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RS-SRS-MED: Spontaneous and stimulated Raman scattering microscopy for sensitive and ultrafast imaging of cells upon development of life style diseases

2018/29/B/ST4/00335

Keywords:

Raman spectroscopy imaging spontaneous and simulated spectroscopy cells tissues

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST4_13: Solid-state chemistry, surface physicochemistry
  • ST4_6: Instrumental methods in chemistry

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Uniwersytet Jagielloński, Wydział Chemii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Małgorzata Barańska 

Number of co-investigators in the project: 8

Call: OPUS 15 - announced on 2018-03-15

Amount awarded: 1 896 400 PLN

Project start date (Y-m-d): 2019-01-31

Project end date (Y-m-d): 2024-01-30

Project duration:: 36 months (the same as in the proposal)

Project status: Project completed

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (11)
  • Book publications / chapters in book publications (1)
  1. Astaxanthin as a new Raman probe for biosensing of specific subcellular lipidic structures: can we detect lipids in cells under resonance conditions?
    Authors:
    Krzysztof Czamara, Adriana Adamczyk, Marta Stojak, Basseem Radwan, Malgorzata Baranska
    Academic press:
    Cellular and Molecular Life Sciences (rok: 2020, tom: b.d., strony: 45299), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00018-020-03718-1 - link to the publication
  2. Changes in the mitochondrial membrane potential in endothelial cells can be detected by Raman microscopy
    Authors:
    A. Pieczara, E. Matuszyk, P. Szczesniak, J. Mlynarski, M. Baranska
    Academic press:
    Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy (rok: 2023, tom: 286, strony: 45300), Wydawca: Science Direct
    Status:
    Published
    DOI:
    10.1016/j.saa.2022.121978 - link to the publication
  3. Uptake and anti-inflammatory effects of liposomal astaxanthin on endothelial cells tracked by Raman and fluorescence imaging
    Authors:
    Basseem Radwan, Amrutha Prabhakaran, Stefano Rocchetti, Ewelina Matuszyk, Tia E. Keyes, Malgorzata Baranska
    Academic press:
    Microchimica Acta (rok: 2023, tom: 190, strony: 45300), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00604-023-05888-8 - link to the publication
  4. Raman microscopy reveals how cell inflammation activates glucose and lipid metabolism
    Authors:
    Aleksandra Borek-Dorosz, Anna Pieczara, Jagoda Orleanska, Krzysztof Brzozowski, William Tipping, Duncan Graham, Ewelina Bik, Adam Kubrak, Malgorzata Baranska, Katarzyna Majzner
    Academic press:
    Biochimica et Biophysica Acta (BBA) - Molecular Cell Research (rok: 2024, tom: 1871, strony: 45303), Wydawca: Science Direct
    Status:
    Published
    DOI:
    10.1016/j.bbamcr.2023.119575 - link to the publication
  5. What is the ability of inflamed endothelium to uptake exogenous saturated fatty acids? A proof-of-concept study using spontaneous Raman, SRS and CARS microscopy
    Authors:
    A. Borek-Dorosz, A. Pieczara, K. Czamara, Marta S., E. Matuszyk, K. Majzner, K. Brzozowski, A. Bresci, D. Polli, M. Baranska
    Academic press:
    Cellular and Molecular Life Sciences (rok: 2022, tom: 79, strony: 45306), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00018-022-04616-4 - link to the publication
  6. Differential response of Liver Sinusoidal Endothelial Cells and hepatocytes to oleic and palmitic acid revealed by Raman and CARS imaging
    Authors:
    Ewelina Matuszyk; Ewa Sierka; Marko Rodewald; Hyeonsoo Bae; Tobias Meyer; Edyta Kus; Stefan Chlopicki; Michael Schmitt; Jürgen Popp; Malgorzata Baranska
    Academic press:
    BBA-Molecular Basis of Disease (rok: 2020, tom: 1866, strony: 45302), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbadis.2020.165763 - link to the publication
  7. EdU sensing: the Raman way of following endothelial cell proliferation in vitro and ex vivo
    Authors:
    B. Radwan, S. Rocchetti, E. Matuszyk, M. Sternak, M. Stodulski, R. Pawlowski, J. Mlynarski, K. Brzozowski, S. Chlopicki, M. Baranska
    Academic press:
    Biosensors and Bioelectronics (rok: 2022, tom: 216, strony: 45300), Wydawca: Science Direct
    Status:
    Published
    DOI:
    10.1016/j.bios.2022.114624 - link to the publication
  8. Modified glucose as a sensor to track the metabolism of individual living endothelial cells - Observation of the 1602 cm−1 band called Raman spectroscopic signature of life"
    Authors:
    Anna Pieczara, Aleksandra Borek-Dorosz, Szymon Buda, William Tipping, Duncan Graham, Robert Pawlowski, Jacek Mlynarski, Malgorzata Baranska
    Academic press:
    Biosensors and Bioelectronics (rok: 2023, tom: 230, strony: 45300), Wydawca: Science Direct
    Status:
    Published
    DOI:
    10.1016/j.bios.2023.115234 - link to the publication
  9. Stimulated Raman Scattering Microscopy in Chemistry and Life Science – Development, Innovation, Perspective
    Authors:
    K. Brzozowski, E. Matuszyk, A. Pieczara, J. Firlej, A. Nowakowska, M. Baranska
    Academic press:
    Biotechnology Advances (rok: 2022, tom: 60, strony: 45303), Wydawca: Science Direct
    Status:
    Published
    DOI:
    10.1016/j.biotechadv.2022.108003 - link to the publication
  10. Estimation of the content of lipids composing endothelial lipid droplets based on Raman imaging
    Authors:
    Marta Z.Pacia, Katarzyna Majzner, Krzysztof Czamara, Magdalena Sternak, Stefan Chlopicki, Malgorzata Baranska
    Academic press:
    Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids (rok: 2020, tom: 1865, strony: 45301), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bbalip.2020.158758 - link to the publication
  11. Labeled vs. Label-Free Raman Imaging of Lipids in Endothelial Cells of Various Origins
    Authors:
    Basseem Radwan, Adriana Adamczyk, Szymon Tott, Krzysztof Czamara, Katarzyna Kaminska, Ewelina Matuszyk, Malgorzata Baranska
    Academic press:
    Molecules (rok: 2020, tom: 25, strony: 45300), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/molecules25235752 - link to the publication
  1. Vibrational imaging of proteins: changes in the tissues and cells in the lifestyle disease studies
    Authors:
    K. Majzner, K. Czamara, M.Z. Pacia, J. Dybaś, E. Bik, K. Chrąbaszcz, E. Bik, K. Chrabąszcz, E. Wiercigroch, A. Dorosz, A. Wisłocka, K. M. Marzec, K. Małek, M. Barańska
    Book:
    Vibrational Spectroscopy in Protein Research (rok: 2020, tom: 1, strony: 14977), Wydawca: Elsevier
    Status:
    Accepted for publication

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