Evaluation of efficacy and safety of phage therapy in treatment of bacterial infection caused by Salmonella strains in poultry

2017/27/B/NZ9/00393

Keywords

Descriptors

  • NZ9_13: Inne zagadnienia pokrewne
  • NZ1_10: Biologia drobnoustrojów
  • NZ9_8: Mikrobiologia środowiskowa

Panel

NZ9 – Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution

Uniwersytet Gdański, Wydział Biologii

Voivodeship: pomorskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Alicja Beata Węgrzyn

Number of co-investigators in the project: 7

Call

OPUS 14 – announced on 2017-09-15

Amount awarded
2 019 500 PLN
Project start date
2018-07-20
Project end date
2023-07-19
Project duration
60 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Ultrawirówka podłogowa Optima XPN-100. Cost: 490 000 PLN

Information in the final report

Publication in academic press/journals (7)

  1. Interactions of bacteriophages with animal and human organisms-safety issues in the light of phage therapy

    Authors:
    Polacha M.; Grabowsk Ł.; Kosznik-Kwaśnicka K.; Zdrojewska K.; Stasiłojć M.; Wegrzyn G.; Węgrzyn A
    Academic press:
    International Journal of Molecular Sciences (year: 2021, volume: 22, pages: 8937), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22168937 – link to the publication
  2. Bacteriophages vB_Sen-TO17 and vB_Sen-E22, Newly Isolated Viruses from Chicken Feces, Specific for Several Salmonella enterica Strains.

    Authors:
    Kosznik-Kwaśnicka K, Grabowski Ł, Grabski M, Kaszubski M, Górniak M, Jurczak-Kurek A, Węgrzyn G, Węgrzyn A.
    Academic press:
    International Journal of Molecular Sciences (year: 2020, volume: 21, pages: 8821), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21228821. – link to the publication
  3. Characteristic of a series of three bacteriophages infecting Salmonella enterica strains.

    Authors:
    Katarzyna Kosznik-Kwaśnicka, Karolina Ciemińska, Michał Grabski, Łukasz Grabowski, Marcin Górniak, Agata Jurczak-Kurek, Grzegorz Węgrzyn, Alicja Węgrzyn
    Academic press:
    International Journal of Molecular Sciences (year: 2020, volume: 21, pages: 6152), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms21176152 – link to the publication
  4. Efficacy and safety of phage therapy against Salmonella enterica serovars Typhimurium and Enteritidis estimated by using a battery of in vitro tests and the Galleria mellonella animal model

    Authors:
    Katarzyna Kosznik-Kwaśnicka , Małgorzata Stasiłojć , Łukasz Grabowski, Karolina Zdrojewska, Grzegorz Węgrzyn, Alicja Węgrzyn
    Academic press:
    Microbiological Research (year: 2022, volume: 261, pages: 127052), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.micres.2022.127052 – link to the publication
  5. Phage Therapy vs. the Use of Antibiotics in the Treatment of Salmonella-Infected Chickens: Comparison of Effects on Hematological Parameters and Selected Biochemical Markers

    Authors:
    Łukasz Grabowski, Grzegorz Węgrzyn, Alicja Węgrzyn, Magdalena Podlacha
    Academic press:
    Antibiotics (year: 2022, volume: 11, pages: 1787), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/antibiotics11121787 – link to the publication
  6. Highly different effects of phage therapy and antibiotic therapy on immunological responses of chickens infected with Salmonella enterica serovar Typhimurium

    Authors:
    Łukasz Grabowski, Grzegorz Węgrzyn, Alicja Węgrzyn, Magdalena Podlacha
    Academic press:
    Frontiers in Immunology (year: 2022, volume: 13, pages: 956833), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fimmu.2022.956833 – link to the publication
  7. Biological aspects of phage therapy versus antibiotics against Salmonella enterica serovar Typhimurium infection of chickens

    Authors:
    Katarzyna Kosznik-Kwaśnicka , Magdalena Podlacha, Łukasz Grabowski, Małgorzata Stasiłojć, Alicja Nowak-Zaleska, Karolina Ciemińska, Zuzanna, Cyske, Aleksandra Dydecka, Lidia Gaffke, Jagoda Mantej, Dorota Myślińska, Agnieszka Necel , Karolina Pierzynowska , Ewa Piotrowska, Edyta Radzanowska-Alenowicz, Estera Rintz , Krzysztof Sitko, Gracja Topka-Bielecka, Grzegorz Węgrzyn, Alicja Węgrzyn
    Academic press:
    Froniters in Cellular and Infection Microbiology (year: 2022, volume: 12, pages: 941867), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fcimb.2022.941867 – link to the publication

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Graphic design and implementation: Jakub Piotrowski