Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Optimization and analysis of the biological effect of the electromagnetic field on production and the activity of bacteriophage preparations

2018/31/B/ST8/03170

Keywords:

bacteriophages bacteriophage preparations electromagnetic field production optimization

Descriptors:

  • NZ1_9: Biotechnology
  • ST8_1: Chemical engineering, technical chemistry, environmental engineering, sanitary engineering, engineering of chemical processes
  • NZ9_13: Other related subjects

Panel:

ST8 - Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution :

Zachodniopomorski Uniwersytet Technologiczny w Szczecinie, Wydział Technologii i Inżynierii Chemicznej

woj. zachodniopomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Rafał Rakoczy 

Number of co-investigators in the project: 11

Call: OPUS 16 - announced on 2018-09-14

Amount awarded: 1 742 180 PLN

Project start date (Y-m-d): 2019-08-01

Project end date (Y-m-d): 2022-12-31

Project duration:: 41 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Bioreaktor (130 000 PLN)
  2. Czytnik mikropłytek (150 000 PLN)
  3. Miernik pola magnetycznego (8 000 PLN)
  4. Instalacja badawcza wyposażona w generatory pola elektromagnetycznego (94 000 PLN)
  5. Mostek RLC (7 500 PLN)
  6. Termostat przepływowy (15 000 PLN)
  7. Urządzenie do pomiaru CO2 i O2 in-line (90 000 PLN)

