Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Modulation of stability of virions - a fight for and against viruses

2017/26/E/ST4/00041

Keywords:

bacteriophages electric field stabilization deactivation bioconjugation resistance

Descriptors:

  • ST4_13: Solid-state chemistry, surface physicochemistry
  • ST5_16:
  • ST3_15: Statistical physics of condensed matter, phase transitions, noise and fluctuations, etc.

Panel:

ST4 - Chemistry: physical chemistry/chemical physics, theoretical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, method development

Host institution :

Instytut Chemii Fizycznej Polskiej Akademii Nauk

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr Jan Paczesny 

Number of co-investigators in the project: 10

Call: SONATA BIS 7 - announced on 2017-06-14

Amount awarded: 1 863 120 PLN

Project start date (Y-m-d): 2018-04-19

Project end date (Y-m-d): 2023-02-18

Project duration:: 58 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Mieszadło magnetyczne.
  2. Chłodziarko-zamrażarka.
  3. Suszarka laboratoryjna.
  4. Termomikser.
  5. Zestaw pipet automatycznych.
  6. Komputer PC (3 000 PLN)
  7. Pompa próżniowa.
  8. Wytrząsarka z wyposażeniem.
  9. Myjka ultradźwiękowa.
  10. Urządzenie wielofunkcyjne (drukarka + skaner).
  11. Wzmacniacz napięcia 1000x (30 000 PLN)
  12. Części do specjalnie zaprojektowanych i wykonanych układów pomiarowych (25 000 PLN)
  13. Mieszadło mechaniczne.
  14. Pompa strzykawkowa (17 000 PLN)
  15. Potencjostat wysokonapięciowy (95 000 PLN)

