Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Bifunctional silica composites for bone tissue - therapeutic and regenerative implication

2018/29/B/NZ7/00533

Keywords:

mesoporous silica materials bioglass hydroxyapatite drugs osteoblasts cells osteosarcoma cells

Descriptors:

  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Gdański Uniwersytet Medyczny, Wydział Farmaceutyczny

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Magdalena Prokopowicz 

Number of co-investigators in the project: 4

Call: OPUS 15 - announced on 2018-03-15

Amount awarded: 666 480 PLN

Project start date (Y-m-d): 2019-01-24

Project end date (Y-m-d): 2023-07-23

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. laptop (5 800 PLN)
  2. Analizator Tekstury (120 000 PLN)

Information in the final report

  • Publication in academic press/journals (7)
  • Articles in post-conference publications (1)
  1. Bioglass obtained via one-pot synthesis as osseointegrative drug delivery system
    Authors:
    Autorzy: SKWIRA ADRIANNA, SZEWCZYK ADRIAN, SĄDEJ RAFAŁ, PROKOPOWICZ MAGDALENA.
    Academic press:
    International Journal of Pharmaceutics (rok: 2023, tom: 633, strony: 45306), Wydawca: Elsevier B.V.
    Status:
    Published
    DOI:
    10.1016/j.ijpharm.2023.122610 - link to the publication
  2. Biphasic composite of calcium phosphate-based mesoporous silica as a novel bone drug delivery system
    Authors:
    Magdalena Prokopowicz, Adrian Szewczyk, Adrianna Skwira, Rafał Sądej, Gavin Walker
    Academic press:
    Drug Delivery and Translational Research (rok: 2020, tom: 10, strony: 455-470), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s13346-019-00686-3 - link to the publication
  3. Mesoporous silica-bioglass composite pellets as bone drug delivery system with mineralization potential
    Authors:
    Adrian Szewczyk, Adrianna Skwira, Agnieszka Konopacka, Rafał Sądej, Magdalena Prokopowicz*
    Academic press:
    International Journal of Molecular Science (rok: 2021, tom: 22, strony: 45311), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22094708 - link to the publication
  4. Mesoporous silica pellets as bifunctional bone drug delivery system for cefazolin
    Authors:
    Adrian Szewczyk, Adrianna Skwira, Agnieszka Konopacka, Rafał Sądej, Gavin Walker, Magdalena Prokopowicz⁎
    Academic press:
    International Journal of Pharmaceutics (rok: 2020, tom: 588, strony: 45303), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ijpharm.2020.119718 - link to the publication
  5. Microwave-Assisted Fabrication of Mesoporous Silica-Calcium Phosphate Composites for Dental Application
    Authors:
    Adrian Szewczyk, Adrianna Skwira, Marta Ginter, Donata Tajer and Magdalena Prokopowicz *
    Academic press:
    Polymers (rok: 2021, tom: 13(1), strony: 45308), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/polym13010053 - link to the publication
  6. The effect of polydimethylsiloxane-ethylcellulose coating blends on the surface characterization and drug release of ciprofloxacin-loaded mesoporous silica
    Authors:
    SKWIRA ADRIANNA, SZEWCZYK ADRIAN, PROKOPOWICZ MAGDALENA.
    Academic press:
    Polymers (rok: 2019, tom: 11, strony: 45306), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/polym11091450 - link to the publication
  7. Silica-polymer composites as the novel antibiotic delivery systems for bone tissue infection
    Authors:
    SKWIRA ADRIANNA, SZEWCZYK ADRIAN, Konopacka Agnieszka, Górska Monika, Majda Dorota, SĄDEJ RAFAŁ, PROKOPOWICZ MAGDALENA.
    Academic press:
    Pharmaceutics (rok: 2020, tom: 12, strony: 45311), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics12010028 - link to the publication
  1. Drug-loaded mesoporous silica/calcium phosphate composites for bone regeneration
    Authors:
    SZEWCZYK ADRIAN, SKWIRA ADRIANNA, PROKOPOWICZ MAGDALENA
    Conference:
    IMPLANTS 2019 (rok: 2019, ), Wydawca: Polish Society for Biomaterialsin Krakow/PolskieStowarzyszenie Biomateriałóww Krakowie
    Data:
    konferencja 28-29 CZERWIEC
    Status:
    Published
    DOI:
    link to the publication

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