Combined urinary bladder cancer treatment with isothiocyanate-derived mercapturic acids and microtubule assembly modulators.

2017/26/D/NZ7/01152

Keywords

Descriptors

  • NZ7_14: Farmacja, farmakoterapia, farmakologia
  • NZ5_7: Leczenie chorób człowieka
  • NZ3_3: Apoptoza

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

Voivodeship: dolnośląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Mateusz Psurski

Number of co-investigators in the project: 5

Call

SONATA 13 – announced on 2017-06-14

Amount awarded
960 120 PLN
Project start date
2018-05-07
Project end date
2023-05-06
Project duration
60 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (2)

  1. Dipeptides of S-Substituted Dehydrocysteine as Artzyme Building Blocks: Synthesis, Complexing Abilities and Antiproliferative Properties

    Authors:
    Lenartowicz, Paweł; Psurski, Mateusz; Kotynia, Aleksandra; Pieniężna, Aleksandra; Cuprych, Monika; Poniatowska, Klaudia ; Brasuń, Justyna; Kafarski, Paweł
    Academic press:
    International Journal of Molecular Sciences (year: 2021, volume: 22, pages: 2168), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22042168 – link to the publication
  2. Distinct adaptive strategies to cisplatin, vinblastine and gemcitabine in a panel of chemoresistant bladder cancer cell lines

    Authors:
    Monika Cuprych-Belter; Agnieszka Łupicka-Słowik; Artur Anisiewicz; Martin Michaelis; Jindrich Cinatl Jr.; Mateusz Psurski
    Academic press:
    Cancer Drug Resistance (year: 2025, volume: 8, pages: 49), Publisher: OAE Publishing Inc.
    Status:
    Published
    DOI:
    10.20517/cdr.2025.95 – link to the publication

Articles in post-conference publications (1)

  1. Isothiocyanate-derived mercapturic acidspotentiate tubulin polymerizationinhibitors anticancer activity in urinarybladder cancer models (in vitro and invivo studies)

    Authors:
    Monika Cuprych; Mateusz Psurski
    Conference:
    ANNUAL CONGRESS OF THE EUROPEAN ASSOCIATION FOR CANCER RESEARCH (year: 2025, pages: 535-536), Publisher: FEBS Press
    Date:
    conference 16-19 czerwca 2025
    Status:
    Published
    DOI:
    link to the publication

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