Information in the final report

  • Publication in academic press/journals (15)
  1. An Overview of Diverse Strategies To Inactivate Enterobacteriaceae-Targeting Bacteriophages
    Authors:
    Sada Raza, Mateusz Wdowiak and Jan Paczesny
    Academic press:
    EcoSal Plus (rok: 2023, tom: NA, strony: NA), Wydawca: American Society for Microbiology
    Status:
    Published
    DOI:
    10.1128/ecosalplus.esp-0019-2022 - link to the publication
  2. Application of Bacteriophages in Nanotechnology
    Authors:
    Jan Paczesny, Krzysztof Bielec
    Academic press:
    Nanomaterials (rok: 2020, tom: 10, strony: 1944), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/nano10101944 - link to the publication
  3. Enhancing the Stability of Bacteriophages Using Physical, Chemical, and Nano-Based Approaches: A Review
    Authors:
    Mateusz Wdowiak, Jan Paczesny, Sada Raza
    Academic press:
    Pharmaceutics (rok: 2022, tom: 16(9), strony: 1936), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/pharmaceutics14091936 - link to the publication
  4. Adsorption of bacteriophages on polypropylene labware affects the reproducibility of phage research
    Authors:
    Łukasz Richter, Karolina Księżarczyk, Karolina Paszkowska, Marta Janczuk Richter, Joanna Niedziółka-Jönsson, Jacek Gapiński, Marcin Łoś, Robert Hołyst, Jan Paczesny
    Academic press:
    Scientific Reports (rok: 2021, tom: NA, strony: Article number: 7387), Wydawca: NATURE PUBLISHING GROUP
    Status:
    Published
    DOI:
    10.1038/s41598-021-86571-x - link to the publication
  5. Broad-spectrum nanoparticles against bacteriophage infections
    Authors:
    Łukasz Richter, Karolina Paszkowska, Urszula Cendrowska, Francesca Olgiati, Paulo Jacob Silva, Matteo Gasbarri, Zekiye Pelin Guven, Jan Paczesny, Francesco Stellacci
    Academic press:
    Nanoscale (rok: 2021, tom: 13, strony: 18684-18694), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D1NR04936D - link to the publication
  6. Fast and efficient deposition of broad range of analytes on substrates for surface enhanced Raman spectroscopy
    Authors:
    Łukasz Richter, Paweł Albrycht, Monika Księzopolska-Gocalska, Ewa Pobozy, Robert Bachlinski, Volodymyr Sashuk, Jan Paczesny, Robert Hołyst
    Academic press:
    Biosensors and Bioelectronics (rok: 2020, tom: 156, strony: 112124), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.bios.2020.112124 - link to the publication
  7. Storage of Energy in Constrained Non-Equilibrium Systems
    Authors:
    Yirui Zhang, Konrad Gizynski, Anna Maciołek, Robert Hołyst
    Academic press:
    Entropy (rok: 2020, tom: 22, strony: 557), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/e22050557 - link to the publication
  8. Congo red protects bacteriophages against UV irradiation and allows for the simultaneous use of phages and UV for membrane sterilization
    Authors:
    Mateusz Wdowiak, Patryk A. Mierzejewski, Rafał Zbonikowski, Bartłomiej Bończaka and Jan Paczesny
    Academic press:
    Environmental Science Water Research & Technology (rok: 2023, tom: 9, strony: 696-706), Wydawca: Royal Society of Chemistry
    Status:
    Published
    DOI:
    10.1039/D2EW00913G - link to the publication
  9. Heteroaggregation of virions and microplastics reduces the number of active bacteriophages in aqueous environments
    Authors:
    Enkhlin Ochirbat, Rafał Zbonikowski, Anna Sulicka, Bartłomiej Bończak, Magdalena Bonarowska, Marcin Łoś, Elżbieta Malinowska, Robert Hołyst, Jan Paczesny
    Academic press:
    Journal of Environmental Quality (rok: 2023, tom: NA, strony: NA), Wydawca: Willey
    Status:
    Published
    DOI:
    10.1002/jeq2.20459 - link to the publication
  10. Resistance and Adaptation of Bacteria to Non-Antibiotic Antibacterial Agents: Physical Stressors, Nanoparticles, and Bacteriophages
    Authors:
    Sada Raza, Kinga Matuła, Sylwia Karoń, Jan Paczesny
    Academic press:
    Antibiotics (rok: 2021, tom: 10(4), strony: 435 (1-24)), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/antibiotics10040435 - link to the publication
  11. The Effect of Zero-Valent Iron Nanoparticles (nZVI) on Bacteriophages
    Authors:
    Sada Raza, Michał Folga, Marcin Łoś, Zenon Foltynowicz, Jan Paczesny
    Academic press:
    Viruses (rok: 2022, tom: 14(5), strony: 867), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/v14050867 - link to the publication
  12. The activity of indigo carmine against bacteriophages - an edible antiphage agent
    Authors:
    Sada Raza, Bartłomiej Bończak, Nataliia Atamas, Aneta Karpińska, Tomasz Ratajczyk, Marcin Łoś, Robert Hołyst, Jan Paczesny
    Academic press:
    International Journal of Antimicrobial Agents (rok: 2023, tom: NA, strony: NA), Wydawca: Elsevier
    Status:
    Submitted
    DOI:
    brak - link to the publication
  13. Gold—Polyoxoborates Nanocomposite Prohibits Adsorption of Bacteriophages on Inner Surfaces of Polypropylene Labware and Protects Samples from Bacterial and Yeast Infections
    Authors:
    Mateusz Wdowiak, Enkhlin Ochirbat, Jan Paczesny
    Academic press:
    Viruses (rok: 2021, tom: 13(7), strony: 1206 (1-12)), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/v13071206 - link to the publication
  14. Gold–Oxoborate Nanocomposite Coated Orthodontic Brackets Gain Antibacterial Properties while Remaining Safe for Eukaryotic Cells
    Authors:
    Jan Lyczek, Bartłomiej Bończak, Izabela Krzymińska, Konrad Gizyński, Jan Paczesny
    Academic press:
    Journal of Biomedical Materials Research: Part B - Applied Biomaterials (rok: 2023, tom: 111, strony: 996–1004), Wydawca: Willey
    Status:
    Published
    DOI:
    10.1002/jbm.b.35208 - link to the publication
  15. Recent Progress in the Detection of Bacteria Using Bacteriophages: A Review
    Authors:
    Jan Paczesny, Łukasz Richter, Robert Hołyst
    Academic press:
    Viruses (rok: 2020, tom: 12, strony: 845), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/v12080845 - link to the publication

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