Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Synthesis of new derivatives of alloxanthoxyletins with fatty acids and the evaluation of their antiproliferative activity.

2017/25/N/NZ7/01583

Keywords:

Alloxanthoxyletin fatty acids cytotoxicity

Descriptors:

  • ST5_16:
  • NZ7_14: Pharmacy, pharmacotherapy, pharmacology

Panel:

NZ7 - Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution :

Warszawski Uniwersytet Medyczny, Wydział Lekarski

woj. mazowieckie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Michał Jóźwiak 

Number of co-investigators in the project: 2

Call: PRELUDIUM 13 - announced on 2017-03-15

Amount awarded: 155 142 PLN

Project start date (Y-m-d): 2018-01-26

Project end date (Y-m-d): 2021-01-25

Project duration:: 36 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Wirówka (46 110 PLN)

Information in the final report

  • Publication in academic press/journals (3)
  1. Anticancer activities of fatty acids and their heterocyclic derivatives
    Authors:
    Jóźwiak Michał, Filipowska Anna, Fiorino Ferdinando, Struga Marta
    Academic press:
    European Journal of Pharmacology (rok: 2020, tom: 871, strony: 172937), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.ejphar.2020.172937 - link to the publication
  2. Anticancer effects of alloxanthoxyletin and fatty acids esters – In vitro study on cancer HTB-140 and A549 cells
    Authors:
    Jóźwiak, Michał Struga, Marta Roszkowski, Piotr Filipek, Agnieszka Nowicka, Grażyna Olejarz, Wioletta
    Academic press:
    Biomedicine & Pharmacotherapy (rok: 2019, tom: 110, strony: 618-630), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.biopha.2018.12.005 - link to the publication
  3. Synthesis and anticancer effects of α-lipoic ester of alloxanthoxyletin
    Authors:
    Olejarz Wioletta, Wrzosek Małgorzata, Jóźwiak Michał, Grosicka-Maciąg Emilia, Roszkowski Piotr, Filipek Agnieszka, Cychol Agnieszka, Nowicka Grażyna, Struga Marta
    Academic press:
    Medicinal Chemistry Research (rok: 2019, tom: 28, strony: 788-798), Wydawca: Springer
    Status:
    Published
    DOI:
    10.1007/s00044-019-02335-3 - link to the publication

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