Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Analysis of human coronavirus OC43 and Zika virus internalization routes in cells. Inhibition of the early steps of infection by intracellular pH tuning.

2017/25/N/NZ6/01310

Keywords:

OC43 coronavirus HCoV-OC43 Zika virus ZIKV intracellular trafficking pH dependence endosome recycling

Descriptors:

  • NZ1_10: Microbiology
  • NZ6_5: Virology
  • NZ3_14: Other related subjects

Panel:

NZ6 - Human and animal immunology and infection: immunity, immune disorders, immunotherapy, infectious and invasive diseases, microbiology, transplantology, allergology

Host institution :

Uniwersytet Jagielloński, Wydział Biochemii, Biofizyki i Biotechnologii

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

Katarzyna Owczarek 

Number of co-investigators in the project: 2

Call: PRELUDIUM 13 - announced on 2017-03-15

Amount awarded: 59 960 PLN

Project start date (Y-m-d): 2018-03-05

Project end date (Y-m-d): 2019-06-04

Project duration:: 15 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Zewnętrzny dysk pamięci (233 PLN)
  2. Komputer osobisty (3 500 PLN)

Information in the final report

  • Publication in academic press/journals (2)
  1. Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells
    Authors:
    Artur Szczepański, Katarzyna Owczarek, Aleksandra Milewska, Zbigniew Baster, Zenon Rajfur, Judy A. Mitchell and Krzysztof Pyrć
    Academic press:
    Veterinary Research (rok: 2018, tom: 2,07986111111111, strony: 45305), Wydawca: BioMed Central Ltd, Part of Springer Nature.
    Status:
    Published
    DOI:
    10.1186/s13567-018-0551-9 - link to the publication
  2. Zika virus: mapping and reprogramming the entry
    Authors:
    Katarzyna Owczarek, Yuliya Chykunova, Christian Jassoy, Beata Maksym, Zenon Rajfur, Krzysztof Pyrć
    Academic press:
    Cell Communication and Signalling (rok: 2019, tom: 17, strony: 41), Wydawca: BioMed Central Ltd, Part of Springer Nature.
    Status:
    Published
    DOI:
    10.1186/s12964-019-0349-z - link to the publication

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