Solving the elaborated architecture of the D. radiodurans S-layer: structural analysis of its type IV-like piliation system

2018/30/M/NZ1/00284

Keywords

Descriptors

  • NZ1_4: Biologia strukturalna
  • NZ1_2: Biochemia
  • NZ1_3: Biofizyka

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Szkoła Główna Gospodarstwa Wiejskiego w Warszawie, Instytut Biologii

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Dario Piano

Number of co-investigators in the project: 4

Call

HARMONIA 10 – announced on 2018-06-15

Amount awarded
281 400 PLN
Project start date
2019-05-16
Project end date
2020-11-15
Project duration
18 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

  1. Structural insights into the main S-layer unit of Deinococcus radiodurans reveal a massive protein complex with porin-like features

    Authors:
    Domenica Farci, Mehmet Alphan Aksoyoglu, Stefano Francesco Farci, Jayesh Arun Bafna, Igor Bodrenko, Matteo Ceccarelli, Joanna Kirkpatrick, Mathias Winterhalter, Sami Kereïche, Dario Piano
    Academic press:
    Journal of Biological Chemistry (year: 2020, volume: 295, pages: 4224-4236), Publisher: American Society for Biochemistry and Molecular Biology
    Status:
    Published
    DOI:
    10.1074/jbc.RA119.012174 – link to the publication
  2. Structural analysis of the architecture and in situ localization of the main S-layer complex in Deinococcus radiodurans

    Authors:
    Domenica Farci; Sami Kereïche; Sushil Pangeni; Patrycja Haniewicz; Igor V Bodrenko; Matteo Ceccarelli; Mathias Winterhalter; Dario Piano
    Academic press:
    Structure (year: 2021, volume: 29, pages: 46029), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.str.2021.06.014 – link to the publication
  3. The cryo-EM structure of the S-layer deinoxanthin-binding complex of Deinococcus radiodurans informs properties of its environmental interactions.

    Authors:
    Domenica Farci, Patrycja Haniewicz, Daniele de Sanctis, Luca Iesu, Sami Kereïche, Mathias Winterhalter, Dario Piano.
    Academic press:
    Journal of Biological Chemistry (year: 2022, volume: 298, pages: 46030), Publisher: American Society for Biochemistry and Molecular Biology
    Status:
    Published
    DOI:
    10.1016/j.jbc.2022.102031 – link to the publication

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