Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

Delete all

Do natural products of plant origin support the therapy of urinary tracts infections (UTIs)?

2018/29/B/NZ7/01873

Keywords:

urinary tracts infections natural products medicinal plants gut microbiota

Descriptors:

  • NZ7_14:
  • NZ7_12:
  • NZ7_16:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Farmaceutyczny

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Sebastian Granica 

Number of co-investigators in the project: 6

Call: OPUS 15 - announced on 2018-03-15

Amount awarded: 1 692 000 PLN

Project start date (Y-m-d): 2019-01-31

Project end date (Y-m-d): 2023-01-30

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (5)
  • Articles in post-conference publications (3)
  1. Gut microbiota metabolism and the permeability of natural products contained in infusions from herb of European goldenrod Solidago virgaurea L.
    Authors:
    Dominik Popowski, Monika E.Czerwińska, Aleksandra Kruk, Karolina A.Pawłowska, Jürgen Zentek, Matthias F.Melzig, Jakub P.Piwowarski, Sebastian Granica
    Academic press:
    Journal of Ethnopharmacology (rok: 2021, tom: 273, strony: 113924), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.jep.2021.113924 - link to the publication
  2. Gut Microbiota of Pigs Metabolizes Extracts of Filipendula ulmaria and Orthosiphon aristatus–Herbal Remedies Used in Urinary Tract Disorders
    Authors:
    Dominik Popowski, Jurgen Zentek, Jakub P. Piwowarski, Sebastian Granica
    Academic press:
    Planta Medica (rok: 2021, tom: 2021, strony: 45665), Wydawca: Theime
    Status:
    Published
    DOI:
    10.1055/a-1647-2866 - link to the publication
  3. High molecular pyrogens present in plant extracts interfere with examinations of their immunomodulatory properties in vitro
    Authors:
    Aleksandra Kruk, Jakub P. Piwowarski, Karolina A. Pawłowska, Dominik Popowski, Sebastian Granica
    Academic press:
    Scientific Reports (rok: 2020, tom: 11, strony: 799), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-020-79579-2 - link to the publication
  4. High molecular pyrogens present in plant extracts interfere with examinations of their immunomodulatory properties in vitro
    Authors:
    Aleksandra Kruk, Jakub P. Piwowarski, Karolina A. Pawłowska, Dominik Popowski, Sebastian Granica
    Academic press:
    Scientific Reports (rok: 2020, tom: 11, strony: 799), Wydawca: Nature
    Status:
    Published
    DOI:
    10.1038/s41598-020-79579-2 - link to the publication
  5. Antiadhesive activity of hydroethanolic extract from bean pods of Phaseolus vulgaris (common bean) against uropathogenic E. coli and permeability of its constituents through Caco-2 cells monolayer
    Authors:
    Dominik Popowski, Karolina A. Pawłowska, Melanie Deipenbrock, Andreas Hensel, Aleksandra Kruk, Matthias F. Melzig, Jakub P. Piwowarski, Sebastian Granica
    Status:
    Accepted for publication
  1. Main non-flavonoid constituent of birch leaves water extract – 3-hydroxy-1-(4-hydroxyphenyl)-propan-1-one 3-O-β-D-glucoside: isolation, permeability, and antiadhesive activity
    Authors:
    D Popowski∗ , W Skowrońska , M Korczak , A Kruk , K Pawłowska , J Piwowarski , S Granica
    Conference:
    70th Annual Meeting of GA (rok: 2022, ), Wydawca: Thieme
    Data:
    konferencja 28-31.08.2022
    Status:
    Published
  2. Silver birch (Betula pendula Roth) – phytochemical characterization of the constituents and their metabolites present in the urine
    Authors:
    D Popowski , M Korczak , KA Pawłowska , A Kruk , JP Piwowarski , S Granica
    Conference:
    69th Annual Meeting of GA (rok: 2021, ), Wydawca: Thieme
    Data:
    konferencja 5-8.09.2021
    Status:
    Published
  3. Phytochemical analysis, metabolism, anti-adhesive and anti-inflammatory activity of infusion from silver birch leaves (Betula pendula Roth)
    Authors:
    K Pawłowska , D Popowski , A Kruk , J Piwowarski , S Granica∗
    Conference:
    70th Annual Meeting of GA (rok: 2022, ), Wydawca: Thieme
    Data:
    konferencja 28-31.08.2022
    Status:
    Published