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The role of the cortical somatostatin interneurons and their cholinergic modulation in brain plasticity induced by sensory deprivation.

2017/27/N/NZ4/02639

Keywords:

acetylcholine chemogenetics neuroplasticity sensory deprivation somatostatin interneurons

Descriptors:

  • NZ4_9: Systems neurobiology
  • NZ3_6: Cell neurobiology
  • NZ4_10: Neuroimaging and computational neuroscience

Panel:

NZ4 - Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology

Host institution :

Instytut Biologii Doświadczalnej im. M. Nenckiego Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Grzegorz Dobrzański 

Number of co-investigators in the project: 2

Call: PRELUDIUM 14 - announced on 2017-09-15

Amount awarded: 210 000 PLN

Project start date (Y-m-d): 2018-09-24

Project end date (Y-m-d): 2021-12-23

Project duration:: 39 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (2)
  1. Somatostatin and somatostatin containing interneurons - from plasticity to pathology.
    Authors:
    Monika Liguz-Lęcznar, Grzegorz Dobrzański, Małgorzata Kossut
    Academic press:
    Biomolecules (rok: 2022, tom: 12(2), strony: 312), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/biom12020312 - link to the publication
  2. Impact of somatostatin interneurons on interactions between barrels in plasticity induced by whisker deprivation
    Authors:
    Grzegorz Dobrzański, Renata Zakrzewska, Małgorzata Kossut, Monika Liguz-Lęcznar
    Academic press:
    Scientific Reports (rok: 2022, tom: 12, strony: 17992), Wydawca: Nature Portfolio
    Status:
    Published
    DOI:
    10.1038/s41598-022-22801-0 - link to the publication
  1. Somatostatin-expressing interneurons and sensory deprivation-induced plasticity in the barrel cortex.
    Authors:
    Grzegorz Dobrzański, Renata Zakrzewska, Małgorzata Kossut
    Conference:
    49th Meeting of the European Brain and Behaviour Society (rok: 2021, ), Wydawca: European Brain and Behaviour Society
    Data:
    konferencja 04-08.09.2021
    Status:
    Published
  2. Chemogenetic inhibition of somatostatin interneurons alters plasticity induced by sensory deprivation in the barrel cortex of mice.
    Authors:
    Grzegorz Dobrzański, Agnieszka Łukomska, Renata Zakrzewska, Małgorzata Kossut
    Conference:
    14th International Congress of the Polish Neuroscience Society (rok: 2019, ), Wydawca: Nencki Institute of Experimental Biology and Polish Neuroscience Society
    Data:
    konferencja 28-30.08.2019
    Status:
    Published

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