Contribution of PHLDA1 to response of neuroblastoma cells to clinical and experi

Contribution of PHLDA1 to response of neuroblastoma cells to clinical and experimental ways of treatment of high-risk neuroblastoma

2018/29/B/NZ7/01564

Keywords

Descriptors

NZ7_14: Farmacja, farmakoterapia, farmakologia
NZ1_1: Biologia molekularna
NZ3_7: Przekaźnictwo sygnału

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Hanna Barbara Rokita

Number of co-investigators in the project: 6

Call

OPUS 15 – announced on 2018-03-15

Amount awarded: 1 342 400 PLN
Project start date: 2019-01-28
Project end date: 2024-01-27
Project duration: 60 months (the same as in the proposal)
Project status: Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (3)

Silencing of the PHLDA1 leads to global proteome changes and differentiation pathways of human neuroblastoma cells

Authors:
Beata Bugara, Małgorzata Durbas, Maja Kudrycka, Agata Malinowska, Irena Horwacik, Hanna Rokita

Academic press:
Frontiers in Pharmacology (year: 2024, volume: 15, pages: 46038), Publisher: Frontiers

Status:
Published
The extracellular matrix and neuroblastoma cell communication - a complex interplay and its therapeutic implications

Authors:
Irena Horwacik

Academic press:
Cells (year: 2022, volume: 11, pages: 3172), Publisher: MDPI

Status:
Published

DOI:
10.3390/cells11193172 – link to the publication
Apoptosis is responsible for cytotoxic effects of anti-GD2 ganglioside antibodies and aurora A kinase inhibitors on human neuroblastoma cells

Authors:
Małgorzata Durbas, Hanna Rokita, Irena Horwacik, Aneta Wiśniewska, Iwona Nowak

Academic press:
Acta Biochimica Polonica (year: 2022, volume: 69, pages: 485-494), Publisher: Polish Biochemical Society and the Committee of Biochemistry and Biophysics of Polish Academy of Sciences

Status:
Published

DOI:
10.18388/abp.2020-6344 – link to the publication

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