Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Investigations of the anticancer properties of the titanium carbides and nitrides - MXenes phases

2017/26/E/ST8/01073

Keywords:

2D crystals flakes early transition metal carbides and nitrides MAX phases MXene manufacturing expanding modification bioactivity in vitro anticancer properties mechanisms

Descriptors:

  • ST8_8: Mechanics of solids
  • ST3_12: Molecular electronics
  • ST5_10: Functional materials/nanomaterials, nanoparticles

Panel:

ST8 - Production and processes engineering: modelling, product design, process design and control, construction methods and engineering, power units and systems

Host institution :

Politechnika Warszawska, Wydział Inżynierii Materiałowej

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Agnieszka Jastrzębska 

Number of co-investigators in the project: 10

Call: SONATA BIS 7 - announced on 2017-06-14

Amount awarded: 1 952 200 PLN

Project start date (Y-m-d): 2018-04-26

Project end date (Y-m-d): 2022-10-25

Project duration:: 54 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Liofilizator laboratoryjny (60 000 PLN)
  2. Moduł do liofilizacji w rozpuszczalnikach niewodnych z zamrażarką.
  3. wieloprocesorowa stacja robocza (25 000 PLN)
  4. Moduł analizy optycznej z opcją sortowania komórek do cytometru przepływowego (98 000 PLN)
  5. Spektrometr FTIR (120 000 PLN)
  6. reaktor do syntezy solwotermalnej.
  7. waga laboratoryjna.
  8. spektrofotometr UV-VIS.