Information in the final report

  • Publication in academic press/journals (14)
  • Book publications / chapters in book publications (2)
  1. Dynamic modelling of bacteriophage production process
    Authors:
    process Maciej Konopack, Bartłiomiej Grygorcewicz, Marta Gliźniewicz, Dominika Miłek, Marian Kordas, Rafał Rakoczy
    Academic press:
    Chemical and Process Engineering (rok: 2022, tom: 43 (4), strony: 471-482), Wydawca: Polish Academy of Sciences Committee of Chemical and Process Engineering
    Status:
    Published
    DOI:
    10.24425/cpe.2022.142287 - link to the publication
  2. Mathematical Modeling of Hydrodynamics in Bioreactor by Means of CFD-Based Compartment Model
    Authors:
    Krychowska A., Kordas M., Konopacki M., Grygorcewicz B., Musik D., Wójcik K., Jędrzejczak-Silicka M., Rakoczy R.
    Academic press:
    Processes (rok: 2020, tom: 8, strony: 1-12 [nr art. 1301]), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pr8101301 - link to the publication
  3. Environmental Phage-Based Cocktail and Antibiotic Combination Effects on Acinetobacter baumannii Biofilm in a Human Urine Model
    Authors:
    Grygorcewicz B., Wojciuk B., Roszak M., Łubowska N., Błażejczak P., Jursa-Kulesza J., Rakoczy R., Masiuk H., Dołęgowska B.
    Academic press:
    Microbial Drug Resistance (rok: 2021, tom: 27, strony: 25-35), Wydawca: Mary Ann Liebert, Inc.
    Status:
    Published
    DOI:
    10.1089/mdr.2020.0083 - link to the publication
  4. Growth optimization of Klebsiella pneumoniae in magnetically assisted bioreactor
    Authors:
    Konopacki M., Augustyniak A., Grygorcewicz B., Dołęgowska B., Kordas M., Rakoczy R.
    Academic press:
    Chemical and Process Engineering (rok: 2022, tom: 43 (3), strony: 289-304), Wydawca: Polish Academy of Sciences Committee of Chemical and Process Engineering
    Status:
    Published
    DOI:
    10.24425/cpe.2022.140833 - link to the publication
  5. PhageScore: A simple method for comparative evaluation of bacteriophages lytic activity
    Authors:
    Konopacki M., Grygorcewicz B., Dołęgowska B., Kordas M., Rakoczy R.
    Academic press:
    Biochemical Engineering Journal (rok: 2020, tom: 161, strony: 1-7, [nr art. 107652]), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bej.2020.107652 - link to the publication
  6. Single Mathematical Parameter for Evaluation of the Microorganisms' Growth as the Objective Function in the Optimization by the DOE Techniques
    Authors:
    Konopacki M., Augustyniak A., Grygorcewicz B., Dołęgowska B., Kordas M., Rakoczy R.
    Academic press:
    Microorganisms (rok: 2020, tom: 8, strony: 1-11, [nr art. 1706]), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/microorganisms8111706 - link to the publication
  7. Two-stage bacteriophage production process supported by the electromagnetic field
    Authors:
    Rafał Rakoczy, Maciej Konopacki, Marian Kordas, Bartłomiej Grygorcewicz
    Academic press:
    Chemical and Process Engineering (rok: 2022, tom: 43 (4), strony: 491-506), Wydawca: Polish Academy of Sciences Committee of Chemical and Process Engineering
    Status:
    Published
    DOI:
    10.24425/cpe.2022.142289 - link to the publication
  8. Effect of rotating magnetic field on ferromagnetic structures used inhyperthermia
    Authors:
    Konopacki M., Jędrzejczak-Silicka M., Szymańska K., Mijowska E., Rakoczy R.
    Academic press:
    Journal of Magnetism and Magnetic Materials (rok: 2021, tom: 518, strony: 1-8 [nr art. 167418]), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jmmm.2020.167418 - link to the publication
  9. Evaluation of ferrofluid-coated rotating magnetic field-assisted bioreactor for biomass production
    Authors:
    Jabłońska J., Augustyniak A., Kordas M., Dubrowska K., Sołoducha D., Borowski T., Konopacki M., Grygorcewicz B., Roszak M., Dołęgowska B., Piz M., Filipek E., Wróbel R. J., Leniec G., Rakoczy R.
    Academic press:
    Chemical Engineering Journal (rok: 2022, tom: 431 (2), strony: 133913), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.cej.2021.133913 - link to the publication
  10. Antibiotics act with vb_abap_agc01 phage against Acinetobacter baumannii in human heat - inactivated plasma blood and galleria mellonella models
    Authors:
    Grygorcewicz B., Roszak M., Golec P., Śleboda-Taront D., Łubkowska N., Górska M., Jursa-Kulesza J., Rakoczy R., Wojciuk B., Dołęgowska B.
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: 1-14 [nr art. 4390]), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21124390 - link to the publication
  11. Application of Magnetically Assisted Reactors for Modulation of Growth and Pyocyanin Production by Pseudomonas aeruginosa
    Authors:
    Jabłońska J., Dubrowska K., Augustyniak A., Kordas M., Rakoczy R.
    Academic press:
    Frontiers in Bioengineering and Biotechnology (rok: 2022, tom: 10, strony: 795871), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fbioe.2022.795871 - link to the publication
  12. Intensification of bacterial cellulose production process with sequential electromagnetic field exposure aided by dynamic modelling
    Authors:
    Maciej Konopacki, Bartłomiej Grygorcewicz, Marian Kordas, Paula Ossowicz-Rupniewska, Anna Nowak, Magdalena Perużyńska, Rafał Rakoczy
    Academic press:
    Biochemical Engineering Journal (rok: 2022, tom: 182, strony: 108432), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.bej.2022.108432 - link to the publication
  13. Hydrodynamics and Mass Transfer Analysis in BioFlow® Bioreactor Systems
    Authors:
    Kordas M., Konopacki M., Grygorcewicz B., Augustyniak A., Musik D., Wójcik K., Jędrzejczak-Silicka M., Rakoczy R.
    Academic press:
    Processes (rok: 2020, tom: 8, strony: 1-21, [nr art. 1311]), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pr8101311 - link to the publication
  14. Studies of a mixing process induced by a rotating magnetic field with the application of magnetic particles
    Authors:
    Rakoczy R., Kordas M., Markowska-Szczupak A., Konopacki M., Augustyniak A., Jabłonska J., Paszkiewicz O., Dubrowska K., Story G., Story A., Ziętarska K., Sołoducha D., Borowski T., Roszak M., Grygorcewicz B., Dołęgowska B.
    Academic press:
    Chemical and Process Engineering (rok: 2021, tom: 42 (2), strony: 157-172), Wydawca: Polish Academy of Sciences Committee of Chemical and Process Engineering
    Status:
    Published
    DOI:
    10.24425/cpe.2021.138922 - link to the publication
  1. The use of the electromagnetic field in microbial process bioengineering
    Authors:
    Jabłońska, J., Dubrowska, K., Gliźniewicz, M., Paszkiewicz, O., Augustyniak, A., Grygorcewicz, B., Konopacki, M., Markowska- Szczupak, A., Kordas, M., Dołęgowska, B. & Rakoczy, R.
    Book:
    ADVANCES IN APPLIED MICROBIOLOGY (rok: 2022, tom: 121, strony: 27-72), Wydawca: Elsevier
    Status:
    Published
  2. Methods of Bacteriophages Production with Application of Alternate Magnetic Field
    Authors:
    Konopacki M., Grygorcewicz B., Kordas M., Dołęgowska B., Rakoczy R.
    Book:
    Practical Aspects of Chemical Engineering. PAIC 2019 (rok: 2020, tom: nie dotyczy, strony: 171-182), Wydawca: Springer, Cham
    Status:
    Published

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