Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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The role of AMP deaminase and effects of its inhibition on cardiac mitochondrial function in the experimental hypoxic and failing heart

2018/29/N/NZ4/02259

Keywords:

AMP deaminase mitochondria purine metabolism inhibition

Descriptors:

  • NZ4_11:
  • NZ4_2:

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Gdański Uniwersytet Medyczny, Wydział Lekarski

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Magdalena Agnieszka Zabielska-Kaczorowska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 15 - announced on 2018-03-15

Amount awarded: 139 760 PLN

Project start date (Y-m-d): 2019-01-31

Project end date (Y-m-d): 2023-07-30

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Beneficial Effects of RNS60 in Cardiac Ischemic Injury
    Authors:
    Magdalena A. Zabielska-Kaczorowska, Barbara Wierzbicka, Andreas Kalmes, Ewa M. Slominska, Magdi H. Yacoub, Ryszard T. Smolenski
    Academic press:
    Current Issues in Molecular Biology (rok: 2022, tom: 44, strony: 4877–4887), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cimb44100331 - link to the publication
  2. Nucleotide metabolism during experimental preservation for transplantation with Transmedium Transplant Fluid (TTF) in comparison to Histidine-Tryptophan-Ketoglutarate (HTK)
    Authors:
    Magdalena A. Zabielska-Kaczorowska, Ryszard T. Smolenski
    Academic press:
    Nucleosides, Nucleotides & Nucleic Acids (rok: 2022, tom: 41, nr 12, strony: 1386-1395), Wydawca: Taylor&Francis
    Status:
    Published
    DOI:
    10.1080/15257770.2022.2139393 - link to the publication
  3. Label‑free quantitative SWATH‑MS proteomic analysis of adult myocardial slices in vitro after biomimetic electromechanical stimulation
    Authors:
    M. A. Zabielska‑Kaczorowska, A. E. Bogucka, K. Macur, P. Czaplewska, S. A. Watson, F. Perbellini, C. M. Terracciano, R. T. Smolenski
    Academic press:
    Scientific Reports (rok: 2022, tom: 12, strony: 16533), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41598-022-20494-z - link to the publication
  4. Hidden pool of cardiac adenine nucleotides that controls adenosine production
    Authors:
    Zabielska-Kaczorowska Magdalena ; Braczko Alicja ; Pelikant-Małecka Iwona ; Słomińska Ewa ; Smoleński Ryszard Tomasz
    Academic press:
    Pharmaceuticals (rok: 2023, tom: vol. 16, nr3, strony: 45670), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ph16040599 - link to the publication

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