Do natural products of plant origin support the therapy of urinary tracts infections (UTIs)?

2018/29/B/NZ7/01873

Keywords

Descriptors

  • NZ7_14: Farmacja, farmakoterapia, farmakologia
  • NZ7_12: Prewencja chorób człowieka
  • NZ7_16: Inne zagadnienia pokrewne

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Sebastian Granica

Number of co-investigators in the project: 6

Call

OPUS 15 – announced on 2018-03-15

Amount awarded
1 692 000 PLN
Project start date
2019-01-31
Project end date
2023-01-30
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (4)

  1. High molecular pyrogens present in plant extracts interfere with examinations of their immunomodulatory properties in vitro

    Authors:
    Aleksandra Kruk, Jakub P. Piwowarski, Karolina A. Pawłowska, Dominik Popowski, Sebastian Granica
    Academic press:
    Scientific Reports (year: 2020, volume: 11, pages: 799), Publisher: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-020-79579-2 – link to the publication
  2. Gut Microbiota of Pigs Metabolizes Extracts of Filipendula ulmaria and Orthosiphon aristatus–Herbal Remedies Used in Urinary Tract Disorders

    Authors:
    Dominik Popowski, Jurgen Zentek, Jakub P. Piwowarski, Sebastian Granica
    Academic press:
    Planta Medica (year: 2021, volume: 2021, pages: 46030), Publisher: Theime
    Status:
    Published
    DOI:
    10.1055/a-1647-2866 – link to the publication
  3. Gut microbiota metabolism and the permeability of natural products contained in infusions from herb of European goldenrod Solidago virgaurea L.

    Authors:
    Dominik Popowski, Monika E.Czerwińska, Aleksandra Kruk, Karolina A.Pawłowska, Jürgen Zentek, Matthias F.Melzig, Jakub P.Piwowarski, Sebastian Granica
    Academic press:
    Journal of Ethnopharmacology (year: 2021, volume: 273, pages: 113924), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jep.2021.113924 – link to the publication
  4. Antiadhesive activity of hydroethanolic extract from bean pods of Phaseolus vulgaris (common bean) against uropathogenic E. coli and permeability of its constituents through Caco-2 cells monolayer

    Authors:
    Dominik Popowski, Karolina A. Pawłowska, Melanie Deipenbrock, Andreas Hensel, Aleksandra Kruk, Matthias F. Melzig, Jakub P. Piwowarski, Sebastian Granica
    Status:
    Accepted for publication

Articles in post-conference publications (3)

  1. Phytochemical analysis, metabolism, anti-adhesive and anti-inflammatory activity of infusion from silver birch leaves (Betula pendula Roth)

    Authors:
    K Pawłowska , D Popowski , A Kruk , J Piwowarski , S Granica∗
    Conference:
    70th Annual Meeting of GA (year: 2022, pages: 1549), Publisher: Thieme
    Date:
    conference 28-31.08.2022
    Status:
    Published
  2. Silver birch (Betula pendula Roth) – phytochemical characterization of the constituents and their metabolites present in the urine

    Authors:
    D Popowski , M Korczak , KA Pawłowska , A Kruk , JP Piwowarski , S Granica
    Conference:
    69th Annual Meeting of GA (year: 2021, pages: 1250-1251), Publisher: Thieme
    Date:
    conference 5-8.09.2021
    Status:
    Published
  3. Main non-flavonoid constituent of birch leaves water extract – 3-hydroxy-1-(4-hydroxyphenyl)-propan-1-one 3-O-β-D-glucoside: isolation, permeability, and antiadhesive activity

    Authors:
    D Popowski∗ , W Skowrońska , M Korczak , A Kruk , K Pawłowska , J Piwowarski , S Granica
    Conference:
    70th Annual Meeting of GA (year: 2022, pages: 1468-1469), Publisher: Thieme
    Date:
    conference 28-31.08.2022
    Status:
    Published

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Graphic design and implementation: Jakub Piotrowski