Mechanism of alternative splicing regulation by MBNL proteins

2017/24/C/NZ1/00112

Keywords

Descriptors

  • NZ1_1: Biologia molekularna
  • NZ1_2: Biochemia
  • NZ2_2: Genomika, transkryptomika i epigenomika

Panel

NZ1 – Molecular biology, structural biology, biotechnology: molecular biology, structural biology, biotechnology

Host institution

Uniwersytet im. Adama Mickiewicza w Poznaniu, Wydział Biologii

Voivodeship: wielkopolskie

Other projects carried out by the institution »

Principal investigator (from the host institution)

dr Katarzyna Magdalena Taylor

Number of co-investigators in the project: 1

Call

SONATINA 1 – announced on 2016-12-15

Amount awarded
996 346 PLN
Project start date
2017-10-16
Project end date
2020-10-15
Project duration
36 months (the same as in the proposal)
Project status
Project settled

Project description

Download the project description in a pdf file

Note — project descriptions were prepared by the authors of the applications themselves and placed in the system in an unchanged form.

Information in the final report

Publication in academic press/journals (5)

  1. Muscleblind-like 2 controls the hypoxia response of cancer cells

    Authors:
    Fischer S., Liddo A.D., Taylor K., Gerhardus A.S., Sobczak K., Zarnack K., Weigand J.E.
    Academic press:
    RNA (year: 2020, volume: 0, pages: 0), Publisher: Cold Spring Harbor Laboratory Press
    Status:
    Published
    DOI:
    10.1261/rna.073353.119 – link to the publication
  2. Global Increase in Circular RNA Levels in Myotonic Dystrophy

    Authors:
    Karol Czubak, Katarzyna Taylor, Agnieszka Piasecka, Krzysztof Sobczak, Katarzyna Kozlowska, Anna Philips, Saam Sedehizadeh, J. David Brook, Marzena Wojciechowska and Piotr Kozlowski
    Academic press:
    Frontiers in Genetics (year: 2019, volume: 10, pages: article 649), Publisher: Frontiers
    Status:
    Published
    DOI:
    10.3389/fgene.2019.00649 – link to the publication
  3. MBNL splicing activity depends on RNA binding site structural context

    Authors:
    Taylor K, Sznajder LJ, Cywoniuk P, Thomas JD, Swanson MS, Sobczak K.
    Academic press:
    Nucleic Acids Reseach (year: 2018, volume: 46, pages: 9119-9133), Publisher: Oxford University Press
    Status:
    Published
    DOI:
    10.1093/nar/gky565 – link to the publication
  4. Intrinsic regulatory role of RNA structural arrangement in alternative splicing control

    Authors:
    Taylor K., Sobczak K.
    Academic press:
    International Journal of Molecular Sciences (year: 2020, volume: 21, pages: 0), Publisher: Multidisciplinary Digital Publishing Institute
    Status:
    Published
    DOI:
    10.3390/ijms21145161 – link to the publication
  5. Loss of MBNL1 induces RNA mis-processing in the thymus and peripheral blood

    Authors:
    Sznajder J.L., Scotti M.M., Jihae Shin J., Taylor K., Ivankovic F., Nutter C.A., Aslam F.N., Subramony S.H., Ranum L.P., Swanson M.S.
    Academic press:
    Nature Communication (year: 2020, volume: 11, pages: 0), Publisher: Nature Research
    Status:
    Published
    DOI:
    10.1038/s41467-020-15962-x – link to the publication

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