Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Evaluation of efficacy and safety of phage therapy in treatment of bacterial infection caused by Salmonella strains in poultry

2017/27/B/NZ9/00393

Keywords:

bacteriophages Salmonella phage therapy poultry infections

Descriptors:

  • NZ9_13: Other related subjects
  • NZ1_10: Microbiology
  • NZ9_8: Environmental microbiology

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Uniwersytet Gdański, Wydział Biologii

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Alicja Węgrzyn 

Number of co-investigators in the project: 7

Call: OPUS 14 - announced on 2017-09-15

Amount awarded: 2 019 500 PLN

Project start date (Y-m-d): 2018-07-20

Project end date (Y-m-d): 2023-07-19

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Ultrawirówka podłogowa Optima XPN-100 (490 000 PLN)

Information in the final report

  • Publication in academic press/journals (8)
  1. Highly different effects of phage therapy and antibiotic therapy on immunological responses of chickens infected with Salmonella enterica serovar Typhimurium
    Authors:
    Łukasz Grabowski, Grzegorz Węgrzyn, Alicja Węgrzyn, Magdalena Podlacha
    Academic press:
    Frontiers in Immunology (rok: 2022, tom: 13, strony: 956833), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fimmu.2022.956833 - link to the publication
  2. Phage Therapy vs. the Use of Antibiotics in the Treatment of Salmonella-Infected Chickens: Comparison of Effects on Hematological Parameters and Selected Biochemical Markers
    Authors:
    Łukasz Grabowski, Grzegorz Węgrzyn, Alicja Węgrzyn, Magdalena Podlacha
    Academic press:
    Antibiotics (rok: 2022, tom: 11, strony: 1787), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/antibiotics11121787 - link to the publication
  3. Bacteriophage DNA recognition by an animal immune system during phage therapy in the chicken model
    Authors:
    Lukasz Grabowski , Magdalena Podlacha ,Michal Grabski , Grzegorz Węgrzyn, Alicja Węgrzyn
    Academic press:
    Nature Communication (rok: 2023, tom: -, strony: -), Wydawca: Sringer-Nature
    Status:
    Submitted
    DOI:
    - - link to the publication
  4. Biological aspects of phage therapy versus antibiotics against Salmonella enterica serovar Typhimurium infection of chickens
    Authors:
    Katarzyna Kosznik-Kwaśnicka , Magdalena Podlacha, Łukasz Grabowski, Małgorzata Stasiłojć, Alicja Nowak-Zaleska, Karolina Ciemińska, Zuzanna, Cyske, Aleksandra Dydecka, Lidia Gaffke, Jagoda Mantej, Dorota Myślińska, Agnieszka Necel , Karolina Pierzynowska , Ewa Piotrowska, Edyta Radzanowska-Alenowicz, Estera Rintz , Krzysztof Sitko, Gracja Topka-Bielecka, Grzegorz Węgrzyn, Alicja Węgrzyn
    Academic press:
    Froniters in Cellular and Infection Microbiology (rok: 2022, tom: 12, strony: 941867), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fcimb.2022.941867 - link to the publication
  5. Efficacy and safety of phage therapy against Salmonella enterica serovars Typhimurium and Enteritidis estimated by using a battery of in vitro tests and the Galleria mellonella animal model
    Authors:
    Katarzyna Kosznik-Kwaśnicka , Małgorzata Stasiłojć , Łukasz Grabowski, Karolina Zdrojewska, Grzegorz Węgrzyn, Alicja Węgrzyn
    Academic press:
    Microbiological Research (rok: 2022, tom: 261, strony: 127052), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.micres.2022.127052 - link to the publication
  6. Interactions of bacteriophages with animal and human organisms-safety issues in the light of phage therapy
    Authors:
    Polacha M.; Grabowsk Ł.; Kosznik-Kwaśnicka K.; Zdrojewska K.; Stasiłojć M.; Wegrzyn G.; Węgrzyn A
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 8937), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22168937 - link to the publication
  7. Characteristic of a series of three bacteriophages infecting Salmonella enterica strains.
    Authors:
    Katarzyna Kosznik-Kwaśnicka, Karolina Ciemińska, Michał Grabski, Łukasz Grabowski, Marcin Górniak, Agata Jurczak-Kurek, Grzegorz Węgrzyn, Alicja Węgrzyn
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: 6152), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21176152 - link to the publication
  8. Bacteriophages vB_Sen-TO17 and vB_Sen-E22, Newly Isolated Viruses from Chicken Feces, Specific for Several Salmonella enterica Strains.
    Authors:
    Kosznik-Kwaśnicka K, Grabowski Ł, Grabski M, Kaszubski M, Górniak M, Jurczak-Kurek A, Węgrzyn G, Węgrzyn A.
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21, strony: 8821), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21228821. - link to the publication

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