Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Immunogenic properties of hepatitis C virus NS3 protein epitopes fused to hepatitis B small surface antigen

2017/27/B/NZ6/01403

Keywords:

Hepatitis C virus (HCV) Hepatitis B small surface antigen (sHBsAg) vaccine

Descriptors:

  • NZ6_5:
  • NZ1_1:

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Gdański, Międzyuczelniany Wydział Biotechnologii Uniwersytetu Gdańskiego i Gdańskiego Uniwersytetu Medycznego

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Katarzyna Monika Grzyb 

Number of co-investigators in the project: 3

Call: OPUS 14 - announced on 2017-09-15

Amount awarded: 1 410 400 PLN

Project start date (Y-m-d): 2018-10-02

Project end date (Y-m-d): 2022-10-01

Project duration:: 48 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (3)
  1. The effect of glycan shift on antibodies against HCV E2 412-425 epitope elicited by chimeric sHBsAg-based virus-like particles
    Authors:
    Anna Czarnota, Anna Offersgaard, Ania Owsianka, Garazi Peña Alzua, Jens Bukh, Judith Margarete Gottwein, Arvind H. Patel, Krystyna Bieńkowska-Szewczyk, Katarzyna Grzyb
    Academic press:
    Microbiology Spectrum (rok: 2023, tom: 11, strony: 45674), Wydawca: ASM Journals
    Status:
    Published
    DOI:
    10.1128/spectrum.02546-22 - link to the publication
  2. Specific antibodies induced by immunization with hepatitis B virus-like particles carrying hepatitis C virus envelope glycoprotein 2 epitopes show differential neutralization efficiency
    Authors:
    Anna Czarnota, Anna Offersgaard, Anne Finne Pihl, Jannick Prentoe, Jens Bukh, Judith Margarete Gottwein, Krystyna Bieńkowska-Szewczyk and Katarzyna Grzyb*
    Academic press:
    Vaccines (rok: 2020, tom: 8, strony: 45676), Wydawca: mdpi
    Status:
    Published
    DOI:
    10.3390/vaccines8020294 - link to the publication
  3. The effect of glycan shift on antibodies against HCV E2 412-425 epitope elicited by chimeric sHBsAg-based virus-like particles
    Authors:
    Anna Czarnota, Anna Offersgaard, Ania Owsianka, Garazi Peña Alzua, Jens Bukh, Judith Margarete Gottwein, Arvind H. Patel, Krystyna Bieńkowska-Szewczyk, Katarzyna Grzyb
    Academic press:
    Microbiology Spectrum (rok: 2023, tom: 11, strony: 45674), Wydawca: ASM Journals
    Status:
    Published
    DOI:
    10.1128/spectrum.02546-22 - link to the publication

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