Development of a hybrid model bioreactor to study the effect of variable glucose

Development of a hybrid model bioreactor to study the effect of variable glucose concentration on metabolism and oxidative stress in endothelial cells

2017/27/B/ST7/00269

Keywords

Descriptors

ST7_11: Inżynieria biomedyczna

Panel

ST7 – Systems and communication engineering: electronics, communication, optoelectronics

Host institution

Instytut Biocybernetyki i Inżynierii Biomedycznej im. Macieja Nałęcza PAN

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Piotr Ładyżyński

Number of co-investigators in the project: 7

Call

OPUS 14 – announced on 2017-09-15

Amount awarded: 975 700 PLN
Project start date: 2018-07-31
Project end date: 2023-07-30
Project duration: 60 months (the same as in the proposal)
Project status: Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (4)

Effect of glucose concentration and culture substrate on HUVEC viability in in vitro cultures: a literature review and own results

Authors:
Anna Ciechanowska, Ilona Góra, Stanisława Sabalińska, Piotr Foltyński, Piotr Ładyżyński

Academic press:
Biocybernetics and Biomedical Engineering (year: 2021, volume: Vol. 41, No. 4, pages: 1390-1405), Publisher: ELSEVIER

Status:
Published

DOI:
10.1016/j.bbe.2021.04.010 – link to the publication
The effect of high and variable glucose on the viability of endothelial cells co-cultured with smooth muscle cells

Authors:
Anna Ciechanowska , Ilona M. Góra , Stanisława Sabalińska, Piotr Ładyżyński

Academic press:
International Journal of Molecular Sciences (year: 2022, volume: 23, pages: artykuł nr 6704, str. 1-18), Publisher: MDPI

Status:
Published

DOI:
10.3390/ijms23126704 – link to the publication
NLRP3 inflammasome at the interface of inflammation, endothelial dysfunction, and type 2 diabetes

Authors:
Ilona M. Góra, Anna Ciechanowska, Piotr Ładyżyński

Academic press:
Cells (year: 2021, volume: 10, pages: artykuł nr 314, str. 1-28), Publisher: MDPI

Status:
Published

DOI:
10.3390/cells10020314 – link to the publication
Modeling blood vessel dynamics: Effects of glucose variations on HUVECs in a hollow fiber bioreactor under laminar shear stress

Authors:
Piotr Ładyżyński, Anna Ciechanowska, Stanisława Sabalińska, Piotr Foltyński, Agnieszka Wencel, Cezary Wojciechowski, Krzysztof Pluta, Andrzej Chwojnowski

Academic press:
Biocybernetics and Biomedical Engineering (year: 2024, volume: Vol. 44, No. 3, pages: 543-559), Publisher: ELSEVIER

Status:
Published

DOI:
10.1016/j.bbe.2024.08.004 – link to the publication

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