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Biphasic mechanism of electrotaxis of mouse 3T3 fibroblasts: complementary role of ion channels and chemoattractant receptors

2018/31/B/NZ3/01750

Keywords:

electrotaxis ion channels chemoattractant receptors mechanism of electrotactic reaction

Descriptors:

  • NZ3_1: Cell biology
  • NZ3_2: Cell physiology
  • NZ3_7: Signal transduction

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Zbigniew Madeja 

Number of co-investigators in the project: 4

Call: OPUS 16 - announced on 2018-09-14

Amount awarded: 1 053 682 PLN

Project start date (Y-m-d): 2019-07-05

Project end date (Y-m-d): 2024-07-04

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  • Articles in post-conference publications (2)
  • Book publications / chapters in book publications (1)
  1. Impact of elastic substrate on the dynamic heterogeneity of WC256 Walker carcinosarcoma cells
    Authors:
    Aleksandra Mielnicka, Tomasz Kołodziej, Daniel Dziob, Sławomir Lasota, Jolanta Sroka & Zenon Rajfur
    Academic press:
    Scientific Reports (rok: 2023, tom: 13, strony: 15743 (pp1-14)), Wydawca: Springer Nature © 2024 Springer Nature Limited
    Status:
    Published
    DOI:
    10.1038/s41598-023-35313-2 - link to the publication
  2. Bronchial Fibroblasts from Asthmatic Patients Display Impaired Responsiveness to Direct Current Electric Fields (dcEFs)
    Authors:
    Anastasiia Pavlenko, Sławomir Lasota, Dawid Wnuk , Milena Paw , Jarosław Czyz, Marta Michalik and Zbigniew Madeja
    Academic press:
    Biomedicines (rok: 2023, tom: 11, strony: 2138 (pp1-14)), Wydawca: MDPI, Basel, Switzerland.
    Status:
    Published
    DOI:
    10.3390/ - link to the publication
  3. The dynamics of the electrotactic reaction of mouse 3T3 fibroblasts
    Authors:
    Slawomir Lasota, Eliza Zimolag, Sylwia Bobis-Wozowicz, Jagoda Pilipiuk, Zbigniew Madeja
    Academic press:
    BBA - Molecular Cell Research (rok: 2024, tom: 1871, strony: 119647 (pp1-19)), Wydawca: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2023.119647 - link to the publication
  1. The role of EGFR redistribution in the electrotaxis of mouse 3T3 fibroblasts
    Authors:
    Sławomir Lasota, Jagoda Pilipiuk, Sylwia Bobis-Wozowicz, Ivan Cherepashuk, Zbigniew Madeja
    Conference:
    5th Congress of Polish Biosciences BIO2023 (rok: 2023, ), Wydawca: Acta Biochimica Polonica
    Data:
    konferencja 13-16 września
    Status:
    Published
  2. The rapid electrotactic response of 3T3 fibroblasts to external direct current electric fields depends on inwardly rectifying potassium channels (Kir4.2)
    Authors:
    S. Lasota, S. Bobis-Wozowicz, E. Zimolag, Z. Madeja
    Conference:
    The Biochemistry Global Summit, 25th IUBMB Congress, 46th FEBS Congress, 15th PABMB Congress, Lisbon, Portugal (rok: 2022, ), Wydawca: John Wiley & Sons, Ltd
    Data:
    konferencja July 9–14
    Status:
    Published
    DOI:
    link to the publication
  1. Lipofection-Based Delivery of DNA Vaccines
    Authors:
    Monika Rak, Anna Gora-Sochacka, and Zbigniew Madeja
    Book:
    Vaccine Delivery Technology (rok: 2021, tom: vol. 2183, strony: 391-404), Wydawca: Springer Science+Business Media, LLC, part of Springer Nature 2021
    Status:
    Published

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