The impact of model biological membranes on the structure and oligomerization process of human cystatin C.

2018/30/M/ST4/00039

Keywords

Descriptors

  • ST4_3: Metody spektroskopowe i spektrometryczne

Panel

ST4 – Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Voivodeship: pomorskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Paulina Czaplewska

Number of co-investigators in the project: 6

Call

HARMONIA 10 – announced on 2018-06-15

Amount awarded
843 500 PLN
Project start date
2019-04-12
Project end date
2023-04-11
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (5)

  1. DMPC Phospholipid Bilayer as a Potential Interface for Human Cystatin C Oligomerization: Analysis of Protein-Liposome Interactions Using NMR Spectroscopy

    Authors:
    Przemyslaw Jurczak, Kosma Szutkowski, Slawomir Lach, Stefan Jurga, Paulina Czaplewska,Aneta Szymanska and Igor Zhukov
    Academic press:
    Membranes (year: 2021, volume: 11, pages: 46036), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/membranes11010013 – link to the publication
  2. The Influence of the Mixed DPC:SDS Micelle on the Structure and Oligomerization Process of the Human Cystatin C

    Authors:
    Przemyslaw Jurczak, Emilia Sikorska, Paulina Czaplewska, Sylwia Rodziewicz-Motowidlo, Igor Zhukov and Aneta Szymanska
    Academic press:
    Membranes (year: 2021, volume: 11, pages: 46044), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/membranes11010017 – link to the publication
  3. Phospholipid-functionalized gold electrode for cellular membrane interface studies - interactions between DMPC bilayer and human cystatin C

    Authors:
    Paweł Niedziałkowski, Przemysław Jurczak, Marta Orlikowska, Anna Wcisło, Jacek Ryl, Tadeusz Ossowski, Paulina Czaplewska
    Academic press:
    BBA - Biomembranes (year: 2024, volume: 1866, pages: 184266), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2023.184266 – link to the publication
  4. Monomer-dimer equilibrium of human cystatin C during internalization into cancer cells

    Authors:
    Przemyslaw Jurczak, Nour Fayad, Magalie Benard, Paulina Czaplewska, Niko Hildebrandt
    Academic press:
    ChemBioChem (year: 2024, volume: -, pages: -), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1002/cbic.202400226 – link to the publication
  5. Monitoring the interactions between POPG phospholipid bilayer and amyloid-forming protein human cystatin C. Does the bilayer influence the oligomeric state and structure of the protein?

    Authors:
    Przemyslaw Jurczak, Igor Zhukov, Marta Orlikowska, Paulina Czaplewska, Emilia Sikorska
    Academic press:
    BBA - Biomembranes (year: 2024, volume: 1866, pages: 184285), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbamem.2024.184285 – link to the publication

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Graphic design and implementation: Jakub Piotrowski