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Investigations of the anticancer properties of the titanium carbides and nitrides - MXenes phases

2017/26/E/ST8/01073

Keywords

Descriptors

  • ST8_8: Inżynieria materiałowa (biomateriały, metale, ceramika, polimery, kompozyty)
  • ST3_12: Nanofizyka: nanoelekronika, nanofotonika, nanomagnetyzm
  • ST5_10: Nanomateriały: nanocząstki, nanorurki

Panel

ST8 – Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution

Politechnika Warszawska, Wydział Inżynierii Materiałowej

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Agnieszka Maria Jastrzębska

Number of co-investigators in the project: 10

Call

SONATA BIS 7 – announced on 2017-06-14

Amount awarded
1 952 200 PLN
Project start date
2018-04-26
Project end date
2022-10-25
Project duration
54 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Liofilizator laboratoryjny. Cost: 60 000 PLN
  2. Moduł analizy optycznej z opcją sortowania komórek do cytometru przepływowego. Cost: 98 000 PLN
  3. Moduł do liofilizacji w rozpuszczalnikach niewodnych z zamrażarką.
  4. Spektrometr FTIR. Cost: 120 000 PLN
  5. reaktor do syntezy solwotermalnej.
  6. spektrofotometr UV-VIS.
  7. waga laboratoryjna.
  8. wieloprocesorowa stacja robocza. Cost: 25 000 PLN

Information in the final report

Publication in academic press/journals (15)

  1. Colloidal Properties and Stability of 2D Ti3C2 and Ti2C MXenes in Water

    Authors:
    A. Rozmysłowska, T. Wojciechowski, W. Ziemkowska, L. Chlubny, A. Olszyna, S. Poźniak, K. Tomkiewicz, A. M. Jastrzębska
    Academic press:
    International Journal of Electrochemical Science (year: 2018, volume: 13, pages: 10837 – 10847), Publisher: ESG
    Status:
    Published
    DOI:
    10.20964/2018.11.56 – link to the publication

  2. On the rapid in situ oxidation of two-dimensional V2CTz MXene in culture cell media and their cytotoxicity

    Authors:
    A. M. Jastrzębska, B. Scheibe, A. Szuplewska, A. Rozmysłowska-Wojciechowska, M. Chudy, C. Aparicio, M. Scheibe, I. Janica, A. Ciesielski, M. Otyepka, M. W. Barsoum
    Academic press:
    Materials Science and Engineering: C (year: 2021, volume: 119, pages: 111431), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2020.111431 – link to the publication

  3. 2D Ti2C (MXene) as a novel, highly efficient agent for photothermal therapy

    Authors:
    A. Szuplewska, D. Kalinowska, A. Dybko, A. M. Jastrzębska, T. Wojciechowski, A. Rozmysłowska, M. Chudy, I. Grabowska-Jadach, W. Ziemkowska, Z. Brzózka, A. Olszyna
    Academic press:
    Materials Science and Engineering C (year: 2019, volume: 98, pages: 874-886), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2019.01.021 – link to the publication

  4. Smart and Sustainable Nanotechnological Solutions in a Battle Against COVID-19 and Beyond

    Authors:
    A.M. Jastrzębska, A.S. Vasilchenko
    Academic press:
    ACS Sustainable Chemistry & Engineering (year: 2021, volume: 9, 2, pages: 601-622), Publisher: ACS
    Status:
    Published
    DOI:
    10.1021/acssuschemeng.0c065 – link to the publication

  5. A Review on Development of Ceramic-Graphene Based Nanohybrid Composite Systems in Biological Applications

    Authors:
    M. Jakubczak, A.M. Jastrzębska
    Academic press:
    Frontiers in Chemistry (year: 2021, volume: 9, pages: 685014), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fchem.2021.685014 – link to the publication

  6. The 10th anniversary of MXenes: Challenges and Prospects for their Surface Modification Toward Future Biotechnological Application

    Authors:
    A. Szuplewska, D. Kulpińska, M. Jakubczak, A. Dybko, M. Chudy, A. Olszyna, Z. Brzózka, A.M. Jastrzębska
    Academic press:
    Advanced Drug Delivery Reviews (year: 2021, volume: 182, pages: 114099), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.addr.2021.114099 – link to the publication

  7. New Findings of MXenes: Preparation, Properties and Application in Biotechnology and Catalysis

    Authors:
    A. M. Jastrzębska, J. Woźniak
    Academic press:
    Materials (year: 2021, volume: 14 (4), pages: 892), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14040892 – link to the publication

