Immunogenic properties of hepatitis C virus NS3 protein epitopes fused to hepatitis B small surface antigen

2017/27/B/NZ6/01403

Keywords

Descriptors

  • NZ6_5: Wirusologia
  • NZ1_1: Biologia molekularna

Panel

NZ6 – Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

Voivodeship: pomorskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Katarzyna Monika Grzyb

Number of co-investigators in the project: 3

Call

OPUS 14 – announced on 2017-09-15

Amount awarded
1 410 400 PLN
Project start date
2018-10-02
Project end date
2022-10-01
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (2)

  1. Specific antibodies induced by immunization with hepatitis B virus-like particles carrying hepatitis C virus envelope glycoprotein 2 epitopes show differential neutralization efficiency

    Authors:
    Anna Czarnota, Anna Offersgaard, Anne Finne Pihl, Jannick Prentoe, Jens Bukh, Judith Margarete Gottwein, Krystyna Bieńkowska-Szewczyk and Katarzyna Grzyb*
    Academic press:
    Vaccines (year: 2020, volume: 8, pages: 46041), Publisher: mdpi
    Status:
    Published
    DOI:
    10.3390/vaccines8020294 – link to the publication
  2. The effect of glycan shift on antibodies against HCV E2 412-425 epitope elicited by chimeric sHBsAg-based virus-like particles

    Authors:
    Anna Czarnota, Anna Offersgaard, Ania Owsianka, Garazi Peña Alzua, Jens Bukh, Judith Margarete Gottwein, Arvind H. Patel, Krystyna Bieńkowska-Szewczyk, Katarzyna Grzyb
    Academic press:
    Microbiology Spectrum (year: 2023, volume: 11, pages: 46039), Publisher: ASM Journals
    Status:
    Published
    DOI:
    10.1128/spectrum.02546-22 – link to the publication

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