Assesment the role of cannabidiol in the regulation of fatty acid transport proteins (FAT/CD36, FABPpm and FATP1,4,6) expression in cardiac muscle of rats with high fat diet induced insulin resistance.
2017/26/D/NZ3/01119
Keywords
Descriptors
- NZ3_2: Fizjologia komórki
- NZ3_7: Przekaźnictwo sygnału
Panel
NZ3 – Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology
Host institution
Uniwersytet Medyczny w Białymstoku, Wydział Lekarski z Oddziałem Stomatologii i Oddziałem Nauczania w Języku Angielskim
Voivodeship: podlaskie
Principal investigator (from the host institution)
Number of co-investigators in the project: 6
Call
SONATA 13 – announced on 2017-06-14
- Amount awarded
- 771 860 PLN
- Project start date
- 2018-04-13
- Project end date
- 2021-04-12
- Project duration
- 36 months (the same as in the proposal)
- Project status
- Project settled
Project description
Download the project description in a pdf file
Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.
Equipment purchased [PL]
- Aparat do perfuzji serca szczura w systemie Langendorffa wraz z oprogramowaniem ISOHEART i komputerem firmy Hugo Sachs Electronic. Cost: 186 660 PLN
Information in the final report
Publication in academic press/journals (5)
-
Attenuation of Oxidative Stress and Inflammatory Response by Chronic Cannabidiol Administration Is Associated with Improved n-6/n-3 PUFA Ratio in the White and Red Skeletal Muscle in a Rat Model of High-Fat Diet-Induced Obesity
- Authors:
- Patrycja Bielawiec, Ewa Harasim-Symbor, Klaudia Sztolsztene, Karolina Konstantynowicz-Nowicka, Adrian Chabowski.
- Academic press:
- Nutrients (year: 2021, volume: 13(5), pages: 1603), Publisher: Multidisciplinary Digital Publishing Institute
- Status:
- Published
- DOI:
- 10.3390/nu13051603 – link to the publication
-
Chronic Cannabidiol Administration Attenuates Skeletal Muscle De Novo Ceramide Synthesis Pathway and Related Metabolic Effects in a Rat Model of High-Fat Diet-Induced Obesity.
- Authors:
- Bielawiec Patrycja, Harasim-Symbor Ewa, Konstantynowicz-Nowicka Karolina, Sztolsztener Klaudia, Chabowski Adrian.
- Academic press:
- Biomolecules (year: 2020, volume: 10(9), pages: 1241), Publisher: Multidisciplinary Digital Publishing Institute
- Status:
- Published
- DOI:
- 10.3390/biom10091241 – link to the publication
-
Phytocannabinoids: Useful Drugs for the Treatment of Obesity? Special Focus on Cannabidiol
- Authors:
- Patrycja Bielawiec, Ewa Harasim-Symbor and Adrian Chabowski
- Academic press:
- Frontiers in Endocrinology (year: 2020, volume: 11, pages: 11 pp), Publisher: Frontiers
- Status:
- Published
- DOI:
- 10.3389/fendo.2020.00114 – link to the publication
-
Cannabidiol downregulates myocardial de novo ceramide synthesis pathway in a rat model of high-fat diet-induced obesity.
- Authors:
- Charytoniuk Tomasz, Sztolsztener Klaudia, Bielawiec Patrycja, Chabowski Adrian, Konstantynowicz-Nowicka Karolina, Harasim-Symbor Ewa
- Academic press:
- International Journal of Molecular Sciences (year: 2022, volume: 23(4), pages: 17pp), Publisher: MDPI
- Status:
- Published
- DOI:
- 10.3390/ijms23042232 – link to the publication
-
Cannabidiol - a phytocannabinoid that widely affects sphingolipid metabolism under conditions of brain insulin resistance.
- Authors:
- Charytoniuk Tomasz, Sztolsztener Klaudia, Harasim-Symbor Ewa, Berk Klaudia, Chabowski Adrian, Konstantynowicz-Nowicka Karolina
- Academic press:
- Biomedicine & Pharmacotherapy (year: 2021, volume: 142, pages: 12pp), Publisher: Elsevier
- Status:
- Published
- DOI:
- 10.1016/j.biopha.2021.112057 – link to the publication
Articles in post-conference publications (1)
-
Cannabidiol regulates myocardial lipid metabolism in a rat model of obesity.
- Authors:
- Harasim-Symbor Ewa, Bielawiec Patrycja, Konstantynowicz-Nowicka Karolina
- Conference:
- 31th Annual Symposium of the International Cannabinoid Research Society, Jerusalem, Israel (year: 2021, pages: P3-14), Publisher: International Cannabinoid Research Society
- Date:
- conference June 21-24
- Status:
- Published