi w poszukiwaniu biomarkerów raka pęcherza moczowego
    Authors:
    J. Nizioł, K. Ossoliński, A. Płaza-Altamer, A. Kołodziej, A. Nieczaj, T. Ruman
    Conference:
    Nauka i przemysł – metody spektroskopowe w praktyce, nowe wyzwania i możliwości (rok: 2023, ), Wydawca: Wydawnictwo Uniwersytetu Marii Curie-Skłodowskiej
    Data:
    konferencja 27.06.2023
    Status:
    Published
    DOI:
    link to the publication

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