Impact of indoxyl sulfate on disturbances of bone homeostasis
2017/27/N/NZ4/00033
Keywords
Descriptors
- NZ4_4: Patofizjologia ogólna
Panel
NZ4 – Biology of tissues, organs and organisms: morphology and functions of animal's and human's systems, organs and organisms, experimental medicine, basics of neurology
Host institution
Uniwersytet Medyczny w Białymstoku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej
Voivodeship: podlaskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 3
Call
PRELUDIUM 14 – announced on 2017-09-15
- Amount awarded
- 210 000 PLN
- Project start date
- 2018-08-10
- Project end date
- 2022-08-09
- Project duration
- 48 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Information in the final report
Publication in academic press/journals (1)
-
Dose‑dependent exposure to indoxyl sulfate alters AHR signaling, sirtuins gene expression, oxidative DNA damage, and bone mineral status in rats
- Authors:
- Malgorzata Karbowska, Krystyna Pawlak, Beata Sieklucka, Tomasz Domaniewski, Urszula Lebkowska, Radoslaw Zawadzki & Dariusz Pawlak
- Academic press:
- Scientific Reports (year: 2024, volume: 14, 2583 (2024), pages: 46035), Publisher: Springer Nature
- Status:
- Published
- DOI:
- 10.1038/s41598-024-53164-3 – link to the publication
Articles in post-conference publications (2)
-
The effect of chronic exposure to indoxyl sulfate on geometric, densitometric and morphometric parameters of bones in animal model
- Authors:
- Karbowska M., Sieklucka B., Kaminski T., Mor A., Lipowicz P., Zawadzki R., Pawlak K., Pawlak D.
- Conference:
- ISN World Congress of Nephrology (WCN), Melbourne, Australia, (year: 2019, pages: S51), Publisher: Official Journal of the International Society of Nephrology, Elsevier
- Date:
- conference 12-15.04.19.
- Status:
- Published
-
CHRONIC EXPOSURE TO INDOXYL SULFATE CHANGES BONE PROPERTIES AND EXPRESSION OF SIRT2, SIRT3, AND SIRT7 GENES
- Authors:
- Malgorzata Karbowska, Beata Sieklucka, Tomasz Domaniewski, Malgorzata Galazyn-Sidorczuk, Krystyna Pawlak, Dariusz Pawlak
- Conference:
- 58th ERA EDTA Virtual Congress 2021 in Berlin (year: 2021, pages: i338), Publisher: Oxford University Press, Nephrology Dialysis Transplantation, Volume 36, Issue Supplement_1, May 2021, gfab086.002
- Date:
- conference 05.-08.06.2021.
- Status:
- Published