Projects funded by the NCN

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Information of the project and the call

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Development of a hybrid model bioreactor to study the effect of variable glucose concentration on metabolism and oxidative stress in endothelial cells

2017/27/B/ST7/00269

Keywords:

hybrid model capillary bioreactor diabetes endothelial cells HUVEC smooth muscle cells

Descriptors:

  • ST7_11:

Panel:

ST7 - Systems and communication engineering: electronics, communication, optoelectronics

Host institution :

Instytut Biocybernetyki i Inżynierii Biomedycznej im. Macieja Nałęcza Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Piotr Ładyżyński 

Number of co-investigators in the project: 7

Call: OPUS 14 - announced on 2017-09-15

Amount awarded: 975 700 PLN

Project start date (Y-m-d): 2018-07-31

Project end date (Y-m-d): 2023-07-30

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (4)
  1. Effect of glucose concentration and culture substrate on HUVEC viability in in vitro cultures: a literature review and own results
    Authors:
    Anna Ciechanowska, Ilona Góra, Stanisława Sabalińska, Piotr Foltyński, Piotr Ładyżyński
    Academic press:
    Biocybernetics and Biomedical Engineering (rok: 2021, tom: Vol. 41, No. 4, strony: 1390-1405), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.bbe.2021.04.010 - link to the publication
  2. The effect of high and variable glucose on the viability of endothelial cells co-cultured with smooth muscle cells
    Authors:
    Anna Ciechanowska , Ilona M. Góra , Stanisława Sabalińska, Piotr Ładyżyński
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: artykuł nr 6704, str. 1-18), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23126704 - link to the publication
  3. NLRP3 inflammasome at the interface of inflammation, endothelial dysfunction, and type 2 diabetes
    Authors:
    Ilona M. Góra, Anna Ciechanowska, Piotr Ładyżyński
    Academic press:
    Cells (rok: 2021, tom: 10, strony: artykuł nr 314, str. 1-28), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/cells10020314 - link to the publication
  4. Modeling blood vessel dynamics: Effects of glucose variations on HUVECs in a hollow fiber bioreactor under laminar shear stress
    Authors:
    Piotr Ładyżyński, Anna Ciechanowska, Stanisława Sabalińska, Piotr Foltyński, Agnieszka Wencel, Cezary Wojciechowski, Krzysztof Pluta, Andrzej Chwojnowski
    Academic press:
    Biocybernetics and Biomedical Engineering (rok: 2024, tom: Vol. 44, No. 3, strony: 543-559), Wydawca: ELSEVIER
    Status:
    Published
    DOI:
    10.1016/j.bbe.2024.08.004 - link to the publication

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