Information in the final report

  • Publication in academic press/journals (15)
  1. 2D Ti2C (MXene) as a novel, highly efficient agent for photothermal therapy
    Authors:
    A. Szuplewska, D. Kalinowska, A. Dybko, A. M. Jastrzębska, T. Wojciechowski, A. Rozmysłowska, M. Chudy, I. Grabowska-Jadach, W. Ziemkowska, Z. Brzózka, A. Olszyna
    Academic press:
    Materials Science and Engineering C (rok: 2019, tom: 98, strony: 874-886), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2019.01.021 - link to the publication
  2. Engineering of 2D Ti3C2 MXene Surface Charge and its Influence on Biological Properties
    Authors:
    A. Rozmysłowska-Wojciechowska, J. Mitrzak, A. Szuplewska, M. Chudy, J. Woźniak, M. Petrus, T. Wojciechowski, A.S. Vasilchenko, A. M. Jastrzębska
    Academic press:
    Materials (rok: 2020, tom: 13, 10, strony: 2347), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma13102347 - link to the publication
  3. Controlling the Porosity and Biocidal Properties of the Chitosan-Hyaluronate Matrix Hydrogel Nanocomposites by the Addition of 2D Ti3C2Tx MXene
    Authors:
    A. Rozmysłowska-Wojciechowska, E. Karwowska, M. Gloc, J. Woźniak, M. Petrus, T. Wojciechowski, A. M. Jastrzębska
    Academic press:
    Materials (rok: 2020, tom: 13, 20, strony: 4587), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma13204587 - link to the publication
  4. Filtration Materials Modified with 2D Nanocomposites – A New Perspective for Point-of-Use Water Treatment
    Authors:
    M. Jakubczak, E. Karwowska, A. Rozmysłowska-Wojciechowska, M. Petrus, J. Woźniak, J. Mitrzak, A. M. Jastrzębska
    Academic press:
    Materials (rok: 2021, tom: 14, 1, strony: 182), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14010182 - link to the publication
  5. Juggling surface charges of 2D Niobium Carbide MXenes for a reactive oxygen species scavenging and effective targeting of the malignant melanoma cell cycle into programmed cell death
    Authors:
    A. Jastrzębska, A. Szuplewska, A. Rozmysłowska-Wojciechowska, J. Mitrzak, T. Wojciechowski, M. Chudy, D. Moszczyńska, A. Wójcik, K. Prenger, M. Naguib
    Academic press:
    ACS Sustainable Chemistry & Engineering (rok: 2020, tom: 8, strony: 7942-7951), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acssuschemeng.0c01609 - link to the publication
  6. Surface-Related Features Responsible for Cytotoxic Behavior of MXenes Layered Materials Predicted with Machine Learning Approach
    Authors:
    M. E. Marchwiany, M. Birowska, M. Popielski, J.A. Majewski, A. M. Jastrzębska
    Academic press:
    Materials (rok: 2020, tom: 13, 14, strony: 3083), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma13143083 - link to the publication
  7. Future Applications of MXenes in Biotechnology, Nanomedicine, and Sensors
    Authors:
    A. Szuplewska, D. Kulpinska, A. Dybko, M. Chudy, A. M. Jastrzębska, A. Olszyna, Z. Brzózka
    Academic press:
    Trends in Biotechnology (rok: 2020, tom: 38, 3, strony: 264-279), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.tibtech.2019.09.001 - link to the publication
  8. On tuning the cytotoxicity of Ti3C2 (MXene) flakes to cancerous and benign cells by post-delamination surface modifications
    Authors:
    A. M. Jastrzębska, A. Szuplewska, A. Rozmysłowska-Wojciechowska, M. Chudy, A. Olszyna, M. Birowska, M. Popielski, J. A. Majewski, B. Scheibe, V. Natu, M. W. Barsoum
    Academic press:
    2D Materials (rok: 2020, tom: 7, 2, strony: 45303), Wydawca: IOP Publishing Ltd
    Status:
    Published
    DOI:
    10.1088/2053-1583/ab6a60 - link to the publication
  9. Smart and Sustainable Nanotechnological Solutions in a Battle Against COVID-19 and Beyond
    Authors:
    A.M. Jastrzębska, A.S. Vasilchenko
    Academic press:
    ACS Sustainable Chemistry & Engineering (rok: 2021, tom: 9, 2, strony: 601-622), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acssuschemeng.0c065 - link to the publication
  10. A Review on Development of Ceramic-Graphene Based Nanohybrid Composite Systems in Biological Applications
    Authors:
    M. Jakubczak, A.M. Jastrzębska
    Academic press:
    Frontiers in Chemistry (rok: 2021, tom: 9, strony: 685014), Wydawca: Frontiers
    Status:
    Published
    DOI:
    10.3389/fchem.2021.685014 - link to the publication
  11. Colloidal Properties and Stability of 2D Ti3C2 and Ti2C MXenes in Water
    Authors:
    A. Rozmysłowska, T. Wojciechowski, W. Ziemkowska, L. Chlubny, A. Olszyna, S. Poźniak, K. Tomkiewicz, A. M. Jastrzębska
    Academic press:
    International Journal of Electrochemical Science (rok: 2018, tom: 13, strony: 10837 – 10847), Wydawca: ESG
    Status:
    Published
    DOI:
    10.20964/2018.11.56 - link to the publication
  12. Multilayered stable 2D nano-sheets of Ti2NTx MXene: synthesis, characterization, and anticancer activity
    Authors:
    A. Szuplewska, A. Rozmysłowska‑Wojciechowska, S. Poźniak, T. Wojciechowski, M. Birowska, M. Popielski, M. Chudy, W. Ziemkowska, L. Chlubny, D. Moszczyńska, A. Olszyna, J. A. Majewski, A. M. Jastrzębska
    Academic press:
    Journal of Nanobiotechnology (rok: 2019, tom: 17, 114, strony: 45305), Wydawca: BioMed Central Ltd
    Status:
    Published
    DOI:
    10.1186/s12951-019-0545-4 - link to the publication
  13. New Findings of MXenes: Preparation, Properties and Application in Biotechnology and Catalysis
    Authors:
    A. M. Jastrzębska, J. Woźniak
    Academic press:
    Materials (rok: 2021, tom: 14 (4), strony: 892), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma14040892 - link to the publication
  14. On the rapid in situ oxidation of two-dimensional V2CTz MXene in culture cell media and their cytotoxicity
    Authors:
    A. M. Jastrzębska, B. Scheibe, A. Szuplewska, A. Rozmysłowska-Wojciechowska, M. Chudy, C. Aparicio, M. Scheibe, I. Janica, A. Ciesielski, M. Otyepka, M. W. Barsoum
    Academic press:
    Materials Science and Engineering: C (rok: 2021, tom: 119, strony: 111431), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.msec.2020.111431 - link to the publication
  15. The 10th anniversary of MXenes: Challenges and Prospects for their Surface Modification Toward Future Biotechnological Application
    Authors:
    A. Szuplewska, D. Kulpińska, M. Jakubczak, A. Dybko, M. Chudy, A. Olszyna, Z. Brzózka, A.M. Jastrzębska
    Academic press:
    Advanced Drug Delivery Reviews (rok: 2021, tom: 182, strony: 114099), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.addr.2021.114099 - link to the publication

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