Projektowanie, synteza i badanie właściwości adeninowych nukleotydowych sond fluorescencyjnych - narzędzie do monitorowania reakcji enzymatycznych

2018/28/T/ST5/00109

Descriptors

  • NZ1_3: Biofizyka
  • ST5_16: Chemia biologiczna
  • ST5_23: Chemia organiczna

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

Uniwersytet Warszawski, Wydział Fizyki

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

Przemysław Marek Wanat

Number of co-investigators in the project: 2

Call

ETIUDA 6 – announced on 2017-12-15

Amount awarded
112 135 PLN
Project start date
2018-10-01
Project end date
2019-09-30
Project duration
12 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (2)

  1. A New 1,5-Disubstituted Triazole DNA Backbone Mimic with Enhanced Polymerase Compatibility

    Authors:
    Sven Epple, Aman Modi, Ysobel R. Baker, Ewa Wȩgrzyn, Diallo Traoré, Przemyslaw Wanat, Agnes E. S. Tyburn, Arun Shivalingam, Lapatrada Taemaitree, Afaf H. El-Sagheer, and Tom Brown
    Academic press:
    J. Am. Chem. Soc. (year: 2021, volume: 143, pages: 16293–16301), Publisher: ACS Publications
    Status:
    Published
    DOI:
    10.1021/jacs.1c08057 – link to the publication
  2. Searching for the ideal triazole: Investigating the 1,5-triazole as a charge neutral DNA backbone mimic

    Authors:
    Ysobel R.Baker, Diallo Traoré, Przemyslaw Wanat, Agnès Tyburn, Afaf H.El-Sagheer, TomBrown
    Academic press:
    Tetrahedron (year: 2020, volume: 76,7, pages: 130914), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.tet.2019.130914 – link to the publication

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