Projects funded by the NCN

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Information of the project and the call

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Role of the small non-coding RNAs in the regulation of the mechanizm of action of the repression-antirepression system associated with the life cycle switch of phages carrying dangerous to human health toxins genes

2018/30/E/NZ1/00400

Keywords:

small non-coding RNAs repression-antirepression system bacteriophages toxins lysis vs lysogeny

Descriptors:

  • NZ1_10:
  • NZ6_5:
  • NZ1_1:

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Gdański, Wydział Biologii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Bożena Nejman-Faleńczyk 

Number of co-investigators in the project: 6

Call: SONATA BIS 8 - announced on 2018-06-15

Amount awarded: 1 076 600 PLN

Project start date (Y-m-d): 2019-04-17

Project end date (Y-m-d): 2024-04-16

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  • Book publications / chapters in book publications (2)
  1. UpRoi1 - the phage-derived microRNA-size non-coding RNA molecule regulating both phage and its bacterial host development
    Authors:
    Sylwia Bloch, Natalia Lewandowska, Joanna Zwolenkiewicz-Nowak, Monika Mazur, Agnieszka Chylewska, Aleksandra M Dąbrowska, Natalia Musiał, Paulina Czaplewska, Wojciech Wesołowski, Aleksandra Łukasiak, Mariusz Ferenc, Marcin Pietrzycki, Emilia Węglińska, Paulina Mach, Grzegorz Węgrzyn, Mikołaj Olejniczak, Bożena Nejman-Faleńczyk
    Academic press:
    Biochimica et biophysica acta. Gene regulatory mechanisms (rok: 2026, tom: 1869, strony: 195135), Wydawca: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.bbagrm.2026.195135 - link to the publication
  2. Bacteriophages as sources of small non-coding RNA molecules
    Authors:
    Sylwia Bloch, Natalia Lewandowska, Grzegorz Węgrzyn, Bożena Nejman-Faleńczyk
    Academic press:
    Plasmid (rok: 2020, tom: 113, strony: 102527), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.plasmid.2020.102527 - link to the publication
  1. Application of Ultraviolet (UV) and Circular Dichroism (CD) Spectroscopies to Study RNA-RNA Interactions of Regulatory RNAs of Bacteriophage Origin
    Authors:
    Natalia Lewandowska, Sylwia Bloch, Agnieszka Chylewska, Aleksandra M Dąbrowska, Monika Mazur, Joanna Zwolenkiewicz, Wojciech Wesołowski, Aleksandra Łukasiak, Emilia Węglińska, Mikołaj Olejniczak, Grzegorz Węgrzyn, Bożena Nejman-Faleńczyk
    Book:
    RNA Spectroscopy - Methods and Protocols (Methods in Molecular Biology) (rok: 2026, tom: 3004, strony: 123-136), Wydawca: Springer Protocols (Humana Press)
    Status:
    Published
  2. Analysis of phage regulatory RNAs: sequencing library construction from the fraction of small prokaryotic RNAs less than 50 nucleotides in length.
    Authors:
    Bloch Sylwia, Lewandowska Natalia, Wesołowski Wojciech, Łukasiak Aleksandra, Mach Paulina, Nejman-Faleńczyk Bożena (koresp.),
    Book:
    Bacterial Regulatory RNA - Methods and Protocols (Methods in Molecular Biology) (rok: 2024, tom: 2714, strony: 25-34), Wydawca: Springer Protocols (Humana Press)
    Status:
    Published

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