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Modification of physico-chemical properties of lung fibroblasts in response to chemical modification of two- and three-dimensional substrates with controlled elasticity

2017/25/B/ST5/00575

Keywords

Descriptors

  • ST5_3: Modyfikacja powierzchni materiałów
  • ST5_9: Materiały do konstrukcji sensorów
  • NZ5_5: Diagnostyka chorób człowieka

Panel

ST5 – Materials: materials synthesis, structure-properties relations, advanced and functional materials with designed properties, (macro)molecular architecture, material engineering

Host institution

Uniwersytet Jagielloński, Wydział Fizyki, Astronomii i Informatyki Stosowanej

Voivodeship: małopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr hab. Joanna Raczkowska

Number of co-investigators in the project: 7

Call

OPUS 13 – announced on 2017-03-15

Amount awarded
1 152 400 PLN
Project start date
2018-02-13
Project end date
2021-12-12
Project duration
46 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Equipment purchased [PL]

  1. Dysk zewnętrzny.
  2. Fotoploter. Cost: 65 000 PLN
  3. Kostka filtrowa do mikroskopu Olympus. Cost: 5 060 PLN
  4. Laptop. Cost: 10 000 PLN
  5. Laptop typu 2 w 1.
  6. Naczynie Dewara. Cost: 6 000 PLN
  7. Profilometr DektakXT. Cost: 425 000 PLN
  8. Wirówka laboratoryjna. Cost: 19 803 PLN

Information in the final report

Publication in academic press/journals (4)

  1. O podłożach polimerowych, czyli jak skutecznie walczyć z chorobami płuc

    Authors:
    Joanna Raczkowska, Kamil Awsiuk, Tomasz Stachura
    Academic press:
    Projektor Jagielloński (year: 2021, volume: 1, pages: 34-35), Publisher: Uniwersytet Jagielloński
    Status:
    Published

  2. Discrimination between NSIP- and IPF-derived fibroblasts based on multi-parameter characterization of their growth, morphology and physic-chemical properties

    Authors:
    Barbara Orzechowska, Kamil Awsiuk, Dawid Wnuk, Joanna Pabijan, Tomasz Stachura, Jerzy Soja, Krzysztof Sładek, Joanna Raczkowska
    Academic press:
    International Journal of Molecular Sciences (year: 2022, volume: 23, pages: 2162), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ijms23042162 – link to the publication

  3. Effect of tuned elasticity and chemical modification of substrate on fibrotic and healthy lung fibroblasts

    Authors:
    Joanna Raczkowska, Barbara Orzechowska
    Academic press:
    Micron (year: 2020, volume: 139C, pages: 102948), Publisher: Elsevier
    Status:
    Published
    DOI:
    10.1016/j.micron.2020.102948 – link to the publication

  4. Effect of substrate stiffness on physico-chemical properties of normal and fibrotic lung fibroblasts

    Authors:
    Joanna Raczkowska, Barbara Orzechowska, Sabina Patryas, Kamil Awsiuk, Andrzej Kubiak, Masaya Kinoshita, Masami Okamoto, Justyna Bobrowska, Tomasz Stachura, Jerzy Soja, Krzysztof Sładek, Malgorzata Lekka
    Academic press:
    Materials (year: 2020, volume: 13, pages: 4495), Publisher: MDPI
    Status:
    Published
    DOI:
    10.3390/ma13204495 – link to the publication

Articles in post-conference publications (3)

  1. Discrimination Between Cells from Different Interstitial Lung Diseases by Controlled Interactions with Bio-interfaces of Polymer Coatings

    Authors:
    Joanna Raczkowska
    Conference:
    EastWest Chemistry Conference (year: 2018, pages: 127), Publisher: Komitet organizacyjny
    Date:
    conference 10-12 października 2018
    Status:
    Published

  2. Własności fizykochemiczne fibroblastów płucnych na podłożach o kontrolowanej elastyczności

    Authors:
    Joanna Raczkowska, Barbara Orzechowska
    Conference:
    45 Zjazd Fizyków Polskich (year: 2019, pages: 314), Publisher: Komitet organizacyjny
    Date:
    conference 13-18 wrzesień
    Status:
    Published

  3. Change in physicochemical properties in the lungs in response to chemically modified two-dimensional substrates with controlled elasticity

    Authors:
    Barbara Orzechowska, Joanna Raczkowska, Małgorzata Lekka
    Conference:
    Cell Physics (year: 2019, pages: 168), Publisher: Komitet organizacyjny
    Date:
    conference 9-11 pażdziernik
    Status:
    Published

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