Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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Comprehensive evaluation of cytokine profile in exposure of human milk to environmental and diet factors with specialized analytical tools

2018/29/B/ST4/01681

Keywords:

proinflammatory cytokines human breast milk magnetic molecularly imprinted polymers matrix assisted laser desorption ionization-time of flight mass spectrometry

Descriptors:

  • ST4_6: Instrumental methods in chemistry
  • ST4_18: Radiation and nuclear chemistry
  • NZ7_15: Toxicology

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Mikołaja Kopernika w Toruniu, Wydział Chemii

woj. kujawsko-pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Renata Gadzała-Kopciuch 

Number of co-investigators in the project: 6

Call: OPUS 15 - announced on 2018-03-15

Amount awarded: 651 100 PLN

Project start date (Y-m-d): 2019-01-24

Project end date (Y-m-d): 2022-04-23

Project duration:: 39 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Zakup nowego lasera DPSS do MALDI (Bruker) (149 999 PLN)
  2. Reaktor ciśnieniowy z głowicą wyposażoną w manometr oraz dopływ gazu obojętnego do syntezy wraz z naczyniami o pojemności 10 i 25 ml (23 000 PLN)

Information in the final report

  • Publication in academic press/journals (9)
  • Book publications / chapters in book publications (1)
  1. A novel non-derivatization HPLC/UV method for the determination of some n-3 free fatty acids in breast milk matrix
    Authors:
    Kiełbasa A., Buszewski B., Gadzała-Kopciuch R.
    Academic press:
    Microchemical Journal (rok: 2022, tom: 181, strony: 107789), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.microc.2022.107789 - link to the publication
  2. An analysis of IL-8, IL-6, TNF-α cytokines in breast milk and the relationship between milk nutrients and clinical diagnosis
    Authors:
    Renata Gadzała-Kopciuch, Anna Kuźniewska-Radke, Viorica Railean, Paweł Pomastowski, Urszula Bernatowicz-Łojko, Elena Sinkiewicz-Darol, Bogusław Buszewski
    Academic press:
    Journal of Food Composition and Analysis (rok: 2023, tom: 124, strony: 105731), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jfca.2023.105731 - link to the publication
  3. Carbon dots as rapid assays for detection of mercury(II) ions based on turn-off mode and breast milk
    Authors:
    Pajewska-Szmyt M., Buszewski B., Gadzała-Kopciuch R.
    Academic press:
    Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy (rok: 2020, tom: 236, strony: 118320(1-8)), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.saa.2020.118320 - link to the publication
  4. Cytokines-Biogenesis and Their Role in Human Breast Milk and Determination
    Authors:
    Kiełbasa A., Gadzała-Kopciuch R., Buszewski B.
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22(12), strony: 45309), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22126238 - link to the publication
  5. Supported ionic liquid adsorbent and ELSD–HPLC method as an alternative procedure for exogenous fatty acid analysis in breast milk
    Authors:
    Pajewska-Szmyt M., Buszewski B., Gadzała-Kopciuch R.
    Academic press:
    Microchemical Journal (rok: 2020, tom: 157, strony: 104961 (1-7)), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.microc.2020.104961 - link to the publication
  6. Sulphur and nitrogen doped carbon dots synthesis by microwave assisted method as quantitative analytical nano-tool for mercury ion sensing
    Authors:
    Pajewska-Szmyt M., Buszewski B., Gadzała-Kopciuch R.
    Academic press:
    Materials Chemistry and Physics (rok: 2020, tom: 242, strony: https://doi.org/10.1016/j.matchemphys.2019.122484), Wydawca: ScienceDirect
    Status:
    Published
    DOI:
    10.1016/j.matchemphys.2019.122484 - link to the publication
  7. QuEChERS extraction coupled to GC-MS for a fast determination of polychlorinated biphenyls in breast milk from Polish women
    Authors:
    Pajewska-Szmyt, M, Sinkiewicz-Darol, E., Bernatowicz-Łojko, U., Kowalkowski, T., Gadzała-Kopciuch, R., Buszewski, B
    Academic press:
    Environmental Science and Pollution Research (rok: 2019, tom: 26 (30), strony: https://doi.org/10.1007/s11356-019-06201-y), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s11356-019-06201-y - link to the publication
  8. Synthesis of magnetic molecularly imprinted polymer sorbents for isolation of parabens from breast milk
    Authors:
    Pajewska-Szmyt M., Biniewska E., Buszewski B., Gadzała-Kopciuch R.
    Academic press:
    Materials (rok: 2020, tom: 13, strony: 4328 (1-18)), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma13194328 - link to the publication
  9. The content of selected omega-3 free fatty acids in breast milk samples
    Authors:
    Kiełbasa A., Monedeiro F., Berantowicz-Łojko U., Sinkiewicz-Darol E., Buszewski B., Gadzała-Kopciuch R.
    Academic press:
    International Dairy Journal (rok: 2024, tom: 148, strony: 105803), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.idairyj.2023.105803 - link to the publication
  1. Human Milk and Xenobiotics
    Authors:
    R. Gadzała-Kopciuch, M. Pajewska-Szmyt
    Book:
    Bioanalysis as a Source of Information for Diagnosis, Medical Therapy, and Forensic Purposes (rok: 2022, tom: I, strony: 295-308), Wydawca: Springer
    Status:
    Accepted for publication

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