Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The effect of physical activity on the tissue nitric oxide (NO) bioavailability and mitochondrial biogenesis in skeletal muscle and in the heart of the transgenic mice (Tgalfaq*44) with chronic heart failure.

2017/27/B/NZ7/01976

Keywords:

physical activity endurance training mitochondrial biogenesis nitric oxide nitrite heart failure

Descriptors:

  • NZ7_3: Physical culture and health promotion

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Uniwersytet Jagielloński, Collegium Medicum

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Joanna Majerczak 

Number of co-investigators in the project: 8

Call: OPUS 14 - announced on 2017-09-15

Amount awarded: 1 088 329 PLN

Project start date (Y-m-d): 2018-09-20

Project end date (Y-m-d): 2023-03-19

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Aparat do elektroforezy żelowej i transferu białek z zasilaczem-Mini-PROTEAN Tetra Cell and Mini Trans-Blot Module, Mini Trans-Blot Electrophoretic Transfer Cell, PowerPac Basic Power Supply, Bio-Rad (20 000 PLN)
  2. Ultra-Micro elektroda pH (1 336 PLN)
  3. Wytrząsarka kołyskowa (2 szt.) (5 000 PLN)
  4. Aparat do elektroforezy żelowej (Mini-PROTEAN Tetra Cell) firmy BioRad..
  5. Mikser próbek i pionowy rotator z obrotową, pionową zmienną prędkością, łączącą wibracje, pochylenie i obracanie próbki HulaMixer Sample Mixer (4 000 PLN)
  6. wirówka laboratoryjna mini spin.
  7. Elektroniczna pipeta ośmiokanałowa (5-100 μl) wraz z akcesoriami (8 500 PLN)
  8. pHmetr stacjonarny, elektorniczny.

Information in the final report

  • Publication in academic press/journals (5)
  1. Characterization of age-dependent decline in spontaneous running performance in the heart failure Tgαq*44 mice
    Authors:
    Jerzy A. Żołądź, Zenon Nieckarz, Zbigniew Szkutnik, Elżbieta Pyza, Stefan Chłopicki, Joanna Majerczak
    Academic press:
    Journal of Physiology and Pharmacology (rok: 2021, tom: 72, strony: 259-271), Wydawca: The Polish Physiological Society
    Status:
    Published
    DOI:
    10.26402/jpp.2021.2.11. - link to the publication
  2. The impact of aging and physical training on angiogenesis in the musculoskeletal system.
    Authors:
    Magdalena Żmudzka, Jerzy A. Żołądź, Joanna Majerczak
    Academic press:
    PeerJ (rok: 2022, tom: 10, strony: e14228), Wydawca: PeerJ Inc
    Status:
    Published
    DOI:
    10.7717/peerj.14228 - link to the publication
  3. Nitrite Concentration in the Striated Muscles Is Reversely Related to Myoglobin and Mitochondrial Proteins Content in Rats
    Authors:
    Joanna Majerczak, Agnieszka Kij, Hanna Drzymała-Celichowska, Kamil Kuś, Janusz Karasiński, Zenon Nieckarz, Marcin Grandys, Jan Celichowski, Zbigniew Szkutnik, Ulrike B Hendgen-Cotta , Jerzy A. Żołądź
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 2686), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23052686 - link to the publication
  4. Impact of long-lasting spontaneous physical activity on bone morphogenetic protein 4 in the heart and tibia in murine model of heart failure
    Authors:
    Joanna Majerczak, Joanna Filipowska, Grzegorz Tylko, Magdalena Guzik, Janusz Karasiński, Ewa Piechowicz, Elżbieta Pyza, Stefan Chłopicki, Jerzy A. Żołądź
    Academic press:
    Physiological Reports (rok: 2020, tom: 8, strony: e14412), Wydawca: Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.
    Status:
    Published
    DOI:
    10.14814/ - link to the publication
  5. Lung mitochondria adaptation to endurance training in rats
    Authors:
    Wiesława Jarmuszkiewicz, Karolina Dominiak, Łukasz Gałgański, Hanna Gałgańska, Anna Kicińska, Joanna Majerczak, Jerzy A. Żołądź
    Academic press:
    Free Radical Biology and Medicine (rok: 2020, tom: 161, strony: 163-174), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.011 - link to the publication

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