Projects funded by the NCN


Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Modulation of stability of virions - a fight for and against viruses

2017/26/E/ST4/00041

Keywords:

bacteriophages electric field stabilization deactivation bioconjugation resistance

Descriptors:

  • ST4_13: Solid-state chemistry, surface physicochemistry
  • ST5_16:
  • ST3_15: Statistical physics of condensed matter, phase transitions, noise and fluctuations, etc.

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Instytut Chemii Fizycznej Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Jan Paczesny 

Number of co-investigators in the project: 10

Call: SONATA BIS 7 - announced on 2017-06-14

Amount awarded: 1 863 120 PLN

Project start date (Y-m-d): 2018-04-19

Project end date (Y-m-d): 2023-02-18

Project duration:: 58 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Mieszadło mechaniczne.
  2. Pompa strzykawkowa (17 000 PLN)
  3. Wzmacniacz napięcia 1000x (30 000 PLN)
  4. Mieszadło magnetyczne.
  5. Pompa próżniowa.
  6. Potencjostat wysokonapięciowy (95 000 PLN)
  7. Urządzenie wielofunkcyjne (drukarka + skaner).
  8. Części do specjalnie zaprojektowanych i wykonanych układów pomiarowych (25 000 PLN)
  9. Myjka ultradźwiękowa.
  10. Termomikser.
  11. Komputer PC (3 000 PLN)
  12. Zestaw pipet automatycznych.
  13. Chłodziarko-zamrażarka.
  14. Suszarka laboratoryjna.
  15. Wytrząsarka z wyposażeniem.

