Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

Equipment

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Alternative pathways of vitamin D signaling

2017/25/B/NZ3/00431

Keywords:

vitamin D VDR PDIA3

Descriptors:

  • NZ1_1: Molecular biology
  • NZ3_2: Cell physiology
  • NZ3_1: Cell biology

Panel:

NZ3 - Cellular and developmental biology: cell biology, developmental biology, ageing biology, neurobiology

Host institution :

Gdański Uniwersytet Medyczny, Wydział Lekarski

woj. pomorskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

prof. Michał Żmijewski 

Number of co-investigators in the project: 7

Call: OPUS 13 - announced on 2017-03-15

Amount awarded: 1 700 400 PLN

Project start date (Y-m-d): 2018-02-09

Project end date (Y-m-d): 2023-02-08

Project duration:: 60 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Automatyczny mikroskop fluorescencyjny z komorą do inkubacji oraz oprzyrządowaniem (450 000 PLN)
  2. Fotoradiometr.
  3. Komputer (6 000 PLN)
  4. Monitor.
  5. Oprogramowanie Graph Pad Prism 7 (na 5 stanowisk) (4 000 PLN)

Information in the final report

  • Publication in academic press/journals (9)
  1. PDIA3 knockout abrogate effects of 1,25(OH)2D3 on cellular respiration and glycolysis in squamous cell carcinoma
    Authors:
    Joanna I. Nowak, Anna Olszewska, Oliwia Król, Michał A. Żmijewski
    Academic press:
    Scientific Reports (rok: 2023, ), Wydawca: Nature
    Status:
    Submitted
    DOI:
    brak - link to the publication
  2. The Effects of Vitamin D on the Expression of IL-33 and Its Receptor ST2 in Skin Cells; Potential Implication for Psoriasis
    Authors:
    Wierzbicka JM, Piotrowska A, Purzycka-Bohdan D, Olszewska A, Nowak JI, Szczerkowska-Dobosz A, Nedoszytko B, Nowicki RJ, Żmijewski MA.
    Academic press:
    Int J Mol Sci. (rok: 2021, tom: 22(23), strony: 45308), Wydawca: MPDI
    Status:
    Published
    DOI:
    10.3390/ijms222312907 - link to the publication
  3. Mitochondrial potassium channels: A novel calcitriol target
    Authors:
    Olszewska AM, Sieradzan AK, Bednarczyk P, Szewczyk A, Żmijewski MA.
    Academic press:
    Cell Mol Biol Lett. (rok: 2022, tom: 27(3), strony: 45311), Wydawca: Springer Nature BMC
    Status:
    Published
    DOI:
    10.1186/s11658-021-00299-0 - link to the publication
  4. Dissection of an impact of VDR and RXRA on genomic activity of 1,25(OH)2D3 in A431 squamous cell carcinoma
    Authors:
    Olszewska AM, Nowak JI, Myszczynski K, Słominski AT, Żmijewski MA
    Academic press:
    Journal of Steroid Biochemistry and Molecular Biology (rok: 2023, ), Wydawca: Elsevier
    Status:
    Submitted
    DOI:
    brak - link to the publication
  5. Nongenomic Activities of Vitamin D
    Authors:
    Żmijewski MA
    Academic press:
    Nutrients (rok: 2022, tom: 14(23)5104, strony: 45311), Wydawca: MPDI
    Status:
    Published
    DOI:
    10.3390/nu14235104 - link to the publication
  6. The Role of Classical and Novel Forms of Vitamin D in the Pathogenesis and Progression of Nonmelanoma Skin Cancers
    Authors:
    5.Slominski AT, Brożyna AA, Zmijewski MA, Janjetovic Z, Kim TK, Slominski RM, Tuckey RC, Mason RS, Jetten AM, Guroji P, Reichrath J, Elmets C, Athar M.
    Academic press:
    Adv Exp Med Biol (rok: 2020, tom: 1268, strony: 257-283), Wydawca: Springer Nature Switzerland AG
    Status:
    Published
    DOI:
    0.1007/978-3-030-46227-7_13 - link to the publication
  7. Vitamin D receptor(s): In the nucleus but also at membranes?
    Authors:
    Michal A Zmijewski, Carsten Carlberg
    Academic press:
    Exp Dermatol (rok: 2020, tom: 29(9), strony: 876-884), Wydawca: John Wiley & Sons Ltd
    Status:
    Published
    DOI:
    10.1111/exd.14147 - link to the publication
  8. Different impact of vitamin D on mitochondrial activity and morphology in normal and malignant keratinocytes, the role of genomic pathway
    Authors:
    Anna M. Olszewska, Joanna I. Nowak, Oliwia Król, Damian Flis, Michał A. Zmijewski
    Academic press:
    Free Radical Biology and Medicine (rok: 2023, ), Wydawca: Elsevier
    Status:
    Submitted
    DOI:
    brak - link to the publication
  9. PDIA3 modulates genomic response to 1,25-dihydroxyvitamin D3 in squamous cell carcinoma of the skin
    Authors:
    Nowak JI, Olszewska AM, Piotrowska A, Myszczyński K, Domżalski P, Żmijewski MA.
    Academic press:
    Steroids (rok: 2023, ), Wydawca: Elsevier
    Status:
    Accepted for publication
    DOI:
    10.1016/j.steroids.2023.109288 - link to the publication

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