  8. Juggling surface charges of 2D Niobium Carbide MXenes for a reactive oxygen species scavenging and effective targeting of the malignant melanoma cell cycle into programmed cell death

    Authors:
    A. Jastrzębska, A. Szuplewska, A. Rozmysłowska-Wojciechowska, J. Mitrzak, T. Wojciechowski, M. Chudy, D. Moszczyńska, A. Wójcik, K. Prenger, M. Naguib
    Academic press:
    ACS Sustainable Chemistry & Engineering (year: 2020, volume: 8, pages: 7942-7951), Publisher: ACS
    Status:
    Published
    DOI:
    10.1021/acssuschemeng.0c01609 – link to the publication

  9. On tuning the cytotoxicity of Ti3C2 (MXene) flakes to cancerous and benign cells by post-delamination surface modifications

    Authors:
    A. M. Jastrzębska, A. Szuplewska, A. Rozmysłowska-Wojciechowska, M. Chudy, A. Olszyna, M. Birowska, M. Popielski, J. A. Majewski, B. Scheibe, V. Natu, M. W. Barsoum
    Academic press:
    2D Materials (year: 2020, volume: 7, 2, pages: 46034), Publisher: IOP Publishing Ltd
    Status:
    Published
    DOI:
    10.1088/2053-1583/ab6a60 – link to the publication

  10. Engineering of 2D Ti3C2 MXene Surface Charge and its Influence on Biological Properties

    Authors:
    A. Rozmysłowska-Wojciechowska, J. Mitrzak, A. Szuplewska, M. Chudy, J. Woźniak, M. Petrus, T. Wojciechowski, A.S. Vasilchenko, A. M. Jastrzębska
    Academic press:
    Materials (year: 2020, volume: 13, 10, pages: 2347), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ma13102347 – link to the publication

  11. Surface-Related Features Responsible for Cytotoxic Behavior of MXenes Layered Materials Predicted with Machine Learning Approach

    Authors:
    M. E. Marchwiany, M. Birowska, M. Popielski, J.A. Majewski, A. M. Jastrzębska
    Academic press:
    Materials (year: 2020, volume: 13, 14, pages: 3083), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ma13143083 – link to the publication

  12. Multilayered stable 2D nano-sheets of Ti2NTx MXene: synthesis, characterization, and anticancer activity

    Authors:
    A. Szuplewska, A. Rozmysłowska‑Wojciechowska, S. Poźniak, T. Wojciechowski, M. Birowska, M. Popielski, M. Chudy, W. Ziemkowska, L. Chlubny, D. Moszczyńska, A. Olszyna, J. A. Majewski, A. M. Jastrzębska
    Academic press:
    Journal of Nanobiotechnology (year: 2019, volume: 17, 114, pages: 46036), Publisher: BioMed Central Ltd
    Status:
    Published
    DOI:
    10.1186/s12951-019-0545-4 – link to the publication

  13. Controlling the Porosity and Biocidal Properties of the Chitosan-Hyaluronate Matrix Hydrogel Nanocomposites by the Addition of 2D Ti3C2Tx MXene

    Authors:
    A. Rozmysłowska-Wojciechowska, E. Karwowska, M. Gloc, J. Woźniak, M. Petrus, T. Wojciechowski, A. M. Jastrzębska
    Academic press:
    Materials (year: 2020, volume: 13, 20, pages: 4587), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ma13204587 – link to the publication

  14. Filtration Materials Modified with 2D Nanocomposites – A New Perspective for Point-of-Use Water Treatment

    Authors:
    M. Jakubczak, E. Karwowska, A. Rozmysłowska-Wojciechowska, M. Petrus, J. Woźniak, J. Mitrzak, A. M. Jastrzębska
    Academic press:
    Materials (year: 2021, volume: 14, 1, pages: 182), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14010182 – link to the publication

  15. Future Applications of MXenes in Biotechnology, Nanomedicine, and Sensors

    Authors:
    A. Szuplewska, D. Kulpinska, A. Dybko, M. Chudy, A. M. Jastrzębska, A. Olszyna, Z. Brzózka
    Academic press:
    Trends in Biotechnology (year: 2020, volume: 38, 3, pages: 264-279), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.tibtech.2019.09.001 – link to the publication

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Graphic design and implementation: Jakub Piotrowski