Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Combined urinary bladder cancer treatment with isothiocyanate-derived mercapturic acids and microtubule assembly modulators.

2017/26/D/NZ7/01152

Keywords:

transitional cells carcinoma natural compounds cell cycle arrest mitotic catastrophe

Descriptors:

  • NZ7_14:
  • NZ5_7:
  • NZ3_3:

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Instytut Immunologii i Terapii Doświadczalnej im. Ludwika Hirszfelda Polskiej Akademii Nauk

woj. dolnośląskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Mateusz Psurski 

Number of co-investigators in the project: 5

Call: SONATA 13 - announced on 2017-06-14

Amount awarded: 960 120 PLN

Project start date (Y-m-d): 2018-05-07

Project end date (Y-m-d): 2023-05-06

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

  • Publication in academic press/journals (2)
  • Articles in post-conference publications (1)
  1. Distinct adaptive strategies to cisplatin, vinblastine and gemcitabine in a panel of chemoresistant bladder cancer cell lines
    Authors:
    Monika Cuprych-Belter; Agnieszka Łupicka-Słowik; Artur Anisiewicz; Martin Michaelis; Jindrich Cinatl Jr.; Mateusz Psurski
    Academic press:
    Cancer Drug Resistance (rok: 2025, tom: 8, strony: 49), Wydawca: OAE Publishing Inc.
    Status:
    Published
    DOI:
    10.20517/cdr.2025.95 - link to the publication
  2. Dipeptides of S-Substituted Dehydrocysteine as Artzyme Building Blocks: Synthesis, Complexing Abilities and Antiproliferative Properties
    Authors:
    Lenartowicz, Paweł; Psurski, Mateusz; Kotynia, Aleksandra; Pieniężna, Aleksandra; Cuprych, Monika; Poniatowska, Klaudia ; Brasuń, Justyna; Kafarski, Paweł
    Academic press:
    International Journal of Molecular Sciences (rok: 2021, tom: 22, strony: 2168), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms22042168 - link to the publication
  1. Isothiocyanate-derived mercapturic acidspotentiate tubulin polymerizationinhibitors anticancer activity in urinarybladder cancer models (in vitro and invivo studies)
    Authors:
    Monika Cuprych; Mateusz Psurski
    Conference:
    ANNUAL CONGRESS OF THE EUROPEAN ASSOCIATION FOR CANCER RESEARCH (rok: 2025, ), Wydawca: FEBS Press
    Data:
    konferencja 16-19 czerwca 2025
    Status:
    Published
    DOI:
    link to the publication

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