Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Role of different alleles of peptidylarginine deiminase from Porphyromonas gingivalis in periodontitis.

2018/29/N/NZ1/00992

Keywords:

Periodontitis citrullination peptidylarginine deiminase molecular genetics

Descriptors:

  • NZ1_10: Microbiology
  • NZ1_1: Molecular biology
  • NZ6_4: Bacteriology

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Grzegorz Bereta 

Number of co-investigators in the project: 2

Call: PRELUDIUM 15 - announced on 2018-03-15

Amount awarded: 139 300 PLN

Project start date (Y-m-d): 2019-02-04

Project end date (Y-m-d): 2022-02-03

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Zakup licencji na program do analizy sekwencji SnapGene (3 500 PLN)
  2. Mieszadło magnetyczne (430 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Citrullinome of Porphyromonas gingivalis Outer Membrane Vesicles: Confident Identification of Citrullinated Peptides
    Authors:
    Daniel Nyberg Larsen, Christian Engelbrecht Mikkelsen, Mads Kierkegaard, Grzegorz P. Bereta, Zuzanna Nowakowska, Jakub Z. Kaczmarek, Jan Potempa, and Peter Højrup
    Academic press:
    Molecular & Cellular Proteomics (rok: 2020, tom: 19, strony: 167-180), Wydawca: American Society of Biochemistry and Molecular Biology, Inc.
    Status:
    Published
    DOI:
    10.1074/mcp.RA119.001700 - link to the publication
  2. Structure, function, and inhibition of a genomic/clinical variant of Porphyromonas gingivalis peptidylarginine deiminase
    Authors:
    Grzegorz Bereta, Theodoros Goulas, Mariusz Madej, Ewa Bielecka, Maria Solà, Jan Potempa and F. Xavier Gomis-Rüth
    Academic press:
    Protein Science (rok: 2019, tom: 28, strony: 478-486), Wydawca: Wiley, The Protein Society
    Status:
    Published
    DOI:
    10.1002/pro.3571 - link to the publication
  3. TLR2 activation by Porphyromonas gingivalis requires both PPAD activity and fimbriae
    Authors:
    Aleksandra Wielento, Grzegorz P Bereta, Katarzyna B Łagosz-Ćwik, Sigrun Eick, Richard Lamont, Aleksander M Grabiec, Jan Potempa
    Academic press:
    Frontiers in Immunology (rok: 2022, tom: 13, strony: 823685), Wydawca: Frontiers Media
    Status:
    Published
    DOI:
    10.3389/fimmu.2022.823685 - link to the publication

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