Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The study of neuroligin 3 mRNA interaction with fragile X mental retardation protein

2017/27/N/NZ1/01381

Keywords:

Neuroligin 3 FMRP REMSA single molecule FISH

Descriptors:

  • NZ1_1: Molecular biology
  • NZ1_2: Biochemistry

Panel:

NZ1 - Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution :

Uniwersytet Warszawski, Centrum Nowych Technologii Uniwersytetu Warszawskiego

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Joanna Chmielewska 

Number of co-investigators in the project: 2

Call: PRELUDIUM 14 - announced on 2017-09-15

Amount awarded: 208 400 PLN

Project start date (Y-m-d): 2018-08-03

Project end date (Y-m-d): 2021-08-02

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Komputer (4 000 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. Targeted therapy of cognitive deficits in fragile X syndrome
    Authors:
    A. Puścian, M. Winiarski, J. Borowska, S. Łęski, T. Górkiewicz, M. Chaturvedi, K. Nowicka, M. Wołyniak, J. J. Chmielewska, T. Nikolaev, K. Meyza, M. Dziembowska, L. Kaczmarek & E. Knapska
    Academic press:
    Molecular Psychiatry (rok: 2022, tom: Online ahead of print, strony: Online ahead of print), Wydawca: Springer Nature
    Status:
    Published
    DOI:
    10.1038/s41380-022-01527-5 - link to the publication
  2. PTPN4 germline variants result in aberrant neurodevelopment and growth.
    Authors:
    Joanna J. Chmielewska, Deepika Burkardt, Jorge Luis Granadillo, Rachel Slaugh, Shamile Morgan, Joshua Rotenberg, Boris Keren, Cyril Mignot, Luis Escobar, Peter Turnpenny, Melissa Zuteck, Laurie H. Seaver, Rafal Ploski, Magdalena Dziembowska, Anthony Wynshaw-Boris, Abidemi Adegbola
    Academic press:
    Human Genetics and Genomics Advances (rok: 2021, tom: 2, strony: 100033: 1-13), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.xhgg.2021.100033 - link to the publication
  1. Neuroligin 1, 2 and 3 regulation at the synapse: FMRP-dependent translation and activity-induced proteolytic cleavage
    Authors:
    Joanna Chmielewska, MSc, Centre of New Technologies, University of Warsaw, Warsaw, Poland
    Conference:
    I BioLAB Alumni Symposium (rok: 2019, ), Wydawca: I BioLAB Alumni Symposium Organizing Committee
    Data:
    konferencja 26-27.07.2019
    Status:
    Published