Effect of high intensity interval training on mechanisms of neuroplasticity and psychomotor behaviours in Parkinson's disease patients: a randomized study with 1-year follow up

2017/25/B/NZ7/02795

Keywords

Descriptors

  • NZ7_3: Promocja zdrowia, kultura fizyczna
  • NZ7_7: Rehabilitacja

Panel

NZ7 – Diagnostic tools, therapies and public health: public health, epidemiology, environmental health risks and occupational medicine, medical ethics, drug discovery and therapies, pharmacology

Host institution

AKADEMIA WYCHOWANIA FIZYCZNEGO WE WROCŁAWIU, Wydział Fizjoterapii

Voivodeship: dolnośląskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

prof. Jarosław Marusiak

Number of co-investigators in the project: 13

Call

OPUS 13 – announced on 2017-03-15

Amount awarded
1 959 900 PLN
Project start date
2018-02-15
Project end date
2022-02-14
Project duration
48 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (4)

  1. 12-Week Aerobic Interval Training boosts Neuroplasticity and Motor Function in Parkinson's Disease: Insights from BDNF, [18F]fluorodopa PET/CT, and EEG

    Authors:
    Lorek K, Chalimoniuk M, Langfort J, Mączewska J, Królicki L, Markowska K, Budrewicz S, Koszewicz M, Wroński Z, Marusiak J
    Academic press:
    Neurorehabilitation and Neural Repair (year: 2025, volume: 39, pages: 867-882), Publisher: SAGE Publishing
    Status:
    Published
    DOI:
    10.1177/15459683251360729 – link to the publication
  2. Association between the Val66Met (rs6265) polymorphism of the brain-derived neurotrophic factor (BDNF) gene, BDNF protein level in the blood and the risk of developing early‑onset Parkinson's disease

    Authors:
    Przybylska I, Marusiak J, Toczyłowska B, Stępień A, Brodacki B, Langfort J, Chalimoniuk M
    Academic press:
    Acta Neurobiologiae Experimentalis (year: 2024, volume: 11, pages: 296-308), Publisher: Nencki Institute of Experimental Biology Polish Academy of Sciences
    Status:
    Published
    DOI:
    10.55782/ane-2024-2476. – link to the publication
  3. Slowing of EEG waves correlates with striatal [18 F]fluorodopa PET/CT uptake and executive dysfunction in Parkinson's disease.

    Authors:
    Lorek K, Mączewska J, Królicki L, Siemiatycka M, Chalimoniuk M, Kisiel-Sajewicz K, Marusiak J.
    Academic press:
    European Journal of Neuroscience (year: 2023, volume: 58(9), pages: 4070-4083), Publisher: Wiley
    Status:
    Published
    DOI:
    10.1111/ejn.16156 – link to the publication
  4. Motor cortex activation mediates associations between striatal dopamine depletion and manual dexterity in Parkinson's disease

    Authors:
    Lorek K, Mączewska J, Królicki L, Chalimoniuk M, Markowska K, Budrewicz S, Koszewicz M, Szumowski Ł, Marusiak J
    Academic press:
    Parkinsonism and Related Disorders (year: 2024, volume: 125, pages: 107049), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.parkreldis.2024.107049. – link to the publication

Articles in post-conference publications (1)

  1. Circutlating levels of BDNF and microRNAs are associated with progression of idiopathic Parkinsons disease

    Authors:
    Małczynska P., Brodacki B., Langfort J., Chalimoniuk M.,
    Conference:
    14th International Symposium Molecular basis of pathology and therapy in neurological disorders (year: 2018, pages: 240), Publisher: Termedia
    Date:
    conference 25-26.10.2018 Warszawa Polska
    Status:
    Published

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