Projects funded by the NCN

Information on the principal investigator and host institution

Information of the project and the call

Keywords

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Modification of physico-chemical properties of lung fibroblasts in response to chemical modification of two- and three-dimensional substrates with controlled elasticity

2017/25/B/ST5/00575

Keywords:

idiopathic lung diseases physicochemical properties of cells porous elastomer substrates

Descriptors:

  • ST5_3: Surface modification
  • ST5_9: Biomaterials, biocompatible materials
  • NZ5_5: Diagnostics in human diseases

Panel:

ST5 - Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution :

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

woj. małopolskie

Other projects carried out by the institution 

Principal investigator (from the host institution):

dr hab. Joanna Raczkowska 

Number of co-investigators in the project: 7

Call: OPUS 13 - announced on 2017-03-15

Amount awarded: 1 152 400 PLN

Project start date (Y-m-d): 2018-02-13

Project end date (Y-m-d): 2021-12-12

Project duration:: 46 months (the same as in the proposal)

Project status: Project settled

Project description

Download the project description in a pdf file

Note - project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Fotoploter (65 000 PLN)
  2. Wirówka laboratoryjna (19 803 PLN)
  3. Dysk zewnętrzny.
  4. Naczynie Dewara (6 000 PLN)
  5. Kostka filtrowa do mikroskopu Olympus (5 060 PLN)
  6. Profilometr DektakXT (425 000 PLN)
  7. Laptop (10 000 PLN)
  8. Laptop typu 2 w 1.

Information in the final report

  • Publication in academic press/journals (4)
  • Articles in post-conference publications (5)
  1. Discrimination between NSIP- and IPF-derived fibroblasts based on multi-parameter characterization of their growth, morphology and physic-chemical properties
    Authors:
    Barbara Orzechowska, Kamil Awsiuk, Dawid Wnuk, Joanna Pabijan, Tomasz Stachura, Jerzy Soja, Krzysztof Sładek, Joanna Raczkowska
    Academic press:
    International Journal of Molecular Sciences (rok: 2022, tom: 23, strony: 2162), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23042162 - link to the publication
  2. Effect of substrate stiffness on physico-chemical properties of normal and fibrotic lung fibroblasts
    Authors:
    Joanna Raczkowska, Barbara Orzechowska, Sabina Patryas, Kamil Awsiuk, Andrzej Kubiak, Masaya Kinoshita, Masami Okamoto, Justyna Bobrowska, Tomasz Stachura, Jerzy Soja, Krzysztof Sładek, Malgorzata Lekka
    Academic press:
    Materials (rok: 2020, tom: 13, strony: 4495), Wydawca: MDPI
    Status:
    Published
    DOI:
    10.3390/ma13204495 - link to the publication
  3. O podłożach polimerowych, czyli jak skutecznie walczyć z chorobami płuc
    Authors:
    Joanna Raczkowska, Kamil Awsiuk, Tomasz Stachura
    Academic press:
    Projektor Jagielloński (rok: 2021, tom: 1, strony: 34-35), Wydawca: Uniwersytet Jagielloński
    Status:
    Published
    DOI:
    brak - link to the publication
  4. Effect of tuned elasticity and chemical modification of substrate on fibrotic and healthy lung fibroblasts
    Authors:
    Joanna Raczkowska, Barbara Orzechowska
    Academic press:
    Micron (rok: 2020, tom: 139C, strony: 102948), Wydawca: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.micron.2020.102948 - link to the publication
  1. Multi-parameter discrimination between NSIP- and IPF-derived fibroblasts based on their physic-chemical properties
    Authors:
    J. Raczkowska, B. Orzechowska, K. Awsiuk
    Conference:
    5th International Conference on Applied Surface Science (rok: 2022, ), Wydawca: Elsevier
    Data:
    konferencja 25 -28.04
    Status:
    Submitted
  2. Discrimination Between Cells from Different Interstitial Lung Diseases by Controlled Interactions with Bio-interfaces of Polymer Coatings
    Authors:
    Joanna Raczkowska
    Conference:
    EastWest Chemistry Conference (rok: 2018, ), Wydawca: Komitet organizacyjny
    Data:
    konferencja 10-12 października 2018
    Status:
    Published
  3. Własności fizykochemiczne fibroblastów płucnych na podłożach o kontrolowanej elastyczności
    Authors:
    Joanna Raczkowska, Barbara Orzechowska
    Conference:
    45 Zjazd Fizyków Polskich (rok: 2019, ), Wydawca: Komitet organizacyjny
    Data:
    konferencja 13-18 wrzesień
    Status:
    Published
  4. Change in physicochemical properties in the lungs in response to chemically modified two-dimensional substrates with controlled elasticity
    Authors:
    Barbara Orzechowska, Joanna Raczkowska, Małgorzata Lekka
    Conference:
    Cell Physics (rok: 2019, ), Wydawca: Komitet organizacyjny
    Data:
    konferencja 9-11 pażdziernik
    Status:
    Published
  5. Identification of IPF- and NSIP-derived fibroblasts based on the analysis of their physical and chemical properties on substrates with modified mechanical, chemical and topographical properties
    Authors:
    J. Raczkowska, B. Orzechowska, K. Awsiuk, N. Janiszewska
    Conference:
    Advances in surfaces, interfaces, and interphases (rok: 2022, ), Wydawca: Elsevier
    Data:
    konferencja 15-18.05
    Status:
    Submitted

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