Projects funded by the NCN

Information on the principal investigator and host institution

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Role of microRNA-15 family, cell metabolism and hypoxia in proliferation of cardiomyocytes derived from human induced pluripotent stem cells.

2017/27/N/NZ3/00991

Keywords:

human induced pluripotent stem cells cardiomyocytes proliferation metabolism hypoxia micoRNA

Descriptors:

  • NZ3_8: Stem cell biology
  • NZ3_1: Cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Mateusz Jeż 

Number of co-investigators in the project: 2

Call: PRELUDIUM 14 - announced on 2017-09-15

Amount awarded: 140 000 PLN

Project start date (Y-m-d): 2018-08-03

Project end date (Y-m-d): 2021-08-02

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. Adaptation of cardiomyogenesis to the generation and maturation of cardiomyocytes from human pluripotent stem cells
    Authors:
    Alicja Martyniak, Mateusz Jeż, Józef Dulak | Jacek Stępniewski
    Academic press:
    IUBMB LIFE (rok: 2023, tom: 75, strony: 45533), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/iub.2685 - link to the publication
  2. Generation of miR-15a/16-1 cluster-deficient human induced pluripotent stem cell line (DMBi001-A-2) using CRISPR/Cas9 gene editing
    Authors:
    Jacek Stępniewski, Mateusz Jeż, Józef Dulak
    Academic press:
    Stem Cell Research (rok: 2023, tom: 68, strony: 45298), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.scr.2023.103046 - link to the publication
  3. Role of Heme-Oxygenase-1 in Biology of Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells
    Authors:
    Mateusz Jez, Alicja Martyniak, Kalina Andrysiak, Olga Mucha, Krzysztof Szade, Alan Kania, Lukasz Chrobok, Katarzyna Palus‐Chramiec, Anna M. Sanetra, Marian H. Lewandowski, Ewelina Pospiech, Jacek Stepniewski, Jozef Dulak
    Academic press:
    Cells (rok: 2021, tom: 10, strony: 45313), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells10030522 - link to the publication

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