Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

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New N-heterocyclic carbene gold complexes: from catalytic activity to medical application

2017/26/E/ST5/00510

Keywords:

N-heterocyclic carbene gold complexes enantioselectivity biological activity

Descriptors:

  • ST5_23:

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Instytut Chemii Organicznej Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Michał Michalak 

Number of co-investigators in the project: 9

Call: SONATA BIS 7 - announced on 2017-06-14

Amount awarded: 2 548 600 PLN

Project start date (Y-m-d): 2018-04-26

Project end date (Y-m-d): 2024-10-25

Project duration:: 60 months (the same as in the proposal)

Project status: Pending project

Project description

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Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (7)
  1. Base-Catalyzed, Solvent-Free Synthesis of Rigid V-Shaped Epoxydibenzo[b,f][1,5]diazocines
    Authors:
    Michał Michalak, Bartosz Bisek, Michał Nowacki, Marcin Górecki
    Academic press:
    The Journal of Organic Chemistry (rok: 2021, tom: 86, strony: 8955–8969), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acs.joc.1c00884 - link to the publication
  2. NHC–BIAN–Cu(I)-Catalyzed Friedländer-Type Annulation of 2-Amino-3-(per)fluoroacetylpyridines with Alkynes on Water
    Authors:
    Magdalena Dolna , Michał Nowacki, Oksana Danylyuk, Artur Brotons-Rufes, Albert Poater*, and Michał Michalak*
    Academic press:
    The Journal of Organic Chemistry (rok: 2022, tom: 87, strony: 6115-6136), Wydawca: American Chemical Scciety
    Status:
    Published
    DOI:
    10.1021/acs.joc.2c00380 - link to the publication
  3. Chiral NHC Ligands for Enantioselective Gold(I) Catalysis Under Aerobic Conditions: the Importance of Conformational Flexibility and Steric Hindrance of NHC Ligand on Reactivity
    Authors:
    Michał Michalak, Paweł Czerwiński, Katarzyna Śniady-Maciążek, Szymon Musioł, Oksana Danylyuk, Michał Wierzbicki, Michele Tomasini, Albert Poater
    Academic press:
    Chemistry A Europen Journal (rok: 2023, tom: 30, strony: e202303241), Wydawca: Wiley
    Status:
    Accepted for publication
    DOI:
    10.1002/chem.202303241 - link to the publication
  4. Acenaphthene-Based N-Heterocyclic Carbene Metal Complexes: Synthesis and Application in Catalysis
    Authors:
    Paulina Baczewska, Katarzyna Sniady, Wioletta Kosnik, Michał Michalak
    Academic press:
    Catalysts (feature article) (rok: 2021, tom: 9, strony: 972), Wydawca: MDPI, Basel, Switzerland
    Status:
    Published
    DOI:
    10.3390/catal11080972 - link to the publication
  5. Synthetic Approaches to Chiral Non-C2-symmetric N-Heterocyclic Carbene Precursors
    Authors:
    Paweł J. Czerwiński; Michał Michalak
    Academic press:
    Synthesis (rok: 2019, tom: 51, strony: 1689-1714), Wydawca: Georg Thieme Verlag
    Status:
    Published
    DOI:
    10.1055/s-0037-1611733 - link to the publication
  6. Epoxydibenzo[b,f][1,5]diazocines: From a Hidden Structural Motif to an Efficient Solvent-Free Synthetic Protocol
    Authors:
    Depa, Wojciech; Bisek, Bartosz; Górecki, Marcin; Michalak, Michał
    Academic press:
    Synthesis (rok: 2022, tom: 54, strony: 2991–3004), Wydawca: Georg Thieme Verlag
    Status:
    Published
    DOI:
    0.1055/s-0040-1719908 - link to the publication
  7. Chiral N-heterocyclic Carbene Gold Complexes: Synthesis and Applications in Catalysis
    Authors:
    Michał Michalak, Wioletta Kośnik
    Academic press:
    Catalyst (feature paper) (rok: 2019, tom: 9, strony: 890-929), Wydawca: MDPI, Basel, Switzerland
    Status:
    Published
    DOI:
    10.3390/catal9110890 - link to the publication

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