Projects funded by the NCN

Information on the principal investigator and host institution

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Novel FUS-mediated small RNAs derived from snoRNAs: identification, biogenesis and function

2018/30/E/NZ2/00295

Keywords:

small RNAs snoRNAs FUS protein regulation of gene expression human diseases

Descriptors:

  • NZ1_1: Molecular biology
  • NZ2_1: Molecular genetics
  • NZ2_3: Proteomics

Panel:

NZ2 - Genetics, genomics: molecular genetics, genomics, proteomics, bioinformatics, systems biology, genetic epidemiology

Host institution :

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

woj. wielkopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Katarzyna Raczyńska 

Number of co-investigators in the project: 6

Call: SONATA BIS 8 - announced on 2018-06-15

Amount awarded: 3 440 900 PLN

Project start date (Y-m-d): 2019-09-18

Project end date (Y-m-d): 2024-11-17

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (6)
  1. Role of Long Intergenic Noncoding RNAs in Cancers with an Overview of MicroRNA Binding
    Authors:
    R. Pasieka, G. Zasoński, K. D. Raczyńska
    Academic press:
    Molecular Diagnosis and Therapy (rok: 2022, tom: 27(1), strony: 29-47), Wydawca: Adis
    Status:
    Published
    DOI:
    10.1007/s40291-022-00619-w - link to the publication
  2. FUS regulates a subset of snoRNA expression and modulates the level of rRNA modifications
    Authors:
    K. Gawade, P. Plewka, S.J. Häfner, A.H. Lund, V. Marchand, Y. Motorin, M.W. Szczesniak, K.D. Raczynska
    Academic press:
    Scientific Reports (rok: 2023, tom: 2,60694444444444, strony: 45309), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-023-30068-2 - link to the publication
  3. U7 snRNA: A tool for gene therapy
    Authors:
    Ankur Gadgil, Katarzyna Dorota Raczyńska
    Academic press:
    Journal of Gene Medicine (rok: 2021, tom: 23, strony: 45306), Wydawca: Wiley Online Library
    Status:
    Published
    DOI:
    10.1002/jgm.3321 - link to the publication
  4. Context-Dependent Regulation of Gene Expression by Non-Canonical Small RNAs, Noncoding RNA
    Authors:
    K. Plawgo, K. D. Raczynska
    Academic press:
    Noncoding RNA (rok: 2022, tom: 29;8(3), strony: 45321), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ncrna8030029 - link to the publication
  5. Imprinted small nucleolar RNAs: Missing link in development and disease?
    Authors:
    Gawade, K. and Raczynska K. D.
    Academic press:
    WIREs RNA (rok: 2023, tom: 1, strony: 45310), Wydawca: Wiley Interdisciplinary Reviews
    Status:
    Published
    DOI:
    10.1002/wrna.1818 - link to the publication
  6. Long Intergenic Noncoding RNAs Affect Biological Pathways Underlying Autoimmune and Neurodegenerative Disorders
    Authors:
    P. Plewka, K. D. Raczynska
    Academic press:
    Molecular Neurobioly (rok: 2022, tom: 59(9), strony: 5785-5808), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s12035-022-02941-0 - link to the publication

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