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New N-heterocyclic carbene gold complexes: from catalytic activity to medical application

2017/26/E/ST5/00510

Keywords

Descriptors

  • ST5_23: Chemia organiczna

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

Instytut Chemii Organicznej Polska Akademia Nauk

Voivodeship: mazowieckie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Michał Michalak

Number of co-investigators in the project: 9

Call

SONATA BIS 7 – announced on 2017-06-14

Amount awarded
2 548 600 PLN
Project start date
2018-04-26
Project end date
2024-10-25
Project duration
78 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (8)

  1. Base-Catalyzed, Solvent-Free Synthesis of Rigid V-Shaped Epoxydibenzo[b,f][1,5]diazocines

    Authors:
    Michał Michalak, Bartosz Bisek, Michał Nowacki, Marcin Górecki
    Academic press:
    The Journal of Organic Chemistry (year: 2021, volume: 86, pages: 8955–8969), Publisher: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.joc.1c00884 – link to the publication

  2. Chiral NHC Ligands for Enantioselective Gold(I) Catalysis Under Aerobic Conditions: the Importance of Conformational Flexibility and Steric Hindrance of NHC Ligand on Reactivity

    Authors:
    Michał Michalak, Paweł Czerwiński, Katarzyna Śniady-Maciążek, Szymon Musioł, Oksana Danylyuk, Michał Wierzbicki, Michele Tomasini, Albert Poater
    Academic press:
    Chemistry A Europen Journal (year: 2023, volume: 30, pages: e202303241), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1002/chem.202303241 – link to the publication

  3. NHC–BIAN–Cu(I)-Catalyzed Friedländer-Type Annulation of 2-Amino-3-(per)fluoroacetylpyridines with Alkynes on Water

    Authors:
    Magdalena Dolna , Michał Nowacki, Oksana Danylyuk, Artur Brotons-Rufes, Albert Poater*, and Michał Michalak*
    Academic press:
    The Journal of Organic Chemistry (year: 2022, volume: 87, pages: 6115-6136), Publisher: American Chemical Scciety
    Status:
    Published
    DOI:
    10.1021/acs.joc.2c00380 – link to the publication

  4. Epoxydibenzo[b,f][1,5]diazocines: From a Hidden Structural Motif to an Efficient Solvent-Free Synthetic Protocol

    Authors:
    Depa, Wojciech; Bisek, Bartosz; Górecki, Marcin; Michalak, Michał
    Academic press:
    Synthesis (year: 2022, volume: 54, pages: 2991–3004), Publisher: Georg Thieme Verlag
    Status:
    Published

  5. Synthetic Approaches to Chiral Non-C2-symmetric N-Heterocyclic Carbene Precursors

    Authors:
    Paweł J. Czerwiński; Michał Michalak
    Academic press:
    Synthesis (year: 2019, volume: 51, pages: 1689-1714), Publisher: Georg Thieme Verlag
    Status:
    Published
    DOI:
    10.1055/s-0037-1611733 – link to the publication

  6. NHC–Au–xanthate complexes

    Authors:
    Supratim Chakraborty, Aleksander Gorski, Oksana Danylyuk, Katarzyna Niemirowicz-Laskowska, Halina Car,Michał Michalak
    Academic press:
    Chemical Communications (year: 2025, volume: 61, pages: 1697–1700), Publisher: Royal Chemical Society
    Status:
    Published
    DOI:
    10.1039/D4CC05193A – link to the publication

  7. Chiral N-heterocyclic Carbene Gold Complexes: Synthesis and Applications in Catalysis

    Authors:
    Michał Michalak, Wioletta Kośnik
    Academic press:
    Catalyst (feature paper) (year: 2019, volume: 9, pages: 890-929), Publisher: MDPI, Basel, Switzerland
    Status:
    Published
    DOI:
    10.3390/catal9110890 – link to the publication

  8. Acenaphthene-Based N-Heterocyclic Carbene Metal Complexes: Synthesis and Application in Catalysis

    Authors:
    Paulina Baczewska, Katarzyna Sniady, Wioletta Kosnik, Michał Michalak
    Academic press:
    Catalysts (feature article) (year: 2021, volume: 9, pages: 972), Publisher: MDPI, Basel, Switzerland
    Status:
    Published
    DOI:
    10.3390/catal11080972 – link to the publication

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