Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Effects of embrionic signal on the conceptus and on global gene expression and DNA methylation in the endometrium in pigs in vivo

2017/27/B/NZ9/03014

Keywords:

pregnancy endometrium conceptus embryo signal estradiol

Descriptors:

  • NZ9_2: Animal production

Panel:

NZ9 - Fundamentals of applied life sciences and biotechnology: agricultural, forestry, horticulture, animal production and fishery, food and nutrition sciences, industrial biosciences, environmental biotechnology and remediation

Host institution :

Instytut Rozrodu Zwierząt i Badań Żywności Polskiej Akademii Nauk

woj. warmińsko-mazurskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Agnieszka Wacławik 

Number of co-investigators in the project: 4

Call: OPUS 14 - announced on 2017-09-15

Amount awarded: 999 628 PLN

Project start date (Y-m-d): 2018-08-31

Project end date (Y-m-d): 2022-08-30

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Zakup komputera o wysokiej mocy obliczeniowej wraz z oprogramowaniem do analiz bioinformatycznych. (9 500 PLN)

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (5)
  1. Estradiol-17β-Induced Changes in the Porcine Endometrial Transcriptome In Vivo
    Authors:
    Kaczynski Piotr, Bauersachs Stefan, Baryla Monika, Goryszewska Ewelina, Muszak Jolanta, Grzegorzewski Waldemar, Waclawik Agnieszka
    Academic press:
    International Journal of Molecular Sciences (rok: 2020, tom: 21(3), strony: E890), Wydawca: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/ijms21030890. - link to the publication
  2. Novel insights into conceptus-maternal signaling during pregnancy establishment in pigs
    Authors:
    Kaczyński, Piotr*; Goryszewska, Ewelina; Baryła, Monika; Wacławik, Agnieszka*
    Academic press:
    Molecular Reproduction and Development (rok: 2022, ), Wydawca: WILEY
    Status:
    Accepted for publication
    DOI:
    10.1002/mrd.23567 - link to the publication
  3. Synergistic action of estradiol and PGE2 on endometrial transcriptome in vivo resembles pregnancy effects better than estradiol alone
    Authors:
    Kaczyński Piotr, Bauersachs Stefan, Baryla Monika, Goryszewska Ewelina, Waclawik Agnieszka
    Academic press:
    Biology of Reproduction (rok: 2021, tom: 104(4), strony: 818-834), Wydawca: Oxford Academics
    Status:
    Published
    DOI:
    10.1093/biolre/ioaa230 - link to the publication
  4. Novel role for conceptus signals in mRNA expression regulation via DNA methylation in porcine endometrium during early pregnancy
    Authors:
    Kaczynski Piotr*, van der Weijden Vera, Goryszewska-Szczurek Ewelina, Baryla Monika, E. Ulbrich Susanne, Waclawik Agnieszka*
    Academic press:
    Biology of Reproduction (rok: 2022, ), Wydawca: Oxford Academics
    Status:
    Accepted for publication
    DOI:
    10.1093/biolre/ioac193 - link to the publication
  1. Embryo signals regulate expression and activity of DNA methyltransferases in vivo
    Authors:
    Waclawik Agnieszka, Kaczynski Piotr, Baryla Monika, Goryszewska-Szczurek Ewelina
    Conference:
    CellFit annual Meeting "The Three Dimensions of Cell Fit – Achievements, Challenges and Future Prospects" (rok: 2021, ), Wydawca: jointly published by the University of Thessaloniki, The Hebrew University, The University of Milan, The National Institute for Agriculture and Food Research and Technology and the COST Action CA16119.
    Data:
    konferencja 9-10.09.2021
    Status:
    Published
  2. Embryo signals regulate DNA methylation in the porcine endometrium in vivo
    Authors:
    Waclawik, Agnieszka; Kaczynski, Piotr; Goryszewska-Szczurek, Ewelina; Baryla, Monika
    Conference:
    Fertility Conference (rok: 2023, ), Wydawca: The Joint Fertility Conference Societies
    Data:
    konferencja 10-13.01.
    Status:
    Accepted for publication
  3. Embryonic signal regulates the porcine trophoblast cell functions
    Authors:
    Goryszewska-Szczurek, Ewelina; Baryla, Monika; Kaczynski, Piotr; Waclawik, Agnieszka
    Conference:
    Fertility (rok: 2023, ), Wydawca: The Joint Fertility Conference Societies
    Data:
    konferencja 10-13.01.
    Status:
    Accepted for publication
  4. Estradiol-17β and PGE2 regulate gene and protein expression of enzymes involved in DNA methylation in porcine endometrium in vivo
    Authors:
    Kaczynski, Piotr; Goryszewska-Szczurek, Ewelina; Baryla, Monika; Waclawik, Agnieszka
    Conference:
    Fertility (rok: 2023, ), Wydawca: The Joint Fertility Conference Societies
    Data:
    konferencja 10-13.01.
    Status:
    Accepted for publication
  5. Estradiol-induced changes in the porcine endometrial transcriptome in vivo
    Authors:
    Waclawik Agnieszka, Kaczynski Piotr, Bauersachcs Stefan, Baryla Monika, Goryszewska Ewelina
    Conference:
    3rd CellFit Annual Meeting (rok: 2019, ), Wydawca: -
    Data:
    konferencja 43748
    Status:
    Published

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