Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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The mechanical and spectroscopic study of two- and three-dimensional cell culture systems to assess molecular mechanism of glioblastoma multiforme development.

2017/26/D/ST4/00997

Keywords:

Glioblastoma multiforme mechanical properties of biological systems extracellular matrix cell-matrix mechanical interactions Raman spectroscopy spectroscopic markers biomaterials multivariate statistical analysis

Descriptors:

  • ST4_3: Molecular architecture and structure
  • ST5_11: Smart materials – self assembled materials, external stimuli-responsive materials
  • NZ1_3: Biophysics

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Instytut Fizyki Jądrowej im. Henryka Niewodniczańskiego Polskiej Akademii Nauk

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Katarzyna Pogoda 

Number of co-investigators in the project: 4

Call: SONATA 13 - announced on 2017-06-14

Amount awarded: 469 360 PLN

Project start date (Y-m-d): 2018-04-12

Project end date (Y-m-d): 2023-04-11

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Licencja na oprogramowanie OriginLab. (10 000 PLN)
  2. Komputer przenośny.
  3. Mikroskop optyczny do hodowli komórkowych. (15 000 PLN)

Information in the final report

  • Publication in academic press/journals (7)
  1. A Novel Method to Make Polyacrylamide Gels with Mechanical Properties Resembling those of Biological Tissues
    Authors:
    Katarzyna Pogoda, Elisabeth E Charrier, Paul A Janmey
    Academic press:
    Bio-protocol (rok: 2021, tom: 11, strony: N/A), Wydawca: N/A
    Status:
    Published
    DOI:
    10.21769/BioProtoc.4131 - link to the publication
  2. Dynamic Tuning of Viscoelastic Hydrogels with Carbonyl Iron Microparticles Reveals the Rapid Response of Cells to Three-Dimensional Substrate Mechanics
    Authors:
    Kiet A. Tran, Emile Kraus, Andy T. Clark, Alex Bennett, Katarzyna Pogoda, Xuemei Cheng, Andrejs Ce̅bers, Paul A. Janmey, and Peter A. Galie
    Academic press:
    ACS Applied Materials & Interfaces (rok: 2021, tom: 13, strony: 20947-20959), Wydawca: American Chemical Society
    Status:
    Published
    DOI:
    10.1021/acsami.0c21868 - link to the publication
  3. Elasticity-dependent response of malignant cells to viscous dissipation
    Authors:
    Elisabeth E Charrier, Katarzyna Pogoda, Robin Li, Rebecca G Wells, Paul A Janmey
    Academic press:
    Biomechanics and Modeling in Mechanobiology (rok: 2021, tom: 20, strony: 145-154), Wydawca: Springer Berlin Heidelberg
    Status:
    Published
    DOI:
    10.1007/s10237-020-01374-9 - link to the publication
  4. Loss of Vimentin Enhances Cell Motility through Small Confining Spaces
    Authors:
    Alison E Patteson, Katarzyna Pogoda, Fitzroy J Byfield, Kalpana Mandal, Zofia Ostrowska‐Podhorodecka, Elisabeth E Charrier, Peter A Galie, Piotr Deptuła, Robert Bucki, Christopher A McCulloch, Paul A Janmey
    Academic press:
    Small (rok: 2019, tom: 15, strony: 1903180), Wydawca: Wiley
    Status:
    Published
    DOI:
    10.1002/smll.201903180 - link to the publication
  5. Unique Role of Vimentin Networks in Compression Stiffening of Cells and Protection of Nuclei from Compressive Stress
    Authors:
    Katarzyna Pogoda, Fitzroy Byfield, Piotr Deptuła, Mateusz Cieśluk, Łukasz Suprewicz, Karol Skłodowski, Jordan L. Shivers, Anne van Oosten, Katrina Cruz, Ekaterina Tarasovetc, Ekaterina L. Grishchuk, Fred C. Mackintosh, Robert Bucki, Alison E. Patteson, and Paul A. Janmey
    Academic press:
    Nano letters (rok: 2022, tom: 22, strony: 4725–4732), Wydawca: ACS
    Status:
    Published
    DOI:
    10.1021/acs.nanolett.2c00736 - link to the publication
  6. Loops versus lines and the compression stiffening of cells
    Authors:
    M. C. Gandikota, Katarzyna Pogoda, Anne van Oosten, T. A. Engstrom, A. E. Patteson, P. A. Janmey and J. M. Schwarz
    Academic press:
    Soft Matter (rok: 2020, tom: 16, strony: 4389-4406), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/C9SM01627A - link to the publication
  7. Nanomechanics and Histopathology as Diagnostic Tools to Characterize Freshly Removed Human Brain Tumors
    Authors:
    Mateusz Cieśluk, Katarzyna Pogoda, Piotr Deptuła, Paulina Werel, Alina Kułakowska, Jan Kochanowicz, Zenon Mariak, Tomasz Łysoń, Joanna Reszeć, Robert Bucki
    Academic press:
    International Journal of Nanomedicine (rok: 2020, tom: 15, strony: 7509), Wydawca: Dove Press
    Status:
    Published
    DOI:
    10.2147/IJN.S270147 - link to the publication

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