Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Characterization of the role MATR3 in HIV latency and reactivation.

2018/30/E/NZ1/00874

Keywords:

HIV latency reactivation from latency post-transcriptional mechanisms MATR3

Descriptors:

  • NZ1_1: Molecular biology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Małopolskie Centrum Biotechnologii Uniwersytetu Jagiellońskiego

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Anna Kula-Pacurar 

Number of co-investigators in the project: 3

Call: SONATA BIS 8 - announced on 2018-06-15

Amount awarded: 2 304 800 PLN

Project start date (Y-m-d): 2019-04-01

Project end date (Y-m-d): 2025-03-31

Project duration:: 48 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (7)
  1. Visualization of SARS-CoV-2 using Immuno RNA-Fluorescence In Situ Hybridization
    Authors:
    Anna Kula-Pacurar1, Jakub Wadas2, Agnieszka Suder1, Artur Szczepanski1,2, Aleksandra Milewska1,2, Marek Ochman3,4, Tomasz Stacel3,4, Krzysztof Pyrc1
    Academic press:
    Journal of Visualized Experiments (rok: 2020, tom: 23, strony: 166), Wydawca: MyJoVE Corporation
    Status:
    Published
    DOI:
    10.3791/62067 - link to the publication
  2. Chalcogenium-AZT derivatives: a plausible strategy to tackle the RT-inhibitors-related oxidative stress while maintaining their anti-HIV properties.
    Authors:
    Joelma M. Sarturi, Luciano Dornelles, Natalia V. Segatto, Tiago Collares, Fabiana K. Seixas, Bruna Candia Piccoli, Fernanda D'Avila da Silva, Folorunsho Bright Omage, João Batista Teixeira da Rocha, Renata A. Balaguez, Diego Alves, Eder J. Lenardão, Eric F. Lopes, Anna Kula-Pacurar,*, Krzysztof Pyrc, Luca Sancineto, Oscar E. D. Rodrigues*
    Academic press:
    Current Medicinal Chemistry (rok: 2022, tom: 30, strony: 2449 - 2462), Wydawca: Bentham Science Publishers
    Status:
    Published
    DOI:
    10.2174/0929867329666220906095438 - link to the publication
  3. Corrigendum: Editorial: The relevance of molecular mechanisms in HIV-1 latency and reactivation from latency
    Authors:
    Pasternak AO, Rohr O, Van Lint C and Kula-Pacurar A.
    Academic press:
    Frontiers in Cellular and Infection Microbiology (rok: 2023, tom: 1, strony: 45294), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fcimb.2023.1213356 - link to the publication
  4. Current Status of Latency Reversing Agents Facing the Heterogeneity of HIV-1 Cellular and Tissue Reservoirs.
    Authors:
    Ait-Ammar A, Kula A, Darcis G, Verdikt R, De Wit S, Gautier V, Mallon PWG, Marcello A, Rohr O, Van Lint C.
    Academic press:
    Frontiers in microbiology (rok: 2020, tom: 10, strony: 3060, 1-23), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fmicb.2019.03060 - link to the publication
  5. Shocking HIV-1 with immunomodulatory latency reversing agents.
    Authors:
    Kula-Pacurar A, Rodari A,Darcis G, Van Lint C.
    Academic press:
    Seminars in Immunology (rok: 2021, tom: 51, strony: 101478), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.javascript:void(0);smim.2021.101478 - link to the publication
  6. Replication of Severe Acute Respiratory Syndrome Coronavirus 2 in Human Respiratory Epithelium
    Authors:
    Aleksandra Milewska, Anna Kula-Pacurar, Jakub Wadas, Agnieszka Suder, Artur Szczepanski, Agnieszka Dabrowska, Katarzyna Owczarek, Alessandro Marcello, Marek Ochman, Tomasz Stacel, Zenon Rajfur, Marek Sanak, Pawel Labaj, Wojciech Branicki, Krzysztof Pyrc
    Academic press:
    Journal of Virology (rok: 2020, tom: 94, strony: e00957-20), Wydawca: American Society for Microbiology
    Status:
    Published
    DOI:
    10.1128/JVI.00957-20 - link to the publication
  7. Dynamic changes in LINC00458/HBL1 lncRNA expression during hiPSC differentiation to cardiomyocytes
    Authors:
    Patrycja Maciak, Agnieszka Suder, Jakub Wadas, Faith Aronimo, Paolo Maiuri, Michał Bochenek, Krzysztof Pyrc, Anna Kula‑Pacurar & Marta Pabis
    Academic press:
    Scientific Reports (rok: 2024, tom: 14, strony: 2045-2322), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-023-49753-3 - link to the publication

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