Information in the final report

  • Publication in academic press/journals (15)
  1. Fast and efficient deposition of broad range of analytes on substrates for surface enhanced Raman spectroscopy
    Authors:
    Łukasz Richter, Paweł Albrycht, Monika Księzopolska-Gocalska, Ewa Pobozy, Robert Bachlinski, Volodymyr Sashuk, Jan Paczesny, Robert Hołyst
    Academic press:
    Biosensors and Bioelectronics (rok: 2020, tom: 156, strony: 112124), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bios.2020.112124 - link to the publication
  2. Gold—Polyoxoborates Nanocomposite Prohibits Adsorption of Bacteriophages on Inner Surfaces of Polypropylene Labware and Protects Samples from Bacterial and Yeast Infections
    Authors:
    Mateusz Wdowiak, Enkhlin Ochirbat, Jan Paczesny
    Academic press:
    Viruses (rok: 2021, tom: 13(7), strony: 1206 (1-12)), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/v13071206 - link to the publication
  3. Application of Bacteriophages in Nanotechnology
    Authors:
    Jan Paczesny, Krzysztof Bielec
    Academic press:
    Nanomaterials (rok: 2020, tom: 10, strony: 1944), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nano10101944 - link to the publication
  4. Congo red protects bacteriophages against UV irradiation and allows for the simultaneous use of phages and UV for membrane sterilization
    Authors:
    Mateusz Wdowiak, Patryk A. Mierzejewski, Rafał Zbonikowski, Bartłomiej Bończaka and Jan Paczesny
    Academic press:
    Environmental Science Water Research & Technology (rok: 2023, tom: 9, strony: 696-706), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D2EW00913G - link to the publication
  5. Gold–Oxoborate Nanocomposite Coated Orthodontic Brackets Gain Antibacterial Properties while Remaining Safe for Eukaryotic Cells
    Authors:
    Jan Lyczek, Bartłomiej Bończak, Izabela Krzymińska, Konrad Gizyński, Jan Paczesny
    Academic press:
    Journal of Biomedical Materials Research: Part B - Applied Biomaterials (rok: 2023, tom: 111, strony: 996–1004), Wydawca: Willey
    Status:
    Published
    DOI:
    10.1002/jbm.b.35208 - link to the publication
  6. Heteroaggregation of virions and microplastics reduces the number of active bacteriophages in aqueous environments
    Authors:
    Enkhlin Ochirbat, Rafał Zbonikowski, Anna Sulicka, Bartłomiej Bończak, Magdalena Bonarowska, Marcin Łoś, Elżbieta Malinowska, Robert Hołyst, Jan Paczesny
    Academic press:
    Journal of Environmental Quality (rok: 2023, tom: NA, strony: NA), Wydawca: Willey
    Status:
    Published
    DOI:
    10.1002/jeq2.20459 - link to the publication
  7. Broad-spectrum nanoparticles against bacteriophage infections
    Authors:
    Łukasz Richter, Karolina Paszkowska, Urszula Cendrowska, Francesca Olgiati, Paulo Jacob Silva, Matteo Gasbarri, Zekiye Pelin Guven, Jan Paczesny, Francesco Stellacci
    Academic press:
    Nanoscale (rok: 2021, tom: 13, strony: 18684-18694), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D1NR04936D - link to the publication
  8. The activity of indigo carmine against bacteriophages - an edible antiphage agent
    Authors:
    Sada Raza, Bartłomiej Bończak, Nataliia Atamas, Aneta Karpińska, Tomasz Ratajczyk, Marcin Łoś, Robert Hołyst, Jan Paczesny
    Academic press:
    International Journal of Antimicrobial Agents (rok: 2023, tom: NA, strony: NA), Wydawca: Elsevier
    Status:
    Submitted
  9. Adsorption of bacteriophages on polypropylene labware affects the reproducibility of phage research
    Authors:
    Łukasz Richter, Karolina Księżarczyk, Karolina Paszkowska, Marta Janczuk Richter, Joanna Niedziółka-Jönsson, Jacek Gapiński, Marcin Łoś, Robert Hołyst, Jan Paczesny
    Academic press:
    Scientific Reports (rok: 2021, tom: NA, strony: Article number: 7387), Wydawca: NATURE PUBLISHING GROUP
    Status:
    Published
    DOI:
    10.1038/s41598-021-86571-x - link to the publication
  10. An Overview of Diverse Strategies To Inactivate Enterobacteriaceae-Targeting Bacteriophages
    Authors:
    Sada Raza, Mateusz Wdowiak and Jan Paczesny
    Academic press:
    EcoSal Plus (rok: 2023, tom: NA, strony: NA), Wydawca: American Society for Microbiology
    Status:
    Published
    DOI:
    10.1128/ecosalplus.esp-0019-2022 - link to the publication
  11. Resistance and Adaptation of Bacteria to Non-Antibiotic Antibacterial Agents: Physical Stressors, Nanoparticles, and Bacteriophages
    Authors:
    Sada Raza, Kinga Matuła, Sylwia Karoń, Jan Paczesny
    Academic press:
    Antibiotics (rok: 2021, tom: 10(4), strony: 435 (1-24)), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/antibiotics10040435 - link to the publication
  12. Storage of Energy in Constrained Non-Equilibrium Systems
    Authors:
    Yirui Zhang, Konrad Gizynski, Anna Maciołek, Robert Hołyst
    Academic press:
    Entropy (rok: 2020, tom: 22, strony: 557), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/e22050557 - link to the publication
  13. The Effect of Zero-Valent Iron Nanoparticles (nZVI) on Bacteriophages
    Authors:
    Sada Raza, Michał Folga, Marcin Łoś, Zenon Foltynowicz, Jan Paczesny
    Academic press:
    Viruses (rok: 2022, tom: 14(5), strony: 867), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/v14050867 - link to the publication
  14. Enhancing the Stability of Bacteriophages Using Physical, Chemical, and Nano-Based Approaches: A Review
    Authors:
    Mateusz Wdowiak, Jan Paczesny, Sada Raza
    Academic press:
    Pharmaceutics (rok: 2022, tom: 16(9), strony: 1936), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics14091936 - link to the publication
  15. Recent Progress in the Detection of Bacteria Using Bacteriophages: A Review
    Authors:
    Jan Paczesny, Łukasz Richter, Robert Hołyst
    Academic press:
    Viruses (rok: 2020, tom: 12, strony: 845), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/v12080845 - link to the publication