Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Molecular profile of exosomes present in bronchoalveolar lavage fluid as novel biomarker of immune dysfunction in non-small cell lung cancer

2017/27/B/NZ6/01990

Keywords:

exosomes lung cancer immunesuppression bronchoalveolar lavage fluid (BALF)

Descriptors:

  • NZ6_2:
  • NZ6_1:

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Lekarski

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Małgorzata Maria Czystowska-Kuźmicz 

Number of co-investigators in the project: 5

Call: OPUS 14 - announced on 2017-09-15

Amount awarded: 2 029 620 PLN

Project start date (Y-m-d): 2018-07-16

Project end date (Y-m-d): 2023-02-15

Project duration:: 55 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  • Book publications / chapters in book publications (1)
  1. EVs from BALF-Mediators of Inflammation and Potential Biomarkers in Lung Diseases
    Authors:
    Zareba L, Szymanski J, Homoncik Z, Czystowska-Kuzmicz M
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22 (7), strony: 3651), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22073651 - link to the publication
  2. Characterization of Extracellular Vesicles from Bronchoalveolar Lavage Fluid and Plasma of Patients with Lung Lesions Using Fluorescence Nanoparticle Tracking Analysis
    Authors:
    Dlugolecka M, Szymanski J, Zareba L, Homoncik Z, Domagala-Kulawik J, Polubiec-Kownacka M, Czystowska-Kuzmicz M
    Academic press:
    Cells (rok: 2021, tom: 10 (12), strony: 3473), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells10123473 - link to the publication
  3. The potential role of tumor-derived exosomes in diagnosis, prognosis, and response to therapy in cancer.
    Authors:
    Czystowska-Kuźmicz Małgorzata, Whiteside Theresa L.
    Academic press:
    Expert Opinion on Biological Therapy (rok: 2020, tom: 21, strony: 241-258), Wydawca: Taylor&Francis Online
    Status:
    Published
    DOI:
    10.1080/14712598.2020.1813276 - link to the publication
  4. Molecular cargo of small EVs from NSCLC patient BALF and plasma: unveiling their role in airway inflammation and immune regulation in a novel human 3D bronchial model
    Authors:
    Dlugolecka M, Szymanski J, Zareba L, Soroczynska K, Homoncik Z, Polubiec-Kownacka M, Frankiewicz E, Wierzbicka D, Thetchinamoorthy K, Domagala-Kulawik J, Czystowska-Kuzmicz M
    Academic press:
    Cell Communication and Signaling (rok: 2025, tom: 23, strony: 442), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1186/s12964-025-02423-5 - link to the publication
  1. Interplay between exosomes and autophagy: Are they partners in crime?. 2020
    Authors:
    Czystowska-Kuźmicz Małgorzata, Whiteside Theresa L.
    Book:
    Autophagy in Immune Response: Impact on Cancer Immunotherapy (rok: 2020, tom: 1, strony: 197 - 212), Wydawca: Academic Press
    Status:
    